back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - bone morphogenetic protein 6
PR:000000167 - http://purl.obolibrary.org/obo/PR_000000167
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000167   
  PRO namebone morphogenetic protein 6 
  Synonyms
PRO-Short-label: EXACT:BMP6
Gene-based: RELATED:VGR | Vgr1
Other: EXACT:BMP-6 | VG-1-R | VG-1-related protein | VGR-1
  Definition"A bone morphogenetic protein that is a translation product of the human BMP6 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000034 bone morphogenetic protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000167
bone morphogenetic protein 6
BMP6
"A bone morphogenetic protein that is a translation product of the human BMP6 gene or a 1:1 ortholog thereof." [PRO:CNA]

organism-gene


PR:P20722
bone morphogenetic protein 6 (mouse)
mBMP6
"A bone morphogenetic protein 6 that is encoded in the genome of mouse." [OMA:P20722, PRO:DNx]

organism-sequence


PR:P20722-1
bone morphogenetic protein 6 isoform 1 (mouse)
mBMP6/iso:1
"A bone morphogenetic protein 6 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
Yes
organism-modification


PR:000036515
bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (mouse)
mBMP6/iso:1/ClvNGlyco:1
"A bone morphogenetic protein 6 isoform 1, mature form in mouse that has been N-glycosylated at Asn-451 of the amino acid sequence represented by UniProtKB:P20722-1. UniProtKB:P20722-1, 372-510, Asn-451, MOD:00160." [PMID:14623234, PMID:8089189, PRO:CNA, PRO:DAN]
Yes
organism-gene


PR:P22004
bone morphogenetic protein 6 (human)
hBMP6
"A bone morphogenetic protein 6 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P22004]

organism-sequence


PR:P22004-1
bone morphogenetic protein 6 isoform 1 (human)
hBMP6/iso:1
"A bone morphogenetic protein 6 isoform 1 that is encoded in the genome of human." [PRO:CNA]
Yes
organism-modification


PR:000036514
bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human)
hBMP6/iso:1/ClvNGlyco:1
"A bone morphogenetic protein 6 isoform 1, mature form in human that has been N-glycosylated at Asn-454 of the amino acid sequence represented by UniProtKB:P22004-1. UniProtKB:P22004-1, 375-513, Asn-454, MOD:00160." [PMID:12702725, PMID:15969083, PMID:16527843, PMID:18070108, PRO:CNA, PRO:DAN]
Yes
organism-gene


PR:Q04906
bone morphogenetic protein 6 (rat)
rBMP6
"A bone morphogenetic protein 6 that is encoded in the genome of rat." [OMA:Q04906, PRO:DNx]

sequence


PR:000000388
bone morphogenetic protein 6 isoform 1
BMP6/iso:1
"A bone morphogenetic protein 6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22004-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]

organism-sequence


PR:P20722-1
bone morphogenetic protein 6 isoform 1 (mouse)
mBMP6/iso:1
"A bone morphogenetic protein 6 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
Yes
organism-modification


PR:000036515
bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (mouse)
mBMP6/iso:1/ClvNGlyco:1
"A bone morphogenetic protein 6 isoform 1, mature form in mouse that has been N-glycosylated at Asn-451 of the amino acid sequence represented by UniProtKB:P20722-1. UniProtKB:P20722-1, 372-510, Asn-451, MOD:00160." [PMID:14623234, PMID:8089189, PRO:CNA, PRO:DAN]
Yes
organism-sequence


PR:P22004-1
bone morphogenetic protein 6 isoform 1 (human)
hBMP6/iso:1
"A bone morphogenetic protein 6 isoform 1 that is encoded in the genome of human." [PRO:CNA]
Yes
organism-modification


PR:000036514
bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human)
hBMP6/iso:1/ClvNGlyco:1
"A bone morphogenetic protein 6 isoform 1, mature form in human that has been N-glycosylated at Asn-454 of the amino acid sequence represented by UniProtKB:P22004-1. UniProtKB:P22004-1, 375-513, Asn-454, MOD:00160." [PMID:12702725, PMID:15969083, PMID:16527843, PMID:18070108, PRO:CNA, PRO:DAN]
Yes
modification


