Protein Ontology

Home

Linked Open Data

Browse

Statistics

Download

RACE-PRO

PRO tracker

Community

PRO Consortium

Publications

Documentation

Protein Ontology report - interferon gamma isoform 1

PR:000000100 - http://purl.obolibrary.org/obo/PR_000000100

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000000100

PRO name

interferon gamma isoform 1

Synonyms

PRO-Short-label:

EXACT:

IFNG/iso:1

Definition

"An interferon gamma that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01579-1 or a 1:1 ortholog thereof." [PRO:CNA]

PRO Category

sequence

Parent

PR:000000017 interferon gamma

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Sequence	1	Organism-Sequence	2
Modification	3	Organism-Modification	4

Term Hierarchy
Visualization

DAG:

OLS:

Back to top

Protein Forms

Switch to Extended View

Category

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?

sequence

PR:000000100 interferon gamma isoform 1

IFNG/iso:1

organism-sequence

PR:P01579-1 interferon gamma isoform 1 (human)

hIFNG/iso:1

organism-modification

PR:000036419 interferon gamma isoform 1, signal peptide removed N-glycosylated 1 (human)

hIFNG/iso:1/SigPep-/NGlyco:1

Yes

organism-modification

PR:000036420 interferon gamma isoform 1 cleaved and N-glycosylated 2 (human)

hIFNG/iso:1/ClvNGlyco:2

Yes

organism-sequence

PR:P01580-1 interferon gamma isoform 1 (mouse)

mIFNG/iso:1

Yes

organism-modification

PR:000036418 interferon gamma isoform 1, signal peptide removed form (mouse)

mIFNG/iso:1/SigPep-

Yes

organism-modification

PR:000036407 interferon gamma isoform 1, signal peptide removed glycosylated form (mouse)

mIFNG/iso:1/SigPep-/GlycoRes+

Yes

modification

PR:000000445 interferon gamma isoform 1, signal peptide removed form

IFNG/iso:1/SigPep-

modification

PR:000000446 interferon gamma isoform 1, signal peptide removed glycosylated form

IFNG/iso:1/SigPep-/GlycoRes+

modification

PR:000000447 interferon gamma isoform 1 cleaved and N-glycosylated 2

IFNG/iso:1/ClvNGlyco:2

organism-modification

PR:000036420 interferon gamma isoform 1 cleaved and N-glycosylated 2 (human)

hIFNG/iso:1/ClvNGlyco:2

Yes

organism-modification

PR:000036407 interferon gamma isoform 1, signal peptide removed glycosylated form (mouse)

mIFNG/iso:1/SigPep-/GlycoRes+

Yes

organism-modification

PR:000036419 interferon gamma isoform 1, signal peptide removed N-glycosylated 1 (human)

hIFNG/iso:1