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gene
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PR:000000364 |
smad2
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SMAD2
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"A TGF-beta receptor-regulated smad protein that is a translation product of the human SMAD2 gene or a 1:1 ortholog thereof." [PMID:9311995]
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organism-gene
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PR:O70436 |
mothers against decapentaplegic homolog 2 (rat)
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rSMAD2
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"A smad2 that is encoded in the genome of rat." [OMA:O70436, PRO:DNx]
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organism-gene
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PR:P45896 |
dwarfin sma-3 (worm)
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SMAD2 (worm)
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"A smad2 that is encoded in the genome of worm." [OMA:P45896, PRO:DNx]
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organism-gene
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PR:Q15796 |
mothers against decapentaplegic homolog 2 (human)
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hSMAD2
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"A smad2 that is encoded in the genome of human." []
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organism-sequence
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PR:000000470 |
smad2 sequence variant R133C (human)
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hSMAD2/var:R133C
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"A mothers against decapentaplegic homolog 2 (human) that has a Cys residue at the position equivalent to Arg-133 of the amino acid sequence represented by UniProtKB:Q15796-1. Example: UniProtKB:Q15796-1, Arg-133, CHEBI:29950." [PMID:8752209, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000471 |
smad2 sequence variant L440R (human)
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hSMAD2/var:L440R
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"A mothers against decapentaplegic homolog 2 (human) that has an Arg residue at the position equivalent to Leu-440 of the amino acid sequence represented by UniProtKB:Q15796-1. Example: UniProtKB:Q15796-1, Leu-440, CHEBI:29952." [PMID:8752209, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000472 |
smad2 sequence variant P445H (human)
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hSMAD2/var:P445H
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"A mothers against decapentaplegic homolog 2 (human) that has a His residue at the position equivalent to Pro-445 of the amino acid sequence represented by UniProtKB:Q15796-1. Example: UniProtKB:Q15796-1, Pro-445, CHEBI:29979." [PMID:8752209, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000473 |
smad2 sequence variant D450E (human)
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hSMAD2/var:D450E
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"A mothers against decapentaplegic homolog 2 (human) that has a Glu residue at the position equivalent to Asp-450 of the amino acid sequence represented by UniProtKB:Q15796-1. Example: UniProtKB:Q15796-1, Asp-450, CHEBI:29972." [PMID:8752209, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000474 |
smad2 sequence variant 5 (human)
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hSMAD2/var:5
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"A mothers against decapentaplegic homolog 2 (human) that has a fifteen-residue deletion at the position equivalent to region 344-358 of the amino acid sequence represented by UniProtKB:Q15796-1. Example: UniProtKB:Q15796-1, 2-343, 359-467." [PMID:8673135, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:Q15796-1 |
mothers against decapentaplegic homolog 2 isoform Long (human)
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hSMAD2/iso:Long
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"A smad2 isoform Long that is encoded in the genome of human." [PRO:CNA]
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organism-modification
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PR:000025934 |
smad2 isoform Long phosphorylated 1 (human)
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hSMAD2/iso:Long/Phos:1
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"A smad2 isoform Long phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046." [PMID:8980228, PMID:9346966]
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Yes |
Yes |
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organism-modification
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PR:000025935 |
smad2 isoform Long phosphorylated 2 (human)
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hSMAD2/iso:Long/Phos:2
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"A smad2 isoform Long phosphorylated 2 in human. This form is phosphorylated at the N-terminal Px[ST]P motif, multiple Ser and/or Thr residues in the linker region and the SSxS C-terminal motif. Example: UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046." [PMID:12193595]
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Yes |
Yes |
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organism-modification
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PR:000025936 |
smad2 isoform Long phosphorylated 3 (human)
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hSMAD2/iso:Long/Phos:3
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"A smad2 isoform Long phosphorylated 3 in human. This form is phosphorylated on a [S/T] residue within the MH1-MH2 domain linker region, in addition to the two last Ser residues of the SSxS C-terminal motif. UniProtKB:Q15796-1, Ser-240/Ser-465/Ser-467, MOD:00046." [PMID:11027280]
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Yes |
Yes |
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organism-modification
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PR:000025937 |
smad2 isoform Long phosphorylated 4 (human)
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hSMAD2/iso:Long/Phos:4
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"A smad2 isoform Long phosphorylated 4 in human. This form is phosphorylated at the clusters of [S/T]P motifs within the MH1-MH2 domain linker region. UniProtKB:Q15796-1, Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255, MOD:00046." [PMID:10197981]
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Yes |
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organism-modification
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PR:000036554 |
smad2 isoform Long acetylated and phosphorylated 1 (human)
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hSMAD2/iso:Long/AcPhos:1
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"A smad2 isoform Long acetylated and phosphorylated 1 in human. UniProtKB:Q15796-1, Lys-19, MOD:00064|Ser-465/Ser-467, MOD:00046." [PMID:17074756, PRO:CNA]
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Yes |
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organism-modification
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PR:000045371 |
smad2 isoform Long unphosphorylated 1 (human)
