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Protein Ontology report - CD3 gamma
PR:000001021 - http://purl.obolibrary.org/obo/PR_000001021
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001021   
  PRO nameCD3 gamma 
  Synonyms
PRO-Short-label: EXACT:CD3G
Gene-based: RELATED:T3G
Other: EXACT:CD3g | T-cell receptor T3 gamma chain
  Definition"A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3G gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000001018 CD3 subunit with immunoglobulin domain
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001021
CD3 gamma
CD3G
"A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3G gene or a 1:1 ortholog thereof." [PRO:CNA]

organism-gene


PR:P09693
T-cell surface glycoprotein CD3 gamma chain (human)
hCD3G
"A CD3 gamma that is encoded in the genome of human." [PRO:CNA, UniProtKB:P09693]

organism-sequence


PR:P09693-1
T-cell surface glycoprotein CD3 gamma chain isoform 1 (human)
hCD3G/iso:1
"A CD3 gamma isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000025780
CD3 gamma isoform 1, signal peptide removed phosphorylated 1 (human)
hCD3G/iso:1/SigPep-/Phos:1
"A CD3 gamma isoform 1, signal peptide removed phosphorylated 1 in human. UniProtKB:P09693-1, 23-182, Tyr-160/Tyr-171, MOD:00048." [PRO:CNA]
Yes
Yes
organism-modification


PR:000046640
T-cell surface glycoprotein CD3 gamma chain, signal peptide removed form (human)
hCD3G/SigPep-
"A T-cell surface glycoprotein CD3 gamma chain (human) that has had the signal peptide removed. UniProtKB:P09693, 23-182." [PRO:DNx, Reactome:R-HSA-197917, Reactome:R-HSA-8869080]

organism-modification


PR:000025780
CD3 gamma isoform 1, signal peptide removed phosphorylated 1 (human)
hCD3G/iso:1/SigPep-/Phos:1
"A CD3 gamma isoform 1, signal peptide removed phosphorylated 1 in human. UniProtKB:P09693-1, 23-182, Tyr-160/Tyr-171, MOD:00048." [PRO:CNA]
Yes
Yes
organism-modification


PR:000070129
T-cell surface glycoprotein CD3 gamma chain phosphorylated 1 (human)
hCD3G/Phos:1
"A T-cell surface glycoprotein CD3 gamma chain (human) that has been phosphorylated on the residue at the position equivalent to Tyr-171 of the amino acid sequence represented by UniProtKB:P09693. UniProtKB:P09693, Tyr-171, MOD:00048." [IEDB_epitope:2146099, PRO:DNx]

organism-modification


PR:000074695
T-cell surface glycoprotein CD3 gamma chain phosphorylated 2 (human)
hCD3G/Phos:2
"A T-cell surface glycoprotein CD3 gamma chain (human) that has been phosphorylated on the residue at the position equivalent to Ser-172 of the amino acid sequence represented by UniProtKB:P09693. UniProtKB:P09693, Ser-172, MOD:00046." [IEDB_epitope:2146098, IEDB_epitope:2146100, IEDB_epitope:2146172, PRO:DNx]

organism-gene


PR:P11942
T-cell surface glycoprotein CD3 gamma chain (mouse)
mCD3G
"A CD3 gamma that is encoded in the genome of mouse." [OMA:P11942, PRO:DNx]

organism-sequence


PR:P11942-1
T-cell surface glycoprotein CD3 gamma chain isoform 1 (mouse)
mCD3G/iso:1
"A CD3 gamma isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

organism-gene


PR:Q64159
T-cell surface glycoprotein CD3 gamma chain (rat)
rCD3G
"A CD3 gamma that is encoded in the genome of rat." [OMA:Q64159, PRO:DNx]

sequence


PR:000025778
CD3 gamma isoform 1
CD3G/iso:1
"A CD3 gamma that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09693-1 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:P09693-1
T-cell surface glycoprotein CD3 gamma chain isoform 1 (human)
hCD3G/iso:1
"A CD3 gamma isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000025780
CD3 gamma isoform 1, signal peptide removed phosphorylated 1 (human)
hCD3G/iso:1/SigPep-/Phos:1
"A CD3 gamma isoform 1, signal peptide removed phosphorylated 1 in human. UniProtKB:P09693-1, 23-182, Tyr-160/Tyr-171, MOD:00048." [PRO:CNA]
Yes
Yes
organism-sequence


