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Protein Ontology report - ribosomal protein S6 kinase beta-1 isoform 2
PR:000000311 - http://purl.obolibrary.org/obo/PR_000000311
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000311   
  PRO nameribosomal protein S6 kinase beta-1 isoform 2 
  Synonyms
PRO-Short-label: EXACT:RPS6KB1/iso:2
Other: RELATED:Alpha II
  Definition"A ribosomal protein S6 kinase beta-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23443-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000123 ribosomal protein S6 kinase beta-1
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification2                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000311
ribosomal protein S6 kinase beta-1 isoform 2
RPS6KB1/iso:2
"A ribosomal protein S6 kinase beta-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23443-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]

organism-sequence


PR:P23443-2
ribosomal protein S6 kinase beta-1 isoform Alpha II (human)
hRPS6KB1/iso:Alpha II
"A ribosomal protein S6 kinase beta-1 isoform 2 that is encoded in the genome of human." [PRO:CNA]
Yes
organism-modification


PR:000036481
ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1 (human)
hRPS6KB1/iso:2/Phos:1
"A ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1 in human." [PMID:1922062, PRO:CNA]
Yes
organism-sequence


PR:Q8BSK8-2
ribosomal protein S6 kinase beta-1 isoform Alpha II (mouse)
mRPS6KB1/iso:Alpha II
"A ribosomal protein S6 kinase beta-1 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]

modification


PR:000000464
ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated form
RPS6KB1/iso:2/PhosRes+
"A ribosomal protein S6 kinase beta-1 isoform 2 that includes at least one phosphorylated residue." [PRO:CNA]

modification


PR:000000568
ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1
RPS6KB1/iso:2/Phos:1
"A ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated form in which the phosphorylation occurs within the AGC-kinase C-terminal domain. These sites serve as phosphorylation-regulated switches to control both intra- and inter-molecular interactions. Without these priming phosphorylations, the kinases are catalytically inactive." [PMID:1922062]

organism-modification


PR:000036481
ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1 (human)
hRPS6KB1/iso:2/Phos:1
"A ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1 in human." [PMID:1922062, PRO:CNA]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036481 hRPS6KB1/iso:2/Phos:1 acts_upstream_of_or_withinGO:0007165 signal transduction PMID:1922062
enablesGO:0004672 protein kinase activity PMID:1922062
PR:P23443-2 hRPS6KB1/iso:Alpha II acts_upstream_of_or_withinGO:0007165 signal transduction PMID:1922062
enablesNOT GO:0004672 protein kinase activity PMID:1922062