PR:000000611
bone morphogenetic protein 6 isoform 1, mature form
BMP6/iso:1/mature
"A bone morphogenetic protein 6 isoform 1 that has had the signal peptide and propeptide removed." [PMID:15969083]

organism-modification


PR:000036514
bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human)
hBMP6/iso:1/ClvNGlyco:1
"A bone morphogenetic protein 6 isoform 1, mature form in human that has been N-glycosylated at Asn-454 of the amino acid sequence represented by UniProtKB:P22004-1. UniProtKB:P22004-1, 375-513, Asn-454, MOD:00160." [PMID:12702725, PMID:15969083, PMID:16527843, PMID:18070108, PRO:CNA, PRO:DAN]
Yes
organism-modification


PR:000036515
bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (mouse)
mBMP6/iso:1/ClvNGlyco:1
"A bone morphogenetic protein 6 isoform 1, mature form in mouse that has been N-glycosylated at Asn-451 of the amino acid sequence represented by UniProtKB:P20722-1. UniProtKB:P20722-1, 372-510, Asn-451, MOD:00160." [PMID:14623234, PMID:8089189, PRO:CNA, PRO:DAN]
Yes
modification


PR:000021901
bone morphogenetic protein 6 isoform 1, signal peptide removed form
BMP6/iso:1/SigPep-
"A bone morphogenetic protein 6 isoform 1 that has had the signal peptide removed." [PRO:DNx]

modification


PR:000000611
bone morphogenetic protein 6 isoform 1, mature form
BMP6/iso:1/mature
"A bone morphogenetic protein 6 isoform 1 that has had the signal peptide and propeptide removed." [PMID:15969083]

organism-modification


PR:000036514
bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human)
hBMP6/iso:1/ClvNGlyco:1
"A bone morphogenetic protein 6 isoform 1, mature form in human that has been N-glycosylated at Asn-454 of the amino acid sequence represented by UniProtKB:P22004-1. UniProtKB:P22004-1, 375-513, Asn-454, MOD:00160." [PMID:12702725, PMID:15969083, PMID:16527843, PMID:18070108, PRO:CNA, PRO:DAN]
Yes
organism-modification


PR:000036515
bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (mouse)
mBMP6/iso:1/ClvNGlyco:1
"A bone morphogenetic protein 6 isoform 1, mature form in mouse that has been N-glycosylated at Asn-451 of the amino acid sequence represented by UniProtKB:P20722-1. UniProtKB:P20722-1, 372-510, Asn-451, MOD:00160." [PMID:14623234, PMID:8089189, PRO:CNA, PRO:DAN]
Yes
modification


PR:000021932
bone morphogenetic protein 6 proteolytic cleavage product
BMP6/ClvPrd
"A bone morphogenetic protein 6 that has been processed by proteolytic cleavage." [PRO:DAN]

Back to top
Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0001501 skeletal system developmentPR:000036514 hBMP6/iso:1/ClvNGlyco:1 PMID:12702725
PR:000036515 mBMP6/iso:1/ClvNGlyco:1 PMID:8089189
PR:P20722-1 mBMP6/iso:1 PMID:8089189
PR:P22004-1 hBMP6/iso:1 PMID:12702725
GO:0001934 positive regulation of protein phosphorylationPR:000036514 hBMP6/iso:1/ClvNGlyco:1 PMID:16527843
GO:0030509 BMP signaling pathwayPR:000036514 hBMP6/iso:1/ClvNGlyco:1 PMID:15969083
PR:000036515 mBMP6/iso:1/ClvNGlyco:1 PMID:14623234
PR:P20722-1 mBMP6/iso:1 PMID:8089189
PR:P22004-1 hBMP6/iso:1 PMID:12702725
GO:0032349 positive regulation of aldosterone biosynthetic processPR:000036514 hBMP6/iso:1/ClvNGlyco:1 PMID:16527843

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0042803 protein homodimerization activityPR:000036514 hBMP6/iso:1/ClvNGlyco:1 PMID:15969083; PMID:18070108

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005615 extracellular spacePR:000036515 mBMP6/iso:1/ClvNGlyco:1 PMID:8089189