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Protein Ontology report - integrin alpha with A domain
PR:000001005 - http://purl.obolibrary.org/obo/PR_000001005
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000001005   
  PRO nameintegrin alpha with A domain 
  Synonyms
Other: EXACT:integrin alpha with I domain
  Definition"An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage." [PIRSF:PIRSF002497] 
  PRO Categoryfamily 
  ParentPR:000025796 integrin alpha
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene9                                                  Organism-Gene 20                                        
         Sequence1                                                  Organism-Sequence 15                                        
         Modification6                                                  Organism-Modification 45                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF002497
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000001005 integrin alpha with A domain
CD4

gene


PR:000001007 integrin alpha-1
ITGA1

organism-gene


PR:E1C0V6 integrin alpha-1 (chicken)
chick-ITGA1

organism-gene


PR:P18614 integrin alpha-1 (rat)
rITGA1

organism-modification


PR:000058808 integrin alpha-1 N-glycosylated 1 (rat)
rITGA1/NGlyco:1

organism-modification


PR:000058809 integrin alpha-1 N-glycosylated 2 (rat)
rITGA1/NGlyco:2

organism-modification


PR:000058810 integrin alpha-1 N-glycosylated 3 (rat)
rITGA1/NGlyco:3

organism-gene


PR:P56199 integrin alpha-1 (human)
hITGA1

organism-modification


PR:000048056 integrin alpha-1, signal peptide removed form (human)
hITGA1/SigPep-

organism-gene


PR:Q3V3R4 integrin alpha-1 (mouse)
mITGA1

gene


PR:000001008 integrin alpha-2
ITGA2

organism-gene


PR:P17301 integrin alpha-2 (human)
hITGA2

organism-modification


PR:000048059 integrin alpha-2, signal peptide removed form (human)
hITGA2/SigPep-

organism-modification


PR:000055938 integrin alpha-2 N-glycosylated 1 (human)
hITGA2/NGlyco:1

organism-modification


PR:000055939 integrin alpha-2 N-glycosylated 2 (human)
hITGA2/NGlyco:2

organism-modification


PR:000055940 integrin alpha-2 N-glycosylated 3 (human)
hITGA2/NGlyco:3

organism-modification


PR:000055941 integrin alpha-2 N-glycosylated 4 (human)
hITGA2/NGlyco:4

organism-modification


PR:000055942 integrin alpha-2 N-glycosylated 5 (human)
hITGA2/NGlyco:5

organism-modification


PR:000074180 integrin alpha-2 deaminated 1 (human)
hITGA2/Deam:1

organism-modification


PR:000085672 integrin alpha-2 deaminated 2 (human)
hITGA2/Deam:2

organism-gene


PR:Q62469 integrin alpha-2 (mouse)
mITGA2

modification


PR:000018308 integrin alpha-2, signal peptide removed form
ITGA2/SigPep-

organism-modification


PR:000048059 integrin alpha-2, signal peptide removed form (human)
hITGA2/SigPep-

gene


PR:000001009 integrin alpha-D
ITGAD

organism-gene


PR:Q13349 integrin alpha-D (human)
hITGAD

organism-modification


PR:000048066 integrin alpha-D, signal peptide removed form (human)
hITGAD/SigPep-

organism-gene


PR:Q3V0T4 integrin alpha-D (mouse)
mITGAD

gene


PR:000001010 integrin alpha-E
ITGAE

organism-gene


PR:P38570 integrin alpha-E (human)
hITGAE

organism-modification


PR:000026869 integrin alpha-E, signal peptide removed form (human)
hITGAE/SigPep-

organism-modification


PR:000065650 integrin alpha-E phosphorylated 1 (human)
hITGAE/Phos:1

organism-gene


PR:Q60677 integrin alpha-E (mouse)
mITGAE

modification


PR:000018310 integrin alpha-E, signal peptide removed form
ITGAE/SigPep-

organism-modification


PR:000026869 integrin alpha-E, signal peptide removed form (human)
hITGAE/SigPep-

