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Protein Ontology report - GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1
PR:000000615 - http://purl.obolibrary.org/obo/PR_000000615
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000615   
  PRO nameGTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 
  Synonyms
PRO-Short-label: EXACT:RHOA/iso:1/IpCysEst:1
  Definition"A GTP-binding protein RhoA isoform 1 that has been geranylgeranylated on the Cys residue within the C-terminal CaaX motif (a=an aliphatic residue, X=any residue), followed by cleavage of aaX and methylation of the Cys. Example: UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119." [PMID:16773203, PMID:1905729, PRO:CNA] 
  PRO Categorymodification 
  ParentPR:000000395 GTP-binding protein RhoA isoform 1
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000000615 GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1
RHOA/iso:1/IpCysEst:1

organism-modification


PR:000036520 GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 (human)
hRHOA/iso:1/IpCysEst:1
Yes
organism-modification


PR:000036521 GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 (cow)
cow-RHOA/iso:1/IpCysEst:1
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0030036 actin cytoskeleton organizationPR:000036520 hRHOA/iso:1/IpCysEst:1 PMID:16773203
GO:0043123 positive regulation of canonical NF-kappaB signal transductionPR:000036520 hRHOA/iso:1/IpCysEst:1 PMID:12761501
GO:1901224 positive regulation of non-canonical NF-kappaB signal transductionPR:000036520 hRHOA/iso:1/IpCysEst:1 PMID:12761501

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005886 plasma membranePR:000036520 hRHOA/iso:1/IpCysEst:1 PMID:16773203
PR:000036521 cow-RHOA/iso:1/IpCysEst:1 PMID:1903193