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Protein Ontology report - WW domain-containing oxidoreductase
PR:000001036 - http://purl.obolibrary.org/obo/PR_000001036
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001036   
  PRO nameWW domain-containing oxidoreductase 
  Synonyms
PRO-Short-label: EXACT:WWOX
Gene-based: RELATED:FOR | SDR41C1 | WOX1
Other: EXACT:fragile site FRA16D oxidoreductase
  Definition"A protein that is a translation product of the human WWOX gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence6                                                  Organism-Sequence 11                                        
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF038706
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000001036

WW domain-containing oxidoreductase

WWOX


"A protein that is a translation product of the human WWOX gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:Q5F389

WW domain-containing oxidoreductase (chicken)

chick-WWOX


"A WW domain-containing oxidoreductase that is encoded in the genome of chicken." [OMA:Q5F389, PRO:DNx]


organism-gene



PR:Q803A8

WW domain-containing oxidoreductase (zebrafish)

z-WWOX


"A WW domain-containing oxidoreductase that is encoded in the genome of zebrafish." [PRO:CNA]


organism-gene



PR:Q91WL8

WW domain-containing oxidoreductase (mouse)

mWWOX


"A WW domain-containing oxidoreductase that is encoded in the genome of mouse." [OMA:Q91WL8, PRO:DNx]


organism-sequence



PR:Q91WL8-1

WW domain-containing oxidoreductase isoform 1 (mouse)

mWWOX/iso:1


"A WW domain-containing oxidoreductase isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:Q91WL8-2

WW domain-containing oxidoreductase isoform m2 (mouse)

mWWOX/iso:m2


"A WW domain-containing oxidoreductase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q91WL8-2." [PRO:DNx, UniProtKB:Q91WL8]


organism-sequence



PR:Q91WL8-3

WW domain-containing oxidoreductase isoform m3 (mouse)

mWWOX/iso:m3


"A WW domain-containing oxidoreductase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q91WL8-3." [PRO:DNx, UniProtKB:Q91WL8]


organism-sequence



PR:Q91WL8-4

WW domain-containing oxidoreductase isoform m4 (mouse)

mWWOX/iso:m4


"A WW domain-containing oxidoreductase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q91WL8-4." [PRO:DNx, UniProtKB:Q91WL8]


organism-gene



PR:Q9NZC7

WW domain-containing oxidoreductase (human)

hWWOX


"A WW domain-containing oxidoreductase that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9NZC7]


organism-sequence



PR:Q9NZC7-1

WW domain-containing oxidoreductase isoform 1 (human)

hWWOX/iso:1


"A WW domain-containing oxidoreductase isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-sequence



PR:Q9NZC7-2

WW domain-containing oxidoreductase isoform 2 (human)

hWWOX/iso:2


"A WW domain-containing oxidoreductase isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q9NZC7-3

WW domain-containing oxidoreductase isoform 3 (human)

hWWOX/iso:3


"A WW domain-containing oxidoreductase isoform 3 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q9NZC7-4

WW domain-containing oxidoreductase isoform 4 (human)

hWWOX/iso:4


"A WW domain-containing oxidoreductase isoform 4 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q9NZC7-5

WW domain-containing oxidoreductase isoform 5 (human)

hWWOX/iso:5


"A WW domain-containing oxidoreductase isoform 5 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NZC7]


organism-sequence



PR:Q9NZC7-6

WW domain-containing oxidoreductase isoform 6 (human)

hWWOX/iso:6


"A WW domain-containing oxidoreductase isoform 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NZC7]


organism-sequence



PR:Q9NZC7-7

WW domain-containing oxidoreductase isoform h7 (human)

hWWOX/iso:h7


"A WW domain-containing oxidoreductase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZC7-7." [PRO:DNx, UniProtKB:Q9NZC7]


organism-modification



PR:000046076

WW domain-containing oxidoreductase phosphorylated 1 (human)

hWWOX/Phos:1


"A WW domain-containing oxidoreductase (human) that has been phosphorylated on the residue at the position equivalent to Tyr-33 of the amino acid sequence represented by UniProtKB:Q9NZC7-1. Example: UniProtKB:Q9NZC7-1, Tyr-33, MOD:00048." [iPTMnet:Q9NZC7, PMID:15070730]


organism-gene



PR:Q9VLU5

WW domain-containing oxidoreductase (fruit fly)

fly-WWOX


"A WW domain-containing oxidoreductase that is encoded in the genome of fruit fly." [OMA:Q9VLU5, PRO:DNx]


sequence



PR:000001037

WW domain-containing oxidoreductase isoform 1

WWOX/iso:1


"A WW domain-containing oxidoreductase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZC7-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q91WL8-1

WW domain-containing oxidoreductase isoform 1 (mouse)

mWWOX/iso:1


"A WW domain-containing oxidoreductase isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:Q9NZC7-1

WW domain-containing oxidoreductase isoform 1 (human)

hWWOX/iso:1


"A WW domain-containing oxidoreductase isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

modification



PR:000002696

WW domain-containing oxidoreductase isoform 1 unmodified form

WWOX/iso:1/UnMod


"A WW domain-containing oxidoreductase isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]


sequence



PR:000001053

WW domain-containing oxidoreductase isoform 2

WWOX/iso:2


"A WW domain-containing oxidoreductase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZC7-2 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q9NZC7-2

WW domain-containing oxidoreductase isoform 2 (human)

hWWOX/iso:2


"A WW domain-containing oxidoreductase isoform 2 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000001054

WW domain-containing oxidoreductase isoform 3

WWOX/iso:3


"A WW domain-containing oxidoreductase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZC7-3 or a 1:1 ortholog thereof. This form lacks the C-terminal short chain dehydrogenase domain." [PRO:CNA]


organism-sequence



PR:Q9NZC7-3

WW domain-containing oxidoreductase isoform 3 (human)

hWWOX/iso:3


"A WW domain-containing oxidoreductase isoform 3 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000001055

WW domain-containing oxidoreductase isoform 4

WWOX/iso:4


"A WW domain-containing oxidoreductase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZC7-4 or a 1:1 ortholog thereof. This is form is truncated within the first WW domain, and is about 37 residues long." [PRO:CNA]


organism-sequence



PR:Q9NZC7-4

WW domain-containing oxidoreductase isoform 4 (human)

hWWOX/iso:4


"A WW domain-containing oxidoreductase isoform 4 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000001056

WW domain-containing oxidoreductase isoform 5

WWOX/iso:5


"A WW domain-containing oxidoreductase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZC7-5 or a 1:1 ortholog thereof. This form lacks the short chain dehydrogenase domain but includes the rest of the C-terminal sequence." [PMID:11719429]


organism-sequence



PR:Q9NZC7-5

WW domain-containing oxidoreductase isoform 5 (human)

hWWOX/iso:5


"A WW domain-containing oxidoreductase isoform 5 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NZC7]


sequence



PR:000001057

WW domain-containing oxidoreductase isoform 6

WWOX/iso:6


"A WW domain-containing oxidoreductase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZC7-6 or a 1:1 ortholog thereof. This form contains an alternative sequence after the two WW domains and the predicted nucleotide binding site, as compared to isoform 1. Originated by exons deletions and frameshift." [PMID:11719429]


organism-sequence



PR:Q9NZC7-6

WW domain-containing oxidoreductase isoform 6 (human)

hWWOX/iso:6


"A WW domain-containing oxidoreductase isoform 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NZC7]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9NZC7-1 hWWOX/iso:1 enablesGO:0005515 protein binding with PR:000036589 hEZR/iso:1/Phos:2 PMID:16438931