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RACE-PRO
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Protein Ontology report - TGF-beta 2 isoform A cleaved 3
PR:000000631 -
http://purl.obolibrary.org/obo/PR_000000631
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000631
PRO name
TGF-beta 2 isoform A cleaved 3
Synonyms
PRO-Short-label
:
EXACT:
TGFB2/iso:A/Clv:3
Definition
"A TGF-beta 2 isoform A, signal peptide removed form that has been processed by subsequent cleavage at the dibasic cleavage site rendering the latency associated peptide (LAP) and the mature protein non-covalently bound." [
PMID:10224129
]
PRO Category
modification
Parent
PR:000018293
TGF-beta 2 proteolytic cleavage product
PR:000021908
TGF-beta 2 isoform A, signal peptide removed form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000000631
TGF-beta 2 isoform A cleaved 3
TGFB2/iso:A/Clv:3
"A TGF-beta 2 isoform A, signal peptide removed form that has been processed by subsequent cleavage at the dibasic cleavage site rendering the latency associated peptide (LAP) and the mature protein non-covalently bound." [PMID:10224129]
organism-modification
PR:000036533
TGF-beta 2 isoform A cleaved 3 (human)
hTGFB2/iso:A/Clv:3
"A TGF-beta 2 isoform A cleaved 3 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P61812-1, 20-302, 303-414." [PMID:3162913, PMID:3476488, PRO:CNA]
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036533
hTGFB2/iso:A/Clv:3
UniProtKB:P61812-1, 20-302, 303-414
enables
GO:0042803
protein homodimerization activity
PMID:3476488
located_in
GO:0005615
extracellular space
PMID:3162913