modification


PR:000018311 integrin alpha-E proteolytic cleavage product
ITGAE/ClvPrd

gene


PR:000001011 integrin alpha-L
ITGAL

organism-gene


PR:P20701 integrin alpha-L (human)
hITGAL

organism-sequence


PR:P20701-1 integrin alpha-L isoform h1 (human)
hITGAL/iso:h1

organism-sequence


PR:P20701-2 integrin alpha-L isoform h2 (human)
hITGAL/iso:h2

organism-sequence


PR:P20701-3 integrin alpha-L isoform h3 (human)
hITGAL/iso:h3

organism-modification


PR:000028414 integrin alpha-L, signal peptide removed form (human)
hITGAL/SigPep-

Yes
organism-modification


PR:000067504 integrin alpha-L methylated 1 (human)
hITGAL/Me:1

organism-modification


PR:000075596 integrin alpha-L deaminated 1 (human)
hITGAL/Deam:1

organism-modification


PR:000075999 integrin alpha-L cysteinylated 1 (human)
hITGAL/Cyst:1

organism-modification


PR:000076345 integrin alpha-L deaminated 2 (human)
hITGAL/Deam:2

organism-modification


PR:000078384 integrin alpha-L glutathionylated 1 (human)
hITGAL/SGlt:1

organism-modification


PR:000080133 integrin alpha-L methylated 2 (human)
hITGAL/Me:2

organism-modification


PR:000081450 integrin alpha-L cysteinylated 2 (human)
hITGAL/Cyst:2

organism-modification


PR:000081773 integrin alpha-L deaminated 3 (human)
hITGAL/Deam:3

organism-gene


PR:P24063 integrin alpha-L (mouse)
mITGAL

organism-sequence


PR:P24063-1 integrin alpha-L isoform m1 (mouse)
mITGAL/iso:m1

organism-sequence


PR:P24063-2 integrin alpha-L isoform m2 (mouse)
mITGAL/iso:m2

organism-modification


PR:000068662 integrin alpha-L deaminated 1 (mouse)
mITGAL/Deam:1

organism-modification


PR:000070115 integrin alpha-L cysteinylated 1 (mouse)
mITGAL/Cyst:1

modification


PR:000018313 integrin alpha-L, signal peptide removed form
ITGAL/SigPep-

organism-modification


PR:000028414 integrin alpha-L, signal peptide removed form (human)
hITGAL/SigPep-

Yes
gene


PR:000001012 integrin alpha-M
ITGAM

organism-gene


PR:P05555 integrin alpha-M (mouse)
mITGAM

organism-sequence


PR:P05555-1 integrin alpha-M isoform m1 (mouse)
mITGAM/iso:m1

organism-sequence


PR:P05555-2 integrin alpha-M isoform m2 (mouse)
mITGAM/iso:m2

organism-gene


PR:P11215 integrin alpha-M (human)
hITGAM

organism-sequence


PR:P11215-1 integrin alpha-M isoform h1 (human)
hITGAM/iso:h1

organism-sequence


PR:P11215-2 integrin alpha-M isoform h2 (human)
hITGAM/iso:h2

organism-modification


PR:000027393 integrin alpha-M, signal peptide removed form (human)
hITGAM/SigPep-

Yes
organism-modification


PR:000065849 integrin alpha-M cysteinylated 1 (human)
hITGAM/Cyst:1

organism-modification


PR:000066531 integrin alpha-M deaminated 1 (human)
hITGAM/Deam:1

organism-modification


PR:000069121 integrin alpha-M deaminated 2 (human)
hITGAM/Deam:2

organism-modification


PR:000071155 integrin alpha-M deaminated 3 (human)
hITGAM/Deam:3

organism-modification


PR:000072678 integrin alpha-M deaminated 4 (human)
hITGAM/Deam:4

organism-modification


PR:000076367 integrin alpha-M deaminated 5 (human)
hITGAM/Deam:5

organism-modification


PR:000079184 integrin alpha-M cysteinylated 2 (human)
hITGAM/Cyst:2

organism-modification


PR:000081774 integrin alpha-M cysteinylated 3 (human)
hITGAM/Cyst:3

organism-gene


PR:Q9QYE7 integrin alpha-D (rat)
rITGAM

modification


PR:000018315 integrin alpha-M, signal peptide removed form
ITGAM/SigPep-

organism-modification


PR:000027393 integrin alpha-M, signal peptide removed form (human)
hITGAM/SigPep-

