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Protein Ontology report - CD2 molecule
PR:000001083 - http://purl.obolibrary.org/obo/PR_000001083
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001083   
  PRO nameCD2 molecule 
  Synonyms
PRO-Short-label: EXACT:CD2
Gene-based: RELATED:SRBC
Other: EXACT:erythrocyte receptor | LFA-2 | LFA-3 receptor | ly-37 | lymphocyte antigen 37 | rosette receptor | T-cell surface antigen CD2 | T-cell surface antigen T11/Leu-5 | T-cell surface glycoprotein CD2
  Definition"A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  CommentRequested by=CL. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification4                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF001984;IUPHARobj:2600
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000001083

CD2 molecule

CD2


"A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P06729

T-cell surface antigen CD2 (human)

hCD2


"A CD2 molecule that is encoded in the genome of human." [PRO:CNA, UniProtKB:P06729]


organism-sequence



PR:P06729-1

T-cell surface antigen CD2 isoform 1 (human)

hCD2/iso:1


"A CD2 molecule isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036596

CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 (human)

hCD2/iso:1/SigPep-/NGlyco:1


"A CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:P06729-1, 25-351, Asn-89, MOD:00160." [PMID:1385399, PMID:7544493, PMID:7688025, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000046618

T-cell surface antigen CD2, signal peptide removed form (human)

hCD2/SigPep-


"A T-cell surface antigen CD2 (human) that has had the signal peptide removed. UniProtKB:P06729, 25-351." [PRO:DNx, Reactome:R-HSA-197795]


organism-modification



PR:000036596

CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 (human)

hCD2/iso:1/SigPep-/NGlyco:1


"A CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:P06729-1, 25-351, Asn-89, MOD:00160." [PMID:1385399, PMID:7544493, PMID:7688025, PRO:CNA, PRO:DAN]

Yes

organism-gene



PR:P08920

T-cell surface antigen CD2 (mouse)

mCD2


"A CD2 molecule that is encoded in the genome of mouse." [OMA:P08920, PRO:DNx]


organism-sequence



PR:P08920-1

T-cell surface antigen CD2 isoform 1 (mouse)

mCD2/iso:1


"A CD2 molecule isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-gene



PR:P08921

T-cell surface antigen CD2 (rat)

rCD2


"A CD2 molecule that is encoded in the genome of rat." [OMA:P08921, PRO:DNx]


sequence



PR:000001114

CD2 molecule isoform 1

CD2/iso:1


"A CD2 molecule that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06729-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P06729-1

T-cell surface antigen CD2 isoform 1 (human)

hCD2/iso:1


"A CD2 molecule isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036596

CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 (human)

hCD2/iso:1/SigPep-/NGlyco:1


"A CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:P06729-1, 25-351, Asn-89, MOD:00160." [PMID:1385399, PMID:7544493, PMID:7688025, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:P08920-1

T-cell surface antigen CD2 isoform 1 (mouse)

mCD2/iso:1


"A CD2 molecule isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


modification



PR:000025464

CD2 molecule isoform 1, signal peptide removed form

CD2/iso:1/SigPep-


"A CD2 molecule isoform 1 that has had the signal peptide removed." [PRO:DAN]


modification



PR:000001249

CD2 molecule isoform 1, signal peptide removed N-glycosylated 1

CD2/iso:1/SigPep-/NGlyco:1


"A CD2 molecule isoform 1, signal peptide removed form that has been N-glycosylated. The N-glycosylation seems to be essential for adhesion functions. Example: UniProtKB:P06729-1, 25-351, Asn-89, MOD:00160." [PMID:1385399]


organism-modification



PR:000036596

CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 (human)

hCD2/iso:1/SigPep-/NGlyco:1


"A CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:P06729-1, 25-351, Asn-89, MOD:00160." [PMID:1385399, PMID:7544493, PMID:7688025, PRO:CNA, PRO:DAN]

Yes

modification



PR:000018333

CD2 molecule, signal peptide removed form

CD2/SigPep-


"A CD2 molecule that has had the signal peptide removed." [PRO:DNx]


modification



PR:000025464

CD2 molecule isoform 1, signal peptide removed form

CD2/iso:1/SigPep-


"A CD2 molecule isoform 1 that has had the signal peptide removed." [PRO:DAN]


modification



PR:000001249

CD2 molecule isoform 1, signal peptide removed N-glycosylated 1

CD2/iso:1/SigPep-/NGlyco:1


"A CD2 molecule isoform 1, signal peptide removed form that has been N-glycosylated. The N-glycosylation seems to be essential for adhesion functions. Example: UniProtKB:P06729-1, 25-351, Asn-89, MOD:00160." [PMID:1385399]


organism-modification



PR:000036596

CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 (human)

hCD2/iso:1/SigPep-/NGlyco:1


"A CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:P06729-1, 25-351, Asn-89, MOD:00160." [PMID:1385399, PMID:7544493, PMID:7688025, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000046618

T-cell surface antigen CD2, signal peptide removed form (human)

hCD2/SigPep-


"A T-cell surface antigen CD2 (human) that has had the signal peptide removed. UniProtKB:P06729, 25-351." [PRO:DNx, Reactome:R-HSA-197795]


organism-modification



PR:000036596

CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 (human)

hCD2/iso:1/SigPep-/NGlyco:1


"A CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:P06729-1, 25-351, Asn-89, MOD:00160." [PMID:1385399, PMID:7544493, PMID:7688025, PRO:CNA, PRO:DAN]

Yes

modification



PR:000025455

CD2 molecule proteolytic cleavage product

CD2/ClvPrd


"A CD2 molecule that has been processed by proteolytic cleavage." [PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036596 hCD2/iso:1/SigPep-/NGlyco:1
UniProtKB:P06729-1, 25-351, Asn-89, MOD:00160
acts_upstream_of_or_withinGO:0007155 cell adhesion PMID:1385399
enablesGO:0005515 protein binding with PR:P19256 Ag3 (human) PMID:7544493; PMID:7688025