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Protein Ontology report - voltage-gated potassium channel subunit KCNA10
PR:000000809 - http://purl.obolibrary.org/obo/PR_000000809
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000809   
  PRO namevoltage-gated potassium channel subunit KCNA10 
  Synonyms
PRO-Short-label: EXACT:KCNA10
Other: EXACT:voltage-gated potassium channel subunit Kv1.8
  Definition"A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA10 gene or a 1:1 ortholog thereof. It is a subunit of the Kv1.8 channel is a delayed rectifier channel that may be involved in regulating the tone of renal vascular smooth muscle and may also participate in the cardiac action potential. It is regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. It can coassemble with other Kv1 subunits." [PMID:10836990
  PRO Categorygene 
  ParentPR:000000709 shaker-related voltage-gated potassium channel alpha subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:545
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000000809

voltage-gated potassium channel subunit KCNA10

KCNA10


"A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA10 gene or a 1:1 ortholog thereof. It is a subunit of the Kv1.8 channel is a delayed rectifier channel that may be involved in regulating the tone of renal vascular smooth muscle and may also participate in the cardiac action potential. It is regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. It can coassemble with other Kv1 subunits." [PMID:10836990]


organism-gene



PR:B2RQA1

potassium voltage-gated channel subfamily A member 10 (mouse)

mKCNA10


"A voltage-gated potassium channel subunit KCNA10 that is encoded in the genome of mouse." [OMA:B2RQA1, PRO:DNx]


organism-gene



PR:Q16322

potassium voltage-gated channel subfamily A member 10 (human)

hKCNA10


"A voltage-gated potassium channel subunit KCNA10 that is encoded in the genome of human." []


organism-sequence



PR:Q16322-1

potassium voltage-gated channel subfamily A member 10 isoform 1 (human)

hKCNA10/iso:1


"A voltage-gated potassium channel subunit KCNA10 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-gene



PR:Q7T199

potassium voltage-gated channel subfamily A member 10 (chicken)

chick-KCNA10


"A voltage-gated potassium channel subunit KCNA10 that is encoded in the genome of chicken." [PRO:DNx, UniProtKB:Q7T199]


sequence



PR:000000971

voltage-gated potassium channel subunit KCNA10 isoform 1

KCNA10/iso:1


"A voltage-gated potassium channel subunit KCNA10 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16322-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q16322-1

potassium voltage-gated channel subfamily A member 10 isoform 1 (human)

hKCNA10/iso:1


"A voltage-gated potassium channel subunit KCNA10 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q16322-1 hKCNA10/iso:1 enablescontributes_to GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity PMID:10836990; PMID:9177773
contributes_to GO:0005251 delayed rectifier potassium channel activity PMID:10836990
located_inGO:0008076 voltage-gated potassium channel complex PMID:12060596