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Protein Ontology report - A-type voltage-gated potassium channel KCND2 isoform 1
PR:000000947 - http://purl.obolibrary.org/obo/PR_000000947
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000947   
  PRO nameA-type voltage-gated potassium channel KCND2 isoform 1 
  Synonyms
PRO-Short-label: EXACT:KCND2/iso:1
Other: EXACT:Kv4.2
  Definition"An A-type voltage-gated potassium channel KCND2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZV8-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000785 A-type voltage-gated potassium channel KCND2
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification5                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000947 A-type voltage-gated potassium channel KCND2 isoform 1
KCND2/iso:1

organism-sequence


PR:Q9NZV8-1 A-type voltage-gated potassium channel KCND2 isoform 1 (human)
hKCND2/iso:1
Yes
organism-sequence


PR:Q9Z0V2-1 A-type voltage-gated potassium channel KCND2 isoform 1 (mouse)
mKCND2/iso:1
Yes
organism-modification


PR:000036577 A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 1 (mouse)
mKCND2/iso:1/Phos:1

organism-modification


PR:000036578 A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2 (mouse)
mKCND2/iso:1/Phos:2
Yes
organism-modification


PR:000036579 A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3 (mouse)
mKCND2/iso:1/Phos:3
Yes
organism-modification


PR:000036580 A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 (mouse)
mKCND2/iso:1/Phos:4
Yes
organism-modification


PR:000045389 A-type voltage-gated potassium channel KCND2 isoform 1 unphosphorylated 3 (mouse)
mKCND2/iso:1/UnPhos:3
Yes
organism-modification


PR:000045390 A-type voltage-gated potassium channel KCND2 isoform 1 unphosphorylated 4 (mouse)
mKCND2/iso:1/UnPhos:4
Yes
modification


PR:000000988 A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated form
KCND2/iso:1/PhosRes+

modification


PR:000000994 A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 1
KCND2/iso:1/Phos:1

organism-modification


PR:000036577 A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 1 (mouse)
mKCND2/iso:1/Phos:1

modification


PR:000000995 A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2
KCND2/iso:1/Phos:2

organism-modification


PR:000036578 A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2 (mouse)
mKCND2/iso:1/Phos:2
Yes
modification


PR:000000996 A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3
KCND2/iso:1/Phos:3

organism-modification


PR:000036579 A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3 (mouse)
mKCND2/iso:1/Phos:3
Yes
modification


PR:000000997 A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4
KCND2/iso:1/Phos:4

organism-modification


PR:000036580 A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 (mouse)
mKCND2/iso:1/Phos:4
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0001508 action potentialPR:Q9NZV8-1 hKCND2/iso:1 PMID:11102480
GO:0007268 chemical synaptic transmissionPR:Q9NZV8-1 hKCND2/iso:1 PMID:11102480

Molecular Function GO Term
Protein Forms & Complexes
Evidence
contributes_to GO:0005250 A-type (transient outward) potassium channel activityPR:000045390 mKCND2/iso:1/UnPhos:4 PMID:16251476
decreased|contributes_to GO:0005250 A-type (transient outward) potassium channel activityPR:000036580 mKCND2/iso:1/Phos:4 PMID:16251476

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005783 endoplasmic reticulumPR:Q9Z0V2-1 mKCND2/iso:1 PMID:12829703
GO:0009986 cell surfacePR:000036580 mKCND2/iso:1/Phos:4 PMID:16251476
PR:000045389 mKCND2/iso:1/UnPhos:3 PMID:12829703; PMID:16251476
PR:Q9NZV8-1 hKCND2/iso:1 PMID:12493773
GO:0030425 dendritePR:000036578 mKCND2/iso:1/Phos:2 PMID:11040264
PR:000036579 mKCND2/iso:1/Phos:3 PMID:11040264
PR:000036580 mKCND2/iso:1/Phos:4 PMID:11040264