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Protein Ontology report - T-cell surface glycoprotein CD8 beta chain
PR:000001085 - http://purl.obolibrary.org/obo/PR_000001085
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000001085   
  PRO nameT-cell surface glycoprotein CD8 beta chain 
  Synonyms
PRO-Short-label: EXACT:CD8B
Gene-based: RELATED:CD8B1 | Ly-3 | Lyt-3 | Lyt3
Other: EXACT:lymphocyte antigen 3 | T-cell membrane glycoprotein Ly-3 | T-cell surface glycoprotein Lyt-3
  Definition"A protein that is a translation product of the human CD8B gene or a 1:1 ortholog thereof. CD8 is a transmembrane receptor that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain." [PRO:CNA, Wikipedia:CD8] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 8                                        
         Modification3                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF002020
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001085
T-cell surface glycoprotein CD8 beta chain
CD8B
"A protein that is a translation product of the human CD8B gene or a 1:1 ortholog thereof. CD8 is a transmembrane receptor that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain." [PRO:CNA, Wikipedia:CD8]

organism-gene


PR:P05541
T-cell surface glycoprotein CD8 beta chain (rat)
rCD8B
"A T-cell surface glycoprotein CD8 beta chain that is encoded in the genome of rat." [PRO:CNA]

organism-gene


PR:P10300
T-cell surface glycoprotein CD8 beta chain (mouse)
mCD8B
"A T-cell surface glycoprotein CD8 beta chain that is encoded in the genome of mouse." [PRO:CNA]

organism-gene


PR:P10966
T-cell surface glycoprotein CD8 beta chain (human)
hCD8B
"A T-cell surface glycoprotein CD8 beta chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P10966]

organism-sequence


PR:P10966-1
T-cell surface glycoprotein CD8 beta chain isoform 1 (human)
hCD8B/iso:1
"A T-cell surface glycoprotein CD8 beta chain isoform 1 that is encoded in the genome of human." [PRO:DAN]

organism-sequence


PR:P10966-2
T-cell surface glycoprotein CD8 beta chain isoform h2 (human)
hCD8B/iso:h2
"A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-2." [PRO:DNx, UniProtKB:P10966]

organism-sequence


PR:P10966-3
T-cell surface glycoprotein CD8 beta chain isoform h3 (human)
hCD8B/iso:h3
"A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-3." [PRO:DNx, UniProtKB:P10966]

organism-sequence


PR:P10966-4
T-cell surface glycoprotein CD8 beta chain isoform h4 (human)
hCD8B/iso:h4
"A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-4." [PRO:DNx, UniProtKB:P10966]

organism-sequence


PR:P10966-6
T-cell surface glycoprotein CD8 beta chain isoform h5 (human)
hCD8B/iso:h5
"A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-6." [PRO:DNx, UniProtKB:P10966]

organism-sequence


PR:P10966-7
T-cell surface glycoprotein CD8 beta chain isoform h6 (human)
hCD8B/iso:h6
"A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-7." [PRO:DNx, UniProtKB:P10966]

organism-sequence


PR:P10966-8
T-cell surface glycoprotein CD8 beta chain isoform h7 (human)
hCD8B/iso:h7
"A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-8." [PRO:DNx, UniProtKB:P10966]

organism-sequence


PR:P10966-9
T-cell surface glycoprotein CD8 beta chain isoform h8 (human)
hCD8B/iso:h8
"A T-cell surface glycoprotein CD8 beta chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-9." [PRO:DNx, UniProtKB:P10966]

organism-modification


PR:000046654
T-cell surface glycoprotein CD8 beta chain, signal peptide removed form (human)
hCD8B/SigPep-
"A T-cell surface glycoprotein CD8 beta chain (human) that has had the signal peptide removed. UniProtKB:P10966, 22-210." [PRO:DNx, Reactome:R-HSA-2980537, Reactome:R-HSA-3149571]

sequence


PR:000025405
T-cell surface glycoprotein CD8 beta chain isoform 1
CD8B/iso:1
"A T-cell surface glycoprotein CD8 beta chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-1 or a 1:1 ortholog thereof." [PRO:DAN]

organism-sequence


PR:P10966-1
T-cell surface glycoprotein CD8 beta chain isoform 1 (human)
hCD8B/iso:1
"A T-cell surface glycoprotein CD8 beta chain isoform 1 that is encoded in the genome of human." [PRO:DAN]

modification


PR:000025407
T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed form
CD8B/iso:1/SigPep-
"A T-cell surface glycoprotein CD8 beta chain isoform 1 that has had the signal peptide removed to yield the mature form." [PRO:DAN]

modification


PR:000025409
T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed glycosylated form
CD8B/iso:1/SigPep-/GlycoRes+
"A T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed form that includes at least one glycosylated residue." [PRO:DAN]

Yes
modification


PR:000018337
T-cell surface glycoprotein CD8 beta chain, signal peptide removed form
CD8B/SigPep-
"A T-cell surface glycoprotein CD8 beta chain that has had the signal peptide removed." [PRO:DNx]

modification


PR:000025407
T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed form
CD8B/iso:1/SigPep-
"A T-cell surface glycoprotein CD8 beta chain isoform 1 that has had the signal peptide removed to yield the mature form." [PRO:DAN]

modification


PR:000025409
T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed glycosylated form
CD8B/iso:1/SigPep-/GlycoRes+
"A T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed form that includes at least one glycosylated residue." [PRO:DAN]

Yes
organism-modification


PR:000046654
T-cell surface glycoprotein CD8 beta chain, signal peptide removed form (human)
hCD8B/SigPep-
"A T-cell surface glycoprotein CD8 beta chain (human) that has had the signal peptide removed. UniProtKB:P10966, 22-210." [PRO:DNx, Reactome:R-HSA-2980537, Reactome:R-HSA-3149571]

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CD8B forms found in complexes   

CD8B Component
 Complexes
PR:000025409 CD8B/iso:1/SigPep-/GlycoRes+ PR:000025402 T cell receptor co-receptor CD8