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hSMAD2/iso:Long/UnPhos:1
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"A mothers against decapentaplegic homolog 2 isoform Long (human) that lacks phosphorylation on the two last Ser of the C-terminal SSxS motif in human. UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291." [PRO:CNA]
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Yes |
Yes |
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organism-sequence
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PR:Q15796-2 |
mothers against decapentaplegic homolog 2 isoform Short (human)
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hSMAD2/iso:Short
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"A smad2 isoform Short that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15796]
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organism-modification
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PR:000025938 |
smad2 isoform Short phosphorylated 1 (human)
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hSMAD2/iso:Short/Phos:1
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"A smad2 isoform Short phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046." [PRO:CNA]
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Yes |
Yes |
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organism-modification
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PR:000036556 |
smad2 isoform Short acetylated and phosphorylated 1 (human)
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hSMAD2/iso:Short/AcPhos:1
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"A smad2 isoform Short acetylated and phosphorylated 1 in human. UniProtKB:Q15796-2, Lys-19, MOD:00064|Ser-435/Ser-437, MOD:00046." [PMID:17074756, PRO:CNA]
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Yes |
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organism-modification
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PR:000045494 |
smad2 isoform Short unphosphorylated 1 (human)
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hSMAD2/iso:Short/UnPhos:1
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"A mothers against decapentaplegic homolog 2 isoform Short (human) that lacks phosphorylation on the last two Ser of the C-terminal SSxS motif. UniProtKB:Q15796-2, Ser-435/Ser-437, PR:000026291." [PRO:CNA]
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organism-modification
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PR:000025960 |
smad2 isoform unphosphorylated 1 (human)
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hSMAD2/iso:[Long/Short]/UnPhos:1
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"A mothers against decapentaplegic homolog 2 (human) that lacks phosphorylation on the last two Ser of the C-terminal SSxS motif." [PMID:19135894, PRO:CNA, PRO:DAN]
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organism-modification
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PR:000045371 |
smad2 isoform Long unphosphorylated 1 (human)
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hSMAD2/iso:Long/UnPhos:1
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"A mothers against decapentaplegic homolog 2 isoform Long (human) that lacks phosphorylation on the two last Ser of the C-terminal SSxS motif in human. UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291." [PRO:CNA]
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organism-modification
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PR:000045494 |
smad2 isoform Short unphosphorylated 1 (human)
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hSMAD2/iso:Short/UnPhos:1
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"A mothers against decapentaplegic homolog 2 isoform Short (human) that lacks phosphorylation on the last two Ser of the C-terminal SSxS motif. UniProtKB:Q15796-2, Ser-435/Ser-437, PR:000026291." [PRO:CNA]
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organism-modification
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PR:000049281 |
mothers against decapentaplegic homolog 2, initiator methionine removed form (human)
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hSMAD2/InitMet-
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"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed. UniProtKB:Q15796, 2-467." [PRO:DNx, Reactome:R-HSA-3006352, Reactome:R-HSA-3006353]
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organism-modification
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PR:000049282 |
mothers against decapentaplegic homolog 2, initiator methionine removed phosphorylated 1 (human)
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hSMAD2/InitMet-/Phos:1
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"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 465 and 467 of the amino acid sequence represented by UniProtKB:Q15796. UniProtKB:Q15796, 2-467, Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3009185, Reactome:R-HSA-3009186]
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organism-modification
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PR:000049283 |
mothers against decapentaplegic homolog 2, initiator methionine removed phosphorylated 5 (human)
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hSMAD2/InitMet-/Phos:5
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"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 220, and phosphoserine at positions 465 and 467 of the amino acid sequence represented by UniProtKB:Q15796. UniProtKB:Q15796, 2-467, Thr-220, MOD:00047|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3009189]
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organism-modification
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PR:000049284 |
mothers against decapentaplegic homolog 2, initiator methionine removed ubiquitinated form (human)
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hSMAD2/InitMet-/UbiqLys+
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"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed and that includes at least one ubiquitinated lysine. UniProtKB:Q15796, 2-467, MOD:01148." [PRO:DNx, Reactome:R-HSA-6782774]
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organism-modification
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PR:000064775 |
mothers against decapentaplegic homolog 2, initiator methionine removed phosphorylated and ubiquitinated 1 (human)
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hSMAD2/InitMet-/PhosUbiq:1
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"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed, that has been phosphorylated on the residues at the positions equivalent to Thr-220, Ser-465, and Ser-467 of the amino acid sequence represented by UniProtKB:Q15796-1, and that includes at least one ubiquitinated lysine. Example: UniProtKB:Q15796-1, 2-467, Thr-220, MOD:00047|Ser-465/Ser-467, MOD:00046|MOD:01148." [PRO:DNx, Reactome:R-HSA-9773843]
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organism-modification
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PR:000060357 |
mothers against decapentaplegic homolog 2 sequence variant D300A, initiator methionine removed phosphorylated 1 (human)