PR:P11942-1
T-cell surface glycoprotein CD3 gamma chain isoform 1 (mouse)
mCD3G/iso:1
"A CD3 gamma isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

modification


PR:000025779
CD3 gamma isoform 1, signal peptide removed phosphorylated 1
CD3G/iso:1/SigPep-/Phos:1
"A CD3 gamma isoform 1 that has had the signal peptide removed and has been phosphorylated on two Tyr residues within the ITAM domain. Example: UniProtKB:P09693-1, 23-182, Tyr-160/Tyr-171, MOD:00048." [PMID:20516133, PRO:CNA, PRO:DAN]

Yes
organism-modification


PR:000025780
CD3 gamma isoform 1, signal peptide removed phosphorylated 1 (human)
hCD3G/iso:1/SigPep-/Phos:1
"A CD3 gamma isoform 1, signal peptide removed phosphorylated 1 in human. UniProtKB:P09693-1, 23-182, Tyr-160/Tyr-171, MOD:00048." [PRO:CNA]
Yes
Yes
modification


PR:000026575
CD3 gamma isoform 1, signal peptide removed form
CD3G/iso:1/SigPep-
"A CD3 gamma isoform 1 that has had the signal peptide removed." [PRO:DNx]

modification


PR:000025779
CD3 gamma isoform 1, signal peptide removed phosphorylated 1
CD3G/iso:1/SigPep-/Phos:1
"A CD3 gamma isoform 1 that has had the signal peptide removed and has been phosphorylated on two Tyr residues within the ITAM domain. Example: UniProtKB:P09693-1, 23-182, Tyr-160/Tyr-171, MOD:00048." [PMID:20516133, PRO:CNA, PRO:DAN]

Yes
organism-modification


PR:000025780
CD3 gamma isoform 1, signal peptide removed phosphorylated 1 (human)
hCD3G/iso:1/SigPep-/Phos:1
"A CD3 gamma isoform 1, signal peptide removed phosphorylated 1 in human. UniProtKB:P09693-1, 23-182, Tyr-160/Tyr-171, MOD:00048." [PRO:CNA]
Yes
Yes
modification


PR:000018323
CD3 gamma, signal peptide removed form
CD3G/SigPep-
"A CD3 gamma that has had the signal peptide removed." [PRO:DNx]

modification


PR:000026575
CD3 gamma isoform 1, signal peptide removed form
CD3G/iso:1/SigPep-
"A CD3 gamma isoform 1 that has had the signal peptide removed." [PRO:DNx]

modification


PR:000025779
CD3 gamma isoform 1, signal peptide removed phosphorylated 1
CD3G/iso:1/SigPep-/Phos:1
"A CD3 gamma isoform 1 that has had the signal peptide removed and has been phosphorylated on two Tyr residues within the ITAM domain. Example: UniProtKB:P09693-1, 23-182, Tyr-160/Tyr-171, MOD:00048." [PMID:20516133, PRO:CNA, PRO:DAN]

Yes
organism-modification


PR:000025780
CD3 gamma isoform 1, signal peptide removed phosphorylated 1 (human)
hCD3G/iso:1/SigPep-/Phos:1
"A CD3 gamma isoform 1, signal peptide removed phosphorylated 1 in human. UniProtKB:P09693-1, 23-182, Tyr-160/Tyr-171, MOD:00048." [PRO:CNA]
Yes
Yes
organism-modification


PR:000046640
T-cell surface glycoprotein CD3 gamma chain, signal peptide removed form (human)
hCD3G/SigPep-
"A T-cell surface glycoprotein CD3 gamma chain (human) that has had the signal peptide removed. UniProtKB:P09693, 23-182." [PRO:DNx, Reactome:R-HSA-197917, Reactome:R-HSA-8869080]

organism-modification


PR:000025780
CD3 gamma isoform 1, signal peptide removed phosphorylated 1 (human)
hCD3G/iso:1/SigPep-/Phos:1
"A CD3 gamma isoform 1, signal peptide removed phosphorylated 1 in human. UniProtKB:P09693-1, 23-182, Tyr-160/Tyr-171, MOD:00048." [PRO:CNA]
Yes
Yes
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CD3G forms found in complexes   

CD3G Component
 Complexes
PR:000025779 CD3G/iso:1/SigPep-/Phos:1 PR:000025781 CD3 epsilon:CD3 gamma with phosphorylated ITAM
PR:000025780 hCD3G/iso:1/SigPep-/Phos:1 PR:000025782 CD3 epsilon:CD3 gamma with phosphorylated ITAM (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025780 hCD3G/iso:1/SigPep-/Phos:1
UniProtKB:P09693-1, 23-182, Tyr-160/Tyr-171, MOD:00048		 located_inGO:0005886 plasma membrane Reactome:REACT_13072