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Protein Ontology report - pituitary homeobox 2 isoform Ptx2A
PR:000000294 -
http://purl.obolibrary.org/obo/PR_000000294
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000294
PRO name
pituitary homeobox 2 isoform Ptx2A
Synonyms
PRO-Short-label
:
EXACT:
PITX2/iso:Ptx2A
Other
:
EXACT:
ARP1A | pituitary homeobox 2 isoform 1 | Pitx2a
Definition
"A pituitary homeobox 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:Q99697-3
or a 1:1 ortholog thereof." [
PMID:10585561
, PRO:CNA, PRO:DAN]
PRO Category
sequence
Parent
PR:000000117
pituitary homeobox 2
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
4
Modification
0
Organism-Modification
0
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000000294
pituitary homeobox 2 isoform Ptx2A
PITX2/iso:Ptx2A
"A pituitary homeobox 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99697-3 or a 1:1 ortholog thereof." [PMID:10585561, PRO:CNA, PRO:DAN]
organism-sequence
PR:O93385-2
pituitary homeobox 2 isoform Ptx2A (chicken)
chick-PITX2/iso:Ptx2A
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of chicken." [PRO:DNx, UniProtKB:O93385]
organism-sequence
PR:P97474-3
pituitary homeobox 2 isoform Ptx2A (mouse)
mPITX2/iso:Ptx2A
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P97474]
Yes
organism-sequence
PR:Q99697-3
pituitary homeobox 2 isoform Ptx2A (human)
hPITX2/iso:Ptx2A
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99697]
Yes
organism-sequence
PR:Q9R0W1-2
pituitary homeobox 2 isoform Ptx2A (rat)
rPITX2/iso:Ptx2A
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of rat." [PRO:DNx, UniProtKB:Q9R0W1]
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Functional Annotation (GO-centric view)
Switch to
PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007266
Rho protein signal transduction
PR:P97474-3
mPITX2/iso:Ptx2A
PMID:11854422
NOT
GO:0007368
determination of left/right symmetry
PR:P97474-3
mPITX2/iso:Ptx2A
PMID:10585561
GO:0030036
actin cytoskeleton organization
PR:P97474-3
mPITX2/iso:Ptx2A
PMID:11854422
GO:0043388
positive regulation of DNA binding
PR:P97474-3
mPITX2/iso:Ptx2A
MGI_ref:3796777;
PMID:18458156
Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
PR:P97474-3
mPITX2/iso:Ptx2A
MGI_ref:3796777;
PMID:18458156
GO:0003677
DNA binding
PR:P97474-3
mPITX2/iso:Ptx2A
MGI_ref:3796777;
PMID:18458156
GO:0003712
transcription coregulator activity
PR:P97474-3
mPITX2/iso:Ptx2A
MGI_ref:3796777;
PMID:18458156
GO:0005515
protein binding
PR:P97474-3
mPITX2/iso:Ptx2A
MGI_ref:3796777;
PMID:18458156
PR:Q99697-3
hPITX2/iso:Ptx2A
PMID:11948188
GO:0008134
transcription factor binding
PR:P97474-3
mPITX2/iso:Ptx2A
PMID:15385555
PR:Q99697-3
hPITX2/iso:Ptx2A
PMID:16449236
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634
nucleus
PR:P97474-3
mPITX2/iso:Ptx2A
PMID:11854422
PR:P97474-3
mPITX2/iso:Ptx2A
PMID:11854422
PR:P97474-3
mPITX2/iso:Ptx2A
PMID:11854422
PR:P97474-3
mPITX2/iso:Ptx2A
PMID:11854422
PR:Q99697-3
hPITX2/iso:Ptx2A
PMID:16449236