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hSMAD2/var:D300A/InitMet-/Phos:1
|
"A mothers against decapentaplegic homolog 2 (human) that has an Ala residue at the position equivalent to Asp-300 of the amino acid sequence represented by UniProtKB:Q15796-1, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-465 and Ser-467. Example: UniProtKB:Q15796-1, 2-467, Asp-300, CHEBI:46217|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315064]
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organism-modification
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PR:000060522 |
mothers against decapentaplegic homolog 2 sequence variant S464L, initiator methionine removed form (human)
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hSMAD2/var:S464L/InitMet-
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"A mothers against decapentaplegic homolog 2 (human) that has a Leu residue at the position equivalent to Ser-464 of the amino acid sequence represented by UniProtKB:Q15796-1 and that has had the initiator methionine removed. Example: UniProtKB:Q15796-1, 2-467, Ser-464, CHEBI:30006." [PRO:DNx, Reactome:R-HSA-3304383]
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organism-modification
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PR:000060657 |
mothers against decapentaplegic homolog 2 sequence variant D300V, initiator methionine removed phosphorylated 1 (human)
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hSMAD2/var:D300V/InitMet-/Phos:1
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"A mothers against decapentaplegic homolog 2 (human) that has a Val residue at the position equivalent to Asp-300 of the amino acid sequence represented by UniProtKB:Q15796-1, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-465 and Ser-467. Example: UniProtKB:Q15796-1, 2-467, Asp-300, CHEBI:30015|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315067]
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organism-modification
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PR:000060862 |
mothers against decapentaplegic homolog 2 sequence variant D300N, initiator methionine removed phosphorylated 1 (human)
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hSMAD2/var:D300N/InitMet-/Phos:1
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"A mothers against decapentaplegic homolog 2 (human) that has an Asn residue at the position equivalent to Asp-300 of the amino acid sequence represented by UniProtKB:Q15796-1, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-465 and Ser-467. Example: UniProtKB:Q15796-1, 2-467, Asp-300, CHEBI:50347|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315066]
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organism-modification
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PR:000061944 |
mothers against decapentaplegic homolog 2 sequence variant A354T, initiator methionine removed phosphorylated 1 (human)
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hSMAD2/var:A354T/InitMet-/Phos:1
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"A mothers against decapentaplegic homolog 2 (human) that has a Thr residue at the position equivalent to Ala-354 of the amino acid sequence represented by UniProtKB:Q15796-1, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-465 and Ser-467. Example: UniProtKB:Q15796-1, 2-467, Ala-354, CHEBI:30013|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315474]
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organism-modification
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PR:000062120 |
mothers against decapentaplegic homolog 2 sequence variant P305Q, initiator methionine removed phosphorylated 1 (human)
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hSMAD2/var:P305Q/InitMet-/Phos:1
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"A mothers against decapentaplegic homolog 2 (human) that has a Gln residue at the position equivalent to Pro-305 of the amino acid sequence represented by UniProtKB:Q15796-1, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-465 and Ser-467. Example: UniProtKB:Q15796-1, 2-467, Pro-305, CHEBI:30011|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315070]
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organism-modification
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PR:000062419 |
mothers against decapentaplegic homolog 2, initiator methionine removed phosphorylated 2 (human)
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hSMAD2/InitMet-/Phos:2
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"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-250 of the amino acid sequence represented by UniProtKB:Q15796-1. Example: UniProtKB:Q15796-1, 2-467, Ser-250, MOD:00046." [PRO:DNx, Reactome:R-HSA-9731121]
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organism-modification
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PR:000063661 |
mothers against decapentaplegic homolog 2 sequence variant S464*, initiator methionine removed form (human)
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hSMAD2/var:S464*/InitMet-
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"A mothers against decapentaplegic homolog 2 (human) that has has been truncated after the position equivalent to Cys-463 of the amino acid sequence represented by UniProtKB:Q15796-1 and that has had the initiator methionine removed. Example: UniProtKB:Q15796-1, 2-463." [PRO:DNx, Reactome:R-HSA-3304362]
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organism-modification
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PR:000063912 |
mothers against decapentaplegic homolog 2 sequence variant S467P, initiator methionine removed form (human)
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hSMAD2/var:S467P/InitMet-
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"A mothers against decapentaplegic homolog 2 (human) that has a Pro residue at the position equivalent to Ser-467 of the amino acid sequence represented by UniProtKB:Q15796-1 and that has had the initiator methionine removed. Example: UniProtKB:Q15796-1, 2-467, Ser-467, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-3304375]
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organism-modification
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PR:000064349 |
mothers against decapentaplegic homolog 2 sequence variant P305L, initiator methionine removed phosphorylated 1 (human)
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hSMAD2/var:P305L/InitMet-/Phos:1
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"A mothers against decapentaplegic homolog 2 (human) that has a Leu residue at the position equivalent to Pro-305 of the amino acid sequence represented by UniProtKB:Q15796-1, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-465 and Ser-467. Example: UniProtKB:Q15796-1, 2-467, Pro-305, CHEBI:30006|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315471]
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organism-modification
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PR:000049284 |
mothers against decapentaplegic homolog 2, initiator methionine removed ubiquitinated form (human)
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hSMAD2/InitMet-/UbiqLys+
|
