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Protein Ontology report - activin/inhibin beta C chain
PR:000000218 - http://purl.obolibrary.org/obo/PR_000000218
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000218   
  PRO nameactivin/inhibin beta C chain 
  Synonyms
PRO-Short-label: EXACT:INHBC
Other: EXACT:activin beta-C chain
  Definition"An activin/inhibin beta subunit that is a translation product of the human INHBC gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000072 activin/inhibin beta subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000218 activin/inhibin beta C chain
INHBC

organism-gene


PR:P55103 inhibin beta C chain (human)
hINHBC

organism-sequence


PR:P55103-1 inhibin beta C chain isoform 1 (human)
hINHBC/iso:1

organism-modification


PR:000036545 inhibin beta C chain isoform 1 mature form (human)
hINHBC/iso:1/mature
Yes
organism-gene


PR:P55104 inhibin beta C chain (mouse)
mINHBC

organism-sequence


PR:P55104-1 inhibin beta C chain isoform 1 (mouse)
mINHBC/iso:1

organism-gene


PR:Q9WUK5 inhibin beta C chain (rat)
rINHBC

sequence


PR:000000444 inhibin beta C chain isoform 1
INHBC/iso:1

organism-sequence


PR:P55103-1 inhibin beta C chain isoform 1 (human)
hINHBC/iso:1

organism-modification


PR:000036545 inhibin beta C chain isoform 1 mature form (human)
hINHBC/iso:1/mature
Yes
organism-sequence


PR:P55104-1 inhibin beta C chain isoform 1 (mouse)
mINHBC/iso:1

modification


PR:000021916 inhibin beta C chain isoform 1, signal peptide removed form
INHBC/iso:1/SigPep-

modification


PR:000000642 inhibin beta C chain isoform 1 mature form
INHBC/iso:1/mature

organism-modification


PR:000036545 inhibin beta C chain isoform 1 mature form (human)
hINHBC/iso:1/mature
Yes
modification


PR:000021933 activin/inhibin beta C chain proteolytic cleavage product
INHBC/ClvPrd

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0032926 negative regulation of activin receptor signaling pathwayPR:000036545 hINHBC/iso:1/mature PMID:12960042; PMID:16627954

Molecular Function GO Term
Protein Forms & Complexes
Evidence
contributes_to GO:0005160 transforming growth factor beta receptor bindingPR:000036545 hINHBC/iso:1/mature PMID:7826378
GO:0046983 protein dimerization activityPR:000036545 hINHBC/iso:1/mature PMID:11134153

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005576 extracellular regionPR:000036545 hINHBC/iso:1/mature PMID:16627954; PMID:7826378
GO:0032991 protein-containing complexPR:000036545 hINHBC/iso:1/mature PMID:11134153; PMID:12960042