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Protein Ontology report - animal opsin
PR:000001119 - http://purl.obolibrary.org/obo/PR_000001119
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001119   
  PRO nameanimal opsin 
  Synonyms
Other: EXACT:opsin receptor | type II opsin
  Definition"A rhodopsin-like G-protein coupled receptor that is a translation product of the human OPN1LW, OPN1MW, OPN1SW, RHO, OPN3, OPN4, or OPN5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof in Metazoa. The active form binds a vitamin A-based retinaldehyde chromophore through a Schiff base linkage to a Lys residue in the seventh transmembrane alpha helix." [PRO:WCB, PRO:XQ, Wikipedia:Opsin
  PRO Categoryfamily 
  ParentPR:000001094 rhodopsin-like G-protein coupled receptor
PR:000036194 eukaryotic protein
  TaxonNCBITaxon:33208 Metazoa
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 1                                        
         Gene8                                                  Organism-Gene 25                                        
         Sequence3                                                  Organism-Sequence 19                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF038544;IUPHARfam:975
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000001119

animal opsin

fam:AGTR


"A rhodopsin-like G-protein coupled receptor that is a translation product of the human OPN1LW, OPN1MW, OPN1SW, RHO, OPN3, OPN4, or OPN5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof in Metazoa. The active form binds a vitamin A-based retinaldehyde chromophore through a Schiff base linkage to a Lys residue in the seventh transmembrane alpha helix." [PRO:WCB, PRO:XQ, Wikipedia:Opsin]


gene



PR:000001180

opsin-5

OPN5


"An animal opsin that is a translation product of the human OPN5 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:Q6U736

opsin-5 (human)

hOPN5


"An opsin-5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q6U736]


organism-gene



PR:Q6VZZ7

opsin-5 (mouse)

mOPN5


"An opsin-5 that is encoded in the genome of mouse." [OMA:Q6VZZ7, PRO:DNx]


organism-sequence



PR:Q6VZZ7-1

opsin-5 isoform m1 (mouse)

mOPN5/iso:m1


"An opsin-5 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6VZZ7-1." [PRO:DNx, UniProtKB:Q6VZZ7]


organism-sequence



PR:Q6VZZ7-2

opsin-5 isoform m2 (mouse)

mOPN5/iso:m2


"An opsin-5 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6VZZ7-2." [PRO:DNx, UniProtKB:Q6VZZ7]


gene



PR:000001195

short-wave-sensitive opsin 1

OPN1SW


"An animal opsin that is a translation product of the human OPN1SW gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P03999

short-wave-sensitive opsin 1 (human)

hOPN1SW


"A short-wave-sensitive opsin 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P03999]


organism-sequence



PR:000061587

short-wave-sensitive opsin 1 sequence variant A264S (human)

hOPN1SW/var:A264S


"A short-wave-sensitive opsin 1 (human) that has a Ser residue at the position equivalent to Ala-264 of the amino acid sequence represented by UniProtKB:P03999. UniProtKB:P03999, Ala-264, CHEBI:29999." [PRO:DNx, Reactome:R-HSA-2470755]


organism-sequence



PR:000062331

short-wave-sensitive opsin 1 sequence variant C214P (human)

hOPN1SW/var:C214P


"A short-wave-sensitive opsin 1 (human) that has a Pro residue at the position equivalent to Cys-214 of the amino acid sequence represented by UniProtKB:P03999. UniProtKB:P03999, Cys-214, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-2470745]


organism-sequence



PR:000063234

short-wave-sensitive opsin 1 sequence variant L79R (human)

hOPN1SW/var:L79R


"A short-wave-sensitive opsin 1 (human) that has an Arg residue at the position equivalent to Leu-79 of the amino acid sequence represented by UniProtKB:P03999. UniProtKB:P03999, Leu-79, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-2470743]


organism-gene



PR:P28684

violet-sensitive opsin (chicken)

chick-OPN1SW


"A short-wave-sensitive opsin 1 that is encoded in the genome of chicken." [PANTHER:PTHR24240:SF25, PRO:DNx]


organism-gene



PR:P51491

short-wave-sensitive opsin 1 (mouse)

mOPN1SW


"A short-wave-sensitive opsin 1 that is encoded in the genome of mouse." [OMA:P51491, PRO:DNx]


organism-gene



PR:Q63652

short-wave-sensitive opsin 1 (rat)

rOPN1SW


"A short-wave-sensitive opsin 1 that is encoded in the genome of rat." [OMA:Q63652, PRO:DNx]


organism-gene



PR:Q9W6A9

opsin-1, short-wave-sensitive 1 (zebrafish)

z-OPN1SW


"A short-wave-sensitive opsin 1 that is encoded in the genome of zebrafish." [PRO:WCB]


gene



PR:000001220

encephalopsin

OPN3


"An animal opsin that is a translation product of the human OPN3 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:Q9H1Y3