"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed and that includes at least one ubiquitinated lysine. UniProtKB:Q15796, 2-467, MOD:01148." [PRO:DNx, Reactome:R-HSA-6782774]
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organism-modification
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PR:000064775 |
mothers against decapentaplegic homolog 2, initiator methionine removed phosphorylated and ubiquitinated 1 (human)
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hSMAD2/InitMet-/PhosUbiq:1
|
"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed, that has been phosphorylated on the residues at the positions equivalent to Thr-220, Ser-465, and Ser-467 of the amino acid sequence represented by UniProtKB:Q15796-1, and that includes at least one ubiquitinated lysine. Example: UniProtKB:Q15796-1, 2-467, Thr-220, MOD:00047|Ser-465/Ser-467, MOD:00046|MOD:01148." [PRO:DNx, Reactome:R-HSA-9773843]
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organism-modification
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PR:000050145 |
smad2 phosphorylated 1 (human)
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hSMAD2/Phos:1
|
"A smad2 phosphorylated 1 in human. This form is phosphorylated in the last two Ser of the C-terminal SSxS motif. UniProtKB:Q15796, Ser-465/Ser-467, MOD:00046." [PMID:8980228, PMID:9346966]
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organism-modification
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PR:000065797 |
mothers against decapentaplegic homolog 2 methylated 1 (human)
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hSMAD2/Me:1
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"A mothers against decapentaplegic homolog 2 (human) that has been methylated on the residue at the position equivalent to Cys-81 of the amino acid sequence represented by UniProtKB:Q15796-1. Example: UniProtKB:Q15796-1, Cys-81, MOD:00660." [IEDB_epitope:1021722, IEDB_epitope:1059624, PRO:DNx]
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organism-modification
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PR:000077056 |
mothers against decapentaplegic homolog 2 cysteinylated 1 (human)
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hSMAD2/Cyst:1
|
"A mothers against decapentaplegic homolog 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-161 of the amino acid sequence represented by UniProtKB:Q15796-1. Example: UniProtKB:Q15796-1, Cys-161, MOD:00765." [IEDB_epitope:925064, PRO:DNx]
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organism-gene
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PR:Q62432 |
mothers against decapentaplegic homolog 2 (mouse)
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mSMAD2
|
"A smad2 that is encoded in the genome of mouse." [OMA:Q62432, PRO:DNx]
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organism-sequence
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PR:Q62432-1 |
mothers against decapentaplegic homolog 2 isoform Long (mouse)
|
mSMAD2/iso:Long
|
"A smad2 isoform Long that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
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organism-modification
|
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PR:000025942 |
smad2 isoform Long phosphorylated 1 (mouse)
|
mSMAD2/iso:Long/Phos:1
|
"A smad2 isoform Long phosphorylated 1 in mouse. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046." [PMID:8980228, PMID:9346966]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000036482 |
smad2 isoform Long phosphorylated and ubiquitinated form (mouse)
|
mSMAD2/iso:Long/PhosUbiq+
|
"A smad2 isoform Long phosphorylated and ubiquitinated form in mouse. UniProtKB:Q62432-1, MOD:00696|MOD:01148." [PMID:15496141, PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036555 |
smad2 isoform Long phosphorylated and ubiquitinated 1 (mouse)
|
mSMAD2/iso:Long/PhosUbiq:1
|
"A smad2 isoform Long phosphorylated and ubiquitinated 1 in mouse. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148." [PMID:15496141, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
organism-sequence
|
|
PR:Q62432-2 |
mothers against decapentaplegic homolog 2 isoform Short (mouse)
|
mSMAD2/iso:Short
|
"A smad2 isoform Short that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q62432]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000025943 |
smad2 isoform Short phosphorylated 1 (mouse)
|
mSMAD2/iso:Short/Phos:1
|
"A smad2 isoform Short phosphorylated 1 in mouse. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q62432-2, Ser-435/Ser-437, MOD:00046." [PRO:CNA]
|
Yes |
Yes |
|
|
|
|
| | | | |
| | | | | | |
organism-gene
|
|
PR:Q9I9P9 |
mothers against decapentaplegic homolog 2 (zebrafish)
|
z-SMAD2
|
"A smad2 that is encoded in the genome of zebrafish." [PRO:DNx, UniProtKB:Q9I9P9]
|
|
|
|
|
|
|
| | | | |
| | | | | | |
sequence
|
|
PR:000000468 |
smad2 isoform Long
|
SMAD2/iso:Long
|
"A smad2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15796-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-sequence
|
|
PR:Q15796-1 |
mothers against decapentaplegic homolog 2 isoform Long (human)
|
hSMAD2/iso:Long
|
"A smad2 isoform Long that is encoded in the genome of human." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000025934 |
smad2 isoform Long phosphorylated 1 (human)
|
hSMAD2/iso:Long/Phos:1
|
"A smad2 isoform Long phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046." [PMID:8980228, PMID:9346966]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000025935 |
smad2 isoform Long phosphorylated 2 (human)
|
hSMAD2/iso:Long/Phos:2
|
"A smad2 isoform Long phosphorylated 2 in human. This form is phosphorylated at the N-terminal Px[ST]P motif, multiple Ser and/or Thr residues in the linker region and the SSxS C-terminal motif. Example: UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046." [PMID:12193595]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000025936 |
smad2 isoform Long phosphorylated 3 (human)
|
hSMAD2/iso:Long/Phos:3
|
"A smad2 isoform Long phosphorylated 3 in human. This form is phosphorylated on a [S/T] residue within the MH1-MH2 domain linker region, in addition to the two last Ser residues of the SSxS C-terminal motif. UniProtKB:Q15796-1, Ser-240/Ser-465/Ser-467, MOD:00046." [PMID:11027280]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000025937 |
smad2 isoform Long phosphorylated 4 (human)
|
hSMAD2/iso:Long/Phos:4
|
"A smad2 isoform Long phosphorylated 4 in human. This form is phosphorylated at the clusters of [S/T]P motifs within the MH1-MH2 domain linker region. UniProtKB:Q15796-1, Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255, MOD:00046." [PMID:10197981]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000036554 |
smad2 isoform Long acetylated and phosphorylated 1 (human)
|
hSMAD2/iso:Long/AcPhos:1
|
"A smad2 isoform Long acetylated and phosphorylated 1 in human. UniProtKB:Q15796-1, Lys-19, MOD:00064|Ser-465/Ser-467, MOD:00046." [PMID:17074756, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000045371 |
smad2 isoform Long unphosphorylated 1 (human)
|
hSMAD2/iso:Long/UnPhos:1
|
"A mothers against decapentaplegic homolog 2 isoform Long (human) that lacks phosphorylation on the two last Ser of the C-terminal SSxS motif in human. UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291." [PRO:CNA]
|
Yes |
Yes |
|
|
|
|
| | | | | | |
| | | | |