Yes
gene


PR:000001013 integrin alpha-X
ITGAX

organism-gene


PR:P20702 integrin alpha-X (human)
hITGAX

organism-modification


PR:000048068 integrin alpha-X, signal peptide removed form (human)
hITGAX/SigPep-

organism-modification


PR:000067455 integrin alpha-X deaminated 1 (human)
hITGAX/Deam:1

organism-modification


PR:000072290 integrin alpha-X phosphorylated 1 (human)
hITGAX/Phos:1

organism-modification


PR:000072421 integrin alpha-X deaminated 2 (human)
hITGAX/Deam:2

organism-modification


PR:000079771 integrin alpha-X deaminated 3 (human)
hITGAX/Deam:3

organism-modification


PR:000082347 integrin alpha-X cysteinylated 1 (human)
hITGAX/Cyst:1

organism-gene


PR:Q9QXH4 integrin alpha-X (mouse)
mITGAX

organism-modification


PR:000067248 integrin alpha-X cysteinylated 1 (mouse)
mITGAX/Cyst:1

modification


PR:000018317 integrin alpha-X, signal peptide removed form
ITGAX/SigPep-

organism-modification


PR:000048068 integrin alpha-X, signal peptide removed form (human)
hITGAX/SigPep-

gene


PR:000009125 integrin alpha-10
ITGA10

organism-gene


PR:O75578 integrin alpha-10 (human)
hITGA10

organism-sequence


PR:O75578-1 integrin alpha-10 isoform h1 (human)
hITGA10/iso:h1

organism-sequence


PR:O75578-2 integrin alpha-10 isoform h2 (human)
hITGA10/iso:h2

organism-sequence


PR:O75578-3 integrin alpha-10 isoform h3 (human)
hITGA10/iso:h3

organism-modification


PR:000048057 integrin alpha-10, signal peptide removed form (human)
hITGA10/SigPep-

gene


PR:000009126 integrin alpha-11
ITGA11

organism-gene


PR:P61622 integrin alpha-11 (mouse)
mITGA11

organism-sequence


PR:P61622-1 integrin alpha-11 isoform 1 (mouse)
mITGA11/iso:1

organism-gene


PR:Q9UKX5 integrin alpha-11 (human)
hITGA11

organism-sequence


PR:Q9UKX5-1 integrin alpha-11 isoform 1 (human)
hITGA11/iso:1

organism-sequence


PR:Q9UKX5-2 integrin alpha-11 isoform h2 (human)
hITGA11/iso:h2

organism-modification


PR:000048058 integrin alpha-11, signal peptide removed form (human)
hITGA11/SigPep-

organism-modification


PR:000070107 integrin alpha-11 deaminated 1 (human)
hITGA11/Deam:1

sequence


PR:000043982 integrin alpha-11 isoform 1
ITGA11/iso:1

organism-sequence


PR:P61622-1 integrin alpha-11 isoform 1 (mouse)
mITGA11/iso:1

organism-sequence


PR:Q9UKX5-1 integrin alpha-11 isoform 1 (human)
hITGA11/iso:1

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CD4 forms found in complexes   

CD4 Component
 Complexes
PR:000027393 hITGAM/SigPep- PR:000027308 alphaM-beta2 integrin complex (human)
PR:000028431 integrin alphaMbeta2:JAM3 (human)
PR:000028414 hITGAL/SigPep- PR:000028447 LFA-1:JAM-A (human)