opsin-3 (human)

hOPN3


"An encephalopsin that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q9H1Y3]


organism-sequence



PR:Q9H1Y3-1

opsin-3 isoform h1 (human)

hOPN3/iso:h1


"An opsin-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H1Y3-1." [PRO:DNx, UniProtKB:Q9H1Y3]


organism-sequence



PR:Q9H1Y3-2

opsin-3 isoform h2 (human)

hOPN3/iso:h2


"An opsin-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H1Y3-2." [PRO:DNx, UniProtKB:Q9H1Y3]


organism-modification



PR:000082857

opsin-3 deaminated 1 (human)

hOPN3/Deam:1


"An opsin-3 (human) that has been deaminated on the residue at the position equivalent to Gln-346 of the amino acid sequence represented by UniProtKB:Q9H1Y3-1. Example: UniProtKB:Q9H1Y3-1, Gln-346, MOD:00685." [IEDB_epitope:1580714, PRO:DNx]


organism-gene



PR:Q9WUK7

opsin-3 (mouse)

mOPN3


"An encephalopsin that is encoded in the genome of mouse." [OMA:Q9WUK7, PRO:DNx]


gene



PR:000001224

medium-wave-sensitive opsin

OPN1MW


"An animal opsin that is a translation product of the human OPN1MW, OPN1MW2, or OPN1MW3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DAN, PRO:WCB]


organism-family



PR:000050522

medium-wave-sensitive opsin (human)

hOPN1MW


"A medium-wave-sensitive opsin that is encoded in the genome of human." [PRO:DAN]






PR:P04001

medium-wave-sensitive opsin 1 (human)











PR:P0DN77

medium-wave-sensitive opsin 2 (human)











PR:P0DN78

medium-wave-sensitive opsin 3 (human)







gene



PR:000001243

melanopsin

OPN4


"An animal opsin that is a translation product of the human OPN4 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P08099

opsin Rh2 (fruit fly)

fly-OPN4


"A melanopsin that is encoded in the genome of fruit fly." [OMA:P08099, PRO:DNx]


organism-gene



PR:Q8R456

melanopsin (rat)

rOPN4


"A melanopsin that is encoded in the genome of rat." [OMA:Q8R456, PRO:DNx]


organism-gene



PR:Q9QXZ9

melanopsin (mouse)

mOPN4


"A melanopsin that is encoded in the genome of mouse." [OMA:Q9QXZ9, PRO:DNx]


organism-sequence



PR:Q9QXZ9-1

melanopsin isoform 1 (mouse)

mOPN4/iso:1


"A melanopsin isoform 1 that is encoded in the genome of mouse." [PMID:10632589, PMID:19793992, PRO:HJD]

Yes

organism-sequence



PR:Q9QXZ9-2

melanopsin isoform 2 (mouse)

mOPN4/iso:2


"A melanopsin isoform 2 that is encoded in the genome of mouse." [PMID:19793992, PRO:HJD]

Yes

organism-gene



PR:Q9UHM6

melanopsin (human)

hOPN4


"A melanopsin that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q9UHM6]


organism-sequence



PR:Q9UHM6-1

melanopsin isoform h1 (human)

hOPN4/iso:h1


"A melanopsin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UHM6-1." [PRO:DNx, UniProtKB:Q9UHM6]


organism-sequence



PR:Q9UHM6-2

melanopsin isoform h2 (human)

hOPN4/iso:h2


"A melanopsin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UHM6-2." [PRO:DNx, UniProtKB:Q9UHM6]


sequence



PR:000035677

melanopsin isoform 1

OPN4/iso:1


"A melanopsin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QXZ9-1 or a 1:1 ortholog thereof." [PMID:10632589, PMID:19793992, PRO:HJD]


organism-sequence



PR:Q9QXZ9-1

melanopsin isoform 1 (mouse)

mOPN4/iso:1


"A melanopsin isoform 1 that is encoded in the genome of mouse." [PMID:10632589, PMID:19793992, PRO:HJD]

Yes

sequence



PR:000035679

melanopsin isoform 2

OPN4/iso:2


"A melanopsin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QXZ9-2 or a 1:1 ortholog thereof." [PMID:19793992, PRO:HJD]


organism-sequence



PR:Q9QXZ9-2

melanopsin isoform 2 (mouse)

mOPN4/iso:2


"A melanopsin isoform 2 that is encoded in the genome of mouse." [PMID:19793992, PRO:HJD]