organism-sequence
|
|
PR:Q62432-1 |
mothers against decapentaplegic homolog 2 isoform Long (mouse)
|
mSMAD2/iso:Long
|
"A smad2 isoform Long that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000025942 |
smad2 isoform Long phosphorylated 1 (mouse)
|
mSMAD2/iso:Long/Phos:1
|
"A smad2 isoform Long phosphorylated 1 in mouse. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046." [PMID:8980228, PMID:9346966]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000036482 |
smad2 isoform Long phosphorylated and ubiquitinated form (mouse)
|
mSMAD2/iso:Long/PhosUbiq+
|
"A smad2 isoform Long phosphorylated and ubiquitinated form in mouse. UniProtKB:Q62432-1, MOD:00696|MOD:01148." [PMID:15496141, PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036555 |
smad2 isoform Long phosphorylated and ubiquitinated 1 (mouse)
|
mSMAD2/iso:Long/PhosUbiq:1
|
"A smad2 isoform Long phosphorylated and ubiquitinated 1 in mouse. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148." [PMID:15496141, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
modification
|
|
PR:000000572 |
smad2 isoform Long acetylated and phosphorylated form
|
SMAD2/iso:Long/AcPhos+
|
"A smad2 isoform Long that includes at least one acetylated residue and at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000649 |
smad2 isoform Long acetylated and phosphorylated 1
|
SMAD2/iso:Long/AcPhos:1
|
"A smad2 isoform Long acetylated and phosphorylated form in which the phosphorylation occurs upon TGF-beta receptor activation and which has been further acetylated on a Lys residue within the MH1 domain by coactivators, such as CBP, PCAF and EP300. Example: UniProtKB:Q15796-1, Lys-19, MOD:00064|Ser-465/Ser-467, MOD:00046." [PMID:17074756]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036554 |
smad2 isoform Long acetylated and phosphorylated 1 (human)
|
hSMAD2/iso:Long/AcPhos:1
|
"A smad2 isoform Long acetylated and phosphorylated 1 in human. UniProtKB:Q15796-1, Lys-19, MOD:00064|Ser-465/Ser-467, MOD:00046." [PMID:17074756, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
modification
|
|
PR:000000573 |
smad2 isoform Long phosphorylated and ubiquitinated form
|
SMAD2/iso:Long/PhosUbiq+
|
"A smad2 isoform Long that includes at least one phosphorylated residue and at least one ubiquitinated lysine." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000654 |
smad2 isoform Long phosphorylated and ubiquitinated 1
|
SMAD2/iso:Long/PhosUbiq:1
|
"A smad2 isoform Long phosphorylated and ubiquitinated form that has been phosphorylated by TGF-beta receptor activation and further ubiquitinated by NEDD4L. This form is targeted for proteosomal degradation. Example: UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148." [PMID:15496141]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036555 |
smad2 isoform Long phosphorylated and ubiquitinated 1 (mouse)
|
mSMAD2/iso:Long/PhosUbiq:1
|
"A smad2 isoform Long phosphorylated and ubiquitinated 1 in mouse. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148." [PMID:15496141, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000036482 |
smad2 isoform Long phosphorylated and ubiquitinated form (mouse)
|
mSMAD2/iso:Long/PhosUbiq+
|
"A smad2 isoform Long phosphorylated and ubiquitinated form in mouse. UniProtKB:Q62432-1, MOD:00696|MOD:01148." [PMID:15496141, PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036555 |
smad2 isoform Long phosphorylated and ubiquitinated 1 (mouse)
|
mSMAD2/iso:Long/PhosUbiq:1
|
"A smad2 isoform Long phosphorylated and ubiquitinated 1 in mouse. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148." [PMID:15496141, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
modification
|
|
PR:000000574 |
smad2 isoform Long phosphorylated form
|
SMAD2/iso:Long/PhosRes+
|
"A smad2 isoform Long that includes at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000572 |
smad2 isoform Long acetylated and phosphorylated form
|
SMAD2/iso:Long/AcPhos+
|
"A smad2 isoform Long that includes at least one acetylated residue and at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000649 |
smad2 isoform Long acetylated and phosphorylated 1
|
SMAD2/iso:Long/AcPhos:1
|
"A smad2 isoform Long acetylated and phosphorylated form in which the phosphorylation occurs upon TGF-beta receptor activation and which has been further acetylated on a Lys residue within the MH1 domain by coactivators, such as CBP, PCAF and EP300. Example: UniProtKB:Q15796-1, Lys-19, MOD:00064|Ser-465/Ser-467, MOD:00046." [PMID:17074756]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036554 |
smad2 isoform Long acetylated and phosphorylated 1 (human)
|
hSMAD2/iso:Long/AcPhos:1
|
"A smad2 isoform Long acetylated and phosphorylated 1 in human. UniProtKB:Q15796-1, Lys-19, MOD:00064|Ser-465/Ser-467, MOD:00046." [PMID:17074756, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000573 |
smad2 isoform Long phosphorylated and ubiquitinated form
|
SMAD2/iso:Long/PhosUbiq+
|
"A smad2 isoform Long that includes at least one phosphorylated residue and at least one ubiquitinated lysine." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000654 |
smad2 isoform Long phosphorylated and ubiquitinated 1
|
SMAD2/iso:Long/PhosUbiq:1
|
"A smad2 isoform Long phosphorylated and ubiquitinated form that has been phosphorylated by TGF-beta receptor activation and further ubiquitinated by NEDD4L. This form is targeted for proteosomal degradation. Example: UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148." [PMID:15496141]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036555 |
smad2 isoform Long phosphorylated and ubiquitinated 1 (mouse)
|
mSMAD2/iso:Long/PhosUbiq:1
|
"A smad2 isoform Long phosphorylated and ubiquitinated 1 in mouse. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148." [PMID:15496141, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036482 |
smad2 isoform Long phosphorylated and ubiquitinated form (mouse)
|
mSMAD2/iso:Long/PhosUbiq+
|
"A smad2 isoform Long phosphorylated and ubiquitinated form in mouse. UniProtKB:Q62432-1, MOD:00696|MOD:01148." [PMID:15496141, PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036555 |
smad2 isoform Long phosphorylated and ubiquitinated 1 (mouse)
|
mSMAD2/iso:Long/PhosUbiq:1
|
"A smad2 isoform Long phosphorylated and ubiquitinated 1 in mouse. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148." [PMID:15496141, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000650 |
smad2 isoform Long phosphorylated 1
|
SMAD2/iso:Long/Phos:1
|
"A smad2 isoform Long phosphorylated form in which the phosphorylation occurs at the last two Ser residues within the SSxS C-terminal motif by TGF-beta pathway activation. Example: UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046." [PMID:8980228, PMID:9346966]
|
|
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025934 |
smad2 isoform Long phosphorylated 1 (human)
|
hSMAD2/iso:Long/Phos:1
|
"A smad2 isoform Long phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046." [PMID:8980228, PMID:9346966]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025942 |
smad2 isoform Long phosphorylated 1 (mouse)
|
mSMAD2/iso:Long/Phos:1
|
"A smad2 isoform Long phosphorylated 1 in mouse. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046." [PMID:8980228, PMID:9346966]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000651 |
smad2 isoform Long phosphorylated 2
|
SMAD2/iso:Long/Phos:2
|
"A smad2 isoform Long phosphorylated form in which the phosphorylation occurs at the N-terminal Px[ST]P motif and multiple Ser and/or Thr residues in the linker region by ERK1. Example: UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046." [PMID:12193595]
|
|
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025935 |
smad2 isoform Long phosphorylated 2 (human)
|
hSMAD2/iso:Long/Phos:2
|
"A smad2 isoform Long phosphorylated 2 in human. This form is phosphorylated at the N-terminal Px[ST]P motif, multiple Ser and/or Thr residues in the linker region and the SSxS C-terminal motif. Example: UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046." [PMID:12193595]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000652 |
smad2 isoform Long phosphorylated 3
|
SMAD2/iso:Long/Phos:3
|
"A smad2 isoform Long phosphorylated form in which the phosphorylation occurs at a [S/T] residue within the MH1-MH2 domain linker region in response to decorin-induced Ca(2+) signaling." [PMID:11027280]
|
|
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025936 |
smad2 isoform Long phosphorylated 3 (human)
|
hSMAD2/iso:Long/Phos:3
|
"A smad2 isoform Long phosphorylated 3 in human. This form is phosphorylated on a [S/T] residue within the MH1-MH2 domain linker region, in addition to the two last Ser residues of the SSxS C-terminal motif. UniProtKB:Q15796-1, Ser-240/Ser-465/Ser-467, MOD:00046." [PMID:11027280]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000653 |
smad2 isoform Long phosphorylated 4
|
SMAD2/iso:Long/Phos:4
|
"A smad2 isoform Long phosphorylated form in which the phosphorylation occurs at the clusters of [S/T]P motifs within the MH1-MH2 domain linker region through the MAP kinase cascade in the oncogenic Ras-activated pathway. Example: UniProtKB:Q15796-1, Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255, MOD:00046." [PMID:10197981]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025937 |
smad2 isoform Long phosphorylated 4 (human)
|
hSMAD2/iso:Long/Phos:4
|
"A smad2 isoform Long phosphorylated 4 in human. This form is phosphorylated at the clusters of [S/T]P motifs within the MH1-MH2 domain linker region. UniProtKB:Q15796-1, Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255, MOD:00046." [PMID:10197981]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
modification
|
|
PR:000002570 |
smad2 isoform Long unmodified form
|
SMAD2/iso:Long/UnMod
|
"A smad2 isoform Long that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
|
|
Yes |
|
|
|
|
| | | | | | |
| | | | |
modification
|
|
PR:000026718 |
smad2 isoform Long, initiator methionine removed form
|
SMAD2/iso:Long/InitMet-
|
"A smad2 isoform Long that has had the initiator methionine removed." [PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | | |
sequence
|
|
PR:000000469 |
smad2 isoform Short
|
SMAD2/iso:Short
|
"A smad2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15796-2 or a 1:1 ortholog thereof." [PMID:8752209, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-sequence
|
|
PR:Q15796-2 |
mothers against decapentaplegic homolog 2 isoform Short (human)
|
hSMAD2/iso:Short
|
"A smad2 isoform Short that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15796]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000025938 |
smad2 isoform Short phosphorylated 1 (human)
|
hSMAD2/iso:Short/Phos:1
|
"A smad2 isoform Short phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046." [PRO:CNA]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000036556 |
smad2 isoform Short acetylated and phosphorylated 1 (human)
|
hSMAD2/iso:Short/AcPhos:1
|
"A smad2 isoform Short acetylated and phosphorylated 1 in human. UniProtKB:Q15796-2, Lys-19, MOD:00064|Ser-435/Ser-437, MOD:00046." [PMID:17074756, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000045494 |
smad2 isoform Short unphosphorylated 1 (human)
|
hSMAD2/iso:Short/UnPhos:1
|
"A mothers against decapentaplegic homolog 2 isoform Short (human) that lacks phosphorylation on the last two Ser of the C-terminal SSxS motif. UniProtKB:Q15796-2, Ser-435/Ser-437, PR:000026291." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-sequence
|
|
PR:Q62432-2 |
mothers against decapentaplegic homolog 2 isoform Short (mouse)
|
mSMAD2/iso:Short
|
"A smad2 isoform Short that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q62432]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000025943 |
smad2 isoform Short phosphorylated 1 (mouse)
|
mSMAD2/iso:Short/Phos:1
|
"A smad2 isoform Short phosphorylated 1 in mouse. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q62432-2, Ser-435/Ser-437, MOD:00046." [PRO:CNA]
|
Yes |
Yes |
|
|
|
|
| | | | | | |
| | | | |
modification
|
|
PR:000000575 |
smad2 isoform Short acetylated and phosphorylated form
|
SMAD2/iso:Short/AcPhos+
|
"A smad2 isoform Short that includes at least one acetylated residue and at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
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modification
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PR:000000655 |
smad2 isoform Short acetylated and phosphorylated 1
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SMAD2/iso:Short/AcPhos:1
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"A smad2 isoform Short acetylated and phosphorylated form in which the phosphorylation occurs at the last two Ser residues within the SSxS C-terminal motif by TGF-beta pathway activation and acetylated in a Lys residue within the MH1 domain by coactivators, such as CBP, PCAF and EP300. Example: UniProtKB:Q15796-2, Lys-19, MOD:00064|Ser-435/Ser-437, MOD:00046." [PMID:17074756]
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organism-modification
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PR:000036556 |
smad2 isoform Short acetylated and phosphorylated 1 (human)
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hSMAD2/iso:Short/AcPhos:1
|
"A smad2 isoform Short acetylated and phosphorylated 1 in human. UniProtKB:Q15796-2, Lys-19, MOD:00064|Ser-435/Ser-437, MOD:00046." [PMID:17074756, PRO:CNA]
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Yes |
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modification
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PR:000000576 |
smad2 isoform Short phosphorylated form
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SMAD2/iso:Short/PhosRes+
|
"A smad2 isoform Short that includes at least one phosphorylated residue." [PRO:CNA]
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modification
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PR:000000575 |
smad2 isoform Short acetylated and phosphorylated form
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SMAD2/iso:Short/AcPhos+
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"A smad2 isoform Short that includes at least one acetylated residue and at least one phosphorylated residue." [PRO:CNA]
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modification
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PR:000000655 |
smad2 isoform Short acetylated and phosphorylated 1
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SMAD2/iso:Short/AcPhos:1
|
