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family
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PR:000001043 |
Na(+)/H(+) exchange regulatory cofactor with ERM-binding domain
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NHERF1/iso:1
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"A protein that consists of two copies of the PDZ domain (Pfam:PF00595) and a copy of the EBP50, C-terminal (Pfam:PF09007) domain." [PMID:15905209]
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gene
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PR:000001041 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1
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NHERF1
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"A Na(+)/H(+) exchange regulatory cofactor with ERM-binding domain that is a translation product of the human NHERF1 gene or a 1:1 ortholog thereof. It contains two copies of the PDZ domain at the N terminus and an EBP50 domain at the C-terminus. The latter allows interaction with FERM domains, resulting in the activation of ERM proteins (PR:000001030), with subsequent cytoskeletal modulation and cellular growth control." [PRO:CNA]
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organism-gene
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PR:O14745 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (human)
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hNHERF1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O14745]
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organism-sequence
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PR:O14745-1 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (human)
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hNHERF1/iso:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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organism-sequence
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PR:O14745-2 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform h2 (human)
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hNHERF1/iso:h2
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14745-2." [PRO:DNx, UniProtKB:O14745]
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organism-modification
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PR:000084870 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 methylated 1 (human)
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hNHERF1/Me:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (human) that has been methylated on the residue at the position equivalent to Cys-206 of the amino acid sequence represented by UniProtKB:O14745-1. Example: UniProtKB:O14745-1, Cys-206, MOD:00660." [IEDB_epitope:1010282, PRO:DNx]
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organism-gene
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PR:P70441 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (mouse)
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mNHERF1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 that is encoded in the genome of mouse." [OMA:P70441, PRO:DNx]
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organism-sequence
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PR:P70441-1 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (mouse)
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mNHERF1/iso:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-sequence
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PR:P70441-2 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 2 (mouse)
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mNHERF1/iso:2
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
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organism-modification
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PR:000046189 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 phosphorylated 1 (mouse)
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mNHERF1/Phos:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (mouse) that has been phosphorylated on the residue at the position equivalent to Ser-77 of the amino acid sequence represented by UniProtKB:P70441-1. Example: UniProtKB:P70441-1, Ser-77, MOD:00046." [iPTMnet:P70441, PMID:17975671]
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organism-gene
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PR:Q5ZM14 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (chicken)
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chick-NHERF1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 that is encoded in the genome of chicken." [PRO:CNA]
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organism-gene
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PR:Q9JJ19 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (rat)
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rNHERF1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 that is encoded in the genome of rat." [OMA:Q9JJ19, PRO:DNx]
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organism-sequence
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PR:Q9JJ19-1 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (rat)
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rNHERF1/iso:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 that is encoded in the genome of rat." [PRO:CNA]
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sequence
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PR:000001042 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1
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NHERF1/iso:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14745-1 or a 1:1 ortholog thereof." [PRO:CNA]
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organism-sequence
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PR:O14745-1 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (human)
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hNHERF1/iso:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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organism-sequence
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PR:P70441-1 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (mouse)
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mNHERF1/iso:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-sequence
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PR:Q9JJ19-1 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (rat)
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rNHERF1/iso:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 that is encoded in the genome of rat." [PRO:CNA]
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modification
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PR:000026596 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1, initiator methionine removed form
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NHERF1/iso:1/InitMet-
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]
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sequence
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PR:000001058 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 2
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NHERF1/iso:2
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70441-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:P70441-2 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 2 (mouse)
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mNHERF1/iso:2
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
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modification
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PR:000018331 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1, initiator methionine removed form
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NHERF1/InitMet-
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 that has had the initiator methionine removed." [PRO:DNx]
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modification
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PR:000026596 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1, initiator methionine removed form
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NHERF1/iso:1/InitMet-
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]
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gene
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PR:000015215 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2
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NHERF2
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"A Na(+)/H(+) exchange regulatory cofactor with ERM-binding domain that is a translation product of the human NHERF2 gene or a 1:1 ortholog thereof." [PRO:DNx]
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organism-gene
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PR:Q15599 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (human)
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hNHERF2
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15599]
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organism-sequence
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PR:Q15599-1 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1 (human)
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hNHERF2/iso:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
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organism-sequence
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PR:Q15599-2 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform h2 (human)
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hNHERF2/iso:h2
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15599-2." [PRO:DNx, UniProtKB:Q15599]
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organism-sequence
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PR:Q15599-3 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform h3 (human)
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hNHERF2/iso:h3
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15599-3." [PRO:DNx, UniProtKB:Q15599]
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organism-modification
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PR:000071702 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 deaminated 1 (human)
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hNHERF2/Deam:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (human) that has been deaminated on the residue at the position equivalent to Gln-202 of the amino acid sequence represented by UniProtKB:Q15599-1. Example: UniProtKB:Q15599-1, Gln-202, MOD:00685." [IEDB_epitope:2142616, PRO:DNx]
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organism-modification
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PR:000082185 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 deaminated 2 (human)
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hNHERF2/Deam:2
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (human) that has been deaminated on the residue at the position equivalent to Asn-200 of the amino acid sequence represented by UniProtKB:Q15599-1. Example: UniProtKB:Q15599-1, Asn-200, MOD:00684." [IEDB_epitope:2142615, PRO:DNx]
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organism-gene
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PR:Q920G2 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (rat)
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rNHERF2
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 that is encoded in the genome of rat." [OMA:Q920G2, PRO:DNx]
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organism-gene
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PR:Q9JHL1 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (mouse)
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mNHERF2
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 that is encoded in the genome of mouse." [OMA:Q9JHL1, PRO:DNx]
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organism-sequence
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PR:Q9JHL1-1 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1 (mouse)
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mNHERF2/iso:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
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organism-sequence
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PR:Q9JHL1-2 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform m2 (mouse)
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mNHERF2/iso:m2
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JHL1-2." [PRO:DNx, UniProtKB:Q9JHL1]
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sequence
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PR:000040655 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1
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NHERF2/iso:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15599-1 or a 1:1 ortholog thereof." [PRO:DNx]
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organism-sequence
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PR:Q15599-1 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1 (human)
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hNHERF2/iso:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
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organism-sequence
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PR:Q9JHL1-1 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1 (mouse)
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mNHERF2/iso:1
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"A Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
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