Yes

gene



PR:000001244

long-wave-sensitive opsin 1

OPN1LW


"An animal opsin that is a translation product of the human OPN1LW gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P04000

long-wave-sensitive opsin 1 (human)

hOPN1LW


"A long-wave-sensitive opsin 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P04000]


organism-sequence



PR:000060789

long-wave-sensitive opsin 1 sequence variant C203R (human)

hOPN1LW/var:C203R


"A long-wave-sensitive opsin 1 (human) that has an Arg residue at the position equivalent to Cys-203 of the amino acid sequence represented by UniProtKB:P04000. UniProtKB:P04000, Cys-203, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-2471708]


organism-sequence



PR:000062869

long-wave-sensitive opsin 1 sequence variant G338E (human)

hOPN1LW/var:G338E


"A long-wave-sensitive opsin 1 (human) that has a Glu residue at the position equivalent to Gly-338 of the amino acid sequence represented by UniProtKB:P04000. UniProtKB:P04000, Gly-338, CHEBI:29972." [PRO:DNx, Reactome:R-HSA-2471646]


organism-sequence



PR:000064505

long-wave-sensitive opsin 1 sequence variant P307L (human)

hOPN1LW/var:P307L


"A long-wave-sensitive opsin 1 (human) that has a Leu residue at the position equivalent to Pro-307 of the amino acid sequence represented by UniProtKB:P04000. UniProtKB:P04000, Pro-307, CHEBI:30006." [PRO:DNx, Reactome:R-HSA-2471740]


gene



PR:000001245

rhodopsin

RHO


"An animal opsin that is a translation product of the human RHO gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P02699

rhodopsin (cow)

cow-RHO


"A rhodopsin that is encoded in the genome of cow." [OMA:P02699, PRO:DNx]


organism-gene



PR:P08100

rhodopsin (human)

hRHO


"A rhodopsin that is encoded in the genome of human." [PRO:WCB, UniProtKB:P08100]


organism-sequence



PR:P08100-1

rhodopsin isoform 1 (human)

hRHO/iso:1


"A rhodopsin isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000049043

rhodopsin phosphorylated 1 (human)

hRHO/Phos:1


"A rhodopsin (human) that has been post-translationally modified to include phosphoserine at positions 334, 338 and 343 of the amino acid sequence represented by UniProtKB:P08100. UniProtKB:P08100, Ser-334/Ser-338/Ser-343, MOD:00046." [PRO:DNx, Reactome:R-HSA-2581504]


organism-gene



PR:P15409

rhodopsin (mouse)

mRHO


"A rhodopsin that is encoded in the genome of mouse." [OMA:P15409, PRO:DNx]


organism-sequence



PR:P15409-1

rhodopsin isoform 1 (mouse)

mRHO/iso:1


"A rhodopsin isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:P22328

rhodopsin (chicken)

chick-RHO


"A rhodopsin that is encoded in the genome of chicken." [OMA:P22328, PRO:DNx]


organism-gene



PR:P35359

rhodopsin (zebrafish)

z-RHO


"A rhodopsin that is encoded in the genome of zebrafish." [PANTHER:PTHR24240:SF291, PRO:DNx]


organism-gene



PR:P51489

rhodopsin (rat)

rRHO


"A rhodopsin that is encoded in the genome of rat." [OMA:P51489, PRO:DNx]


organism-sequence



PR:P51489-1

rhodopsin isoform 1 (rat)

rRHO/iso:1


"A rhodopsin isoform 1 that is encoded in the genome of rat." [PRO:DNx]


sequence



PR:000038729

rhodopsin isoform 1

RHO/iso:1


"A rhodopsin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08100-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P08100-1

rhodopsin isoform 1 (human)

hRHO/iso:1


"A rhodopsin isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P15409-1

rhodopsin isoform 1 (mouse)

mRHO/iso:1


"A rhodopsin isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P51489-1

rhodopsin isoform 1 (rat)

rRHO/iso:1


"A rhodopsin isoform 1 that is encoded in the genome of rat." [PRO:DNx]


gene



PR:000001248

visual pigment-like receptor peropsin

RRH


"An animal opsin that is a translation product of the human RRH gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:O14718

visual pigment-like receptor peropsin (human)

hRRH


"A visual pigment-like receptor peropsin that is encoded in the genome of human." [PRO:WCB, UniProtKB:O14718]


organism-gene



PR:O35214

visual pigment-like receptor peropsin (mouse)

mRRH


"A visual pigment-like receptor peropsin that is encoded in the genome of mouse." [OMA:O35214, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9QXZ9-1 mOPN4/iso:1 acts_upstream_of_or_withinGO:0016056 G protein-coupled opsin signaling pathway MGI_ref:4438311; PMID:19793992
enablesGO:0008020 G protein-coupled photoreceptor activity MGI_ref:4438311; PMID:19793992
located_inGO:0005886 plasma membrane MGI_ref:4438311; PMID:19793992
PR:Q9QXZ9-2 mOPN4/iso:2 acts_upstream_of_or_withinGO:0016056 G protein-coupled opsin signaling pathway MGI_ref:4438311; PMID:19793992
enablesGO:0008020 G protein-coupled photoreceptor activity MGI_ref:4438311; PMID:19793992
located_inGO:0005886 plasma membrane MGI_ref:4438311; PMID:19793992