"A smad2 isoform Short acetylated and phosphorylated form in which the phosphorylation occurs at the last two Ser residues within the SSxS C-terminal motif by TGF-beta pathway activation and acetylated in a Lys residue within the MH1 domain by coactivators, such as CBP, PCAF and EP300. Example: UniProtKB:Q15796-2, Lys-19, MOD:00064|Ser-435/Ser-437, MOD:00046." [PMID:17074756]
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organism-modification
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PR:000036556 |
smad2 isoform Short acetylated and phosphorylated 1 (human)
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hSMAD2/iso:Short/AcPhos:1
|
"A smad2 isoform Short acetylated and phosphorylated 1 in human. UniProtKB:Q15796-2, Lys-19, MOD:00064|Ser-435/Ser-437, MOD:00046." [PMID:17074756, PRO:CNA]
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Yes |
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modification
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PR:000000656 |
smad2 isoform Short phosphorylated 1
|
SMAD2/iso:Short/Phos:1
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"A smad2 isoform Short phosphorylated form in which the phosphorylation occurs at the last two Ser residues within the SSxS C-terminal motif by TGF-beta pathway activation. Example: UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046." [PMID:15630024, PMID:17074756, PMID:9873005]
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Yes |
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organism-modification
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PR:000025938 |
smad2 isoform Short phosphorylated 1 (human)
|
hSMAD2/iso:Short/Phos:1
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"A smad2 isoform Short phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046." [PRO:CNA]
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Yes |
Yes |
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organism-modification
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PR:000025943 |
smad2 isoform Short phosphorylated 1 (mouse)
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mSMAD2/iso:Short/Phos:1
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"A smad2 isoform Short phosphorylated 1 in mouse. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q62432-2, Ser-435/Ser-437, MOD:00046." [PRO:CNA]
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Yes |
Yes |
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modification
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PR:000002571 |
smad2 isoform Short unmodified form
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SMAD2/iso:Short/UnMod
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"A smad2 isoform Short that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
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modification
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PR:000018296 |
smad2, initiator methionine removed form
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SMAD2/InitMet-
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"A smad2 that has had the initiator methionine removed." [PRO:DNx]
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modification
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PR:000026718 |
smad2 isoform Long, initiator methionine removed form
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SMAD2/iso:Long/InitMet-
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"A smad2 isoform Long that has had the initiator methionine removed." [PRO:DNx]
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organism-modification
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PR:000049281 |
mothers against decapentaplegic homolog 2, initiator methionine removed form (human)
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hSMAD2/InitMet-
|
"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed. UniProtKB:Q15796, 2-467." [PRO:DNx, Reactome:R-HSA-3006352, Reactome:R-HSA-3006353]
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organism-modification
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PR:000049282 |
mothers against decapentaplegic homolog 2, initiator methionine removed phosphorylated 1 (human)
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hSMAD2/InitMet-/Phos:1
|
"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 465 and 467 of the amino acid sequence represented by UniProtKB:Q15796. UniProtKB:Q15796, 2-467, Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3009185, Reactome:R-HSA-3009186]
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organism-modification
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PR:000049283 |
mothers against decapentaplegic homolog 2, initiator methionine removed phosphorylated 5 (human)
|
hSMAD2/InitMet-/Phos:5
|
"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 220, and phosphoserine at positions 465 and 467 of the amino acid sequence represented by UniProtKB:Q15796. UniProtKB:Q15796, 2-467, Thr-220, MOD:00047|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3009189]
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organism-modification
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PR:000049284 |
mothers against decapentaplegic homolog 2, initiator methionine removed ubiquitinated form (human)
|
hSMAD2/InitMet-/UbiqLys+
|
"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed and that includes at least one ubiquitinated lysine. UniProtKB:Q15796, 2-467, MOD:01148." [PRO:DNx, Reactome:R-HSA-6782774]
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organism-modification
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PR:000064775 |
mothers against decapentaplegic homolog 2, initiator methionine removed phosphorylated and ubiquitinated 1 (human)
|
hSMAD2/InitMet-/PhosUbiq:1
|
"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed, that has been phosphorylated on the residues at the positions equivalent to Thr-220, Ser-465, and Ser-467 of the amino acid sequence represented by UniProtKB:Q15796-1, and that includes at least one ubiquitinated lysine. Example: UniProtKB:Q15796-1, 2-467, Thr-220, MOD:00047|Ser-465/Ser-467, MOD:00046|MOD:01148." [PRO:DNx, Reactome:R-HSA-9773843]
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organism-modification
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PR:000060357 |
mothers against decapentaplegic homolog 2 sequence variant D300A, initiator methionine removed phosphorylated 1 (human)
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hSMAD2/var:D300A/InitMet-/Phos:1
|
"A mothers against decapentaplegic homolog 2 (human) that has an Ala residue at the position equivalent to Asp-300 of the amino acid sequence represented by UniProtKB:Q15796-1, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-465 and Ser-467. Example: UniProtKB:Q15796-1, 2-467, Asp-300, CHEBI:46217|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315064]
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organism-modification
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PR:000060522 |
mothers against decapentaplegic homolog 2 sequence variant S464L, initiator methionine removed form (human)
|
hSMAD2/var:S464L/InitMet-
|
"A mothers against decapentaplegic homolog 2 (human) that has a Leu residue at the position equivalent to Ser-464 of the amino acid sequence represented by UniProtKB:Q15796-1 and that has had the initiator methionine removed. Example: UniProtKB:Q15796-1, 2-467, Ser-464, CHEBI:30006." [PRO:DNx, Reactome:R-HSA-3304383]
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organism-modification
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PR:000060657 |
mothers against decapentaplegic homolog 2 sequence variant D300V, initiator methionine removed phosphorylated 1 (human)
|
hSMAD2/var:D300V/InitMet-/Phos:1
|
"A mothers against decapentaplegic homolog 2 (human) that has a Val residue at the position equivalent to Asp-300 of the amino acid sequence represented by UniProtKB:Q15796-1, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-465 and Ser-467. Example: UniProtKB:Q15796-1, 2-467, Asp-300, CHEBI:30015|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315067]
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organism-modification
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PR:000060862 |
mothers against decapentaplegic homolog 2 sequence variant D300N, initiator methionine removed phosphorylated 1 (human)
|
hSMAD2/var:D300N/InitMet-/Phos:1
|
"A mothers against decapentaplegic homolog 2 (human) that has an Asn residue at the position equivalent to Asp-300 of the amino acid sequence represented by UniProtKB:Q15796-1, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-465 and Ser-467. Example: UniProtKB:Q15796-1, 2-467, Asp-300, CHEBI:50347|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315066]
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organism-modification
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PR:000061944 |
mothers against decapentaplegic homolog 2 sequence variant A354T, initiator methionine removed phosphorylated 1 (human)
|
hSMAD2/var:A354T/InitMet-/Phos:1
|
"A mothers against decapentaplegic homolog 2 (human) that has a Thr residue at the position equivalent to Ala-354 of the amino acid sequence represented by UniProtKB:Q15796-1, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-465 and Ser-467. Example: UniProtKB:Q15796-1, 2-467, Ala-354, CHEBI:30013|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315474]
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organism-modification
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|
PR:000062120 |
mothers against decapentaplegic homolog 2 sequence variant P305Q, initiator methionine removed phosphorylated 1 (human)
|
hSMAD2/var:P305Q/InitMet-/Phos:1
|
"A mothers against decapentaplegic homolog 2 (human) that has a Gln residue at the position equivalent to Pro-305 of the amino acid sequence represented by UniProtKB:Q15796-1, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-465 and Ser-467. Example: UniProtKB:Q15796-1, 2-467, Pro-305, CHEBI:30011|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315070]
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organism-modification
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|
PR:000062419 |
mothers against decapentaplegic homolog 2, initiator methionine removed phosphorylated 2 (human)
|
hSMAD2/InitMet-/Phos:2
|
"A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-250 of the amino acid sequence represented by UniProtKB:Q15796-1. Example: UniProtKB:Q15796-1, 2-467, Ser-250, MOD:00046." [PRO:DNx, Reactome:R-HSA-9731121]
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organism-modification
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|
PR:000063661 |
mothers against decapentaplegic homolog 2 sequence variant S464*, initiator methionine removed form (human)
|
hSMAD2/var:S464*/InitMet-
|
"A mothers against decapentaplegic homolog 2 (human) that has has been truncated after the position equivalent to Cys-463 of the amino acid sequence represented by UniProtKB:Q15796-1 and that has had the initiator methionine removed. Example: UniProtKB:Q15796-1, 2-463." [PRO:DNx, Reactome:R-HSA-3304362]
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organism-modification
|
|
PR:000063912 |
mothers against decapentaplegic homolog 2 sequence variant S467P, initiator methionine removed form (human)
|
hSMAD2/var:S467P/InitMet-
|
"A mothers against decapentaplegic homolog 2 (human) that has a Pro residue at the position equivalent to Ser-467 of the amino acid sequence represented by UniProtKB:Q15796-1 and that has had the initiator methionine removed. Example: UniProtKB:Q15796-1, 2-467, Ser-467, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-3304375]
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organism-modification
|
|
PR:000064349 |
mothers against decapentaplegic homolog 2 sequence variant P305L, initiator methionine removed phosphorylated 1 (human)
|
hSMAD2/var:P305L/InitMet-/Phos:1
|
"A mothers against decapentaplegic homolog 2 (human) that has a Leu residue at the position equivalent to Pro-305 of the amino acid sequence represented by UniProtKB:Q15796-1, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-465 and Ser-467. Example: UniProtKB:Q15796-1, 2-467, Pro-305, CHEBI:30006|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315471]
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modification
|
|
PR:000028327 |
smad2 unmodified form
|
SMAD2/UnMod
|
"A smad2 that lacks any modified amino-acid residues." [PRO:DAN]
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modification
|
|
PR:000002570 |
smad2 isoform Long unmodified form
|
SMAD2/iso:Long/UnMod
|
"A smad2 isoform Long that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
|
|
Yes |
|
|
|
|
| | | | | | |
| | | | |
modification
|
|
PR:000002571 |
smad2 isoform Short unmodified form
|
SMAD2/iso:Short/UnMod
|
"A smad2 isoform Short that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
|
|
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|
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| | | | |
modification
|
|
PR:000025973 |
smad2 isoform unmodified form
|
SMAD2/iso:[Long/Short]/UnMod
|
"A smad2 unmodified form that corresponds to either isoform Long or isoform Short." [PMID:19135894, PRO:CNA, PRO:DAN]
|
|
Yes |
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000002570 |
smad2 isoform Long unmodified form
|
SMAD2/iso:Long/UnMod
|
"A smad2 isoform Long that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
|
|
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|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000002571 |
smad2 isoform Short unmodified form
|
SMAD2/iso:Short/UnMod
|
"A smad2 isoform Short that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
|
|
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|
|
|
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| | | | | | |
modification
|
|
PR:000050146 |
smad2 phosphorylated 1
|
SMAD2/Phos:1
|
"A smad2 that has been phosphorylated on the last two Ser residues within the SSxS C-terminal motif by TGF-beta pathway activation. Example: UniProtKB:Q15796, Ser-465/Ser-467, MOD:00046." [PRO:DAN]
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|
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organism-modification
|
|
PR:000050145 |
smad2 phosphorylated 1 (human)
|
hSMAD2/Phos:1
|
"A smad2 phosphorylated 1 in human. This form is phosphorylated in the last two Ser of the C-terminal SSxS motif. UniProtKB:Q15796, Ser-465/Ser-467, MOD:00046." [PMID:8980228, PMID:9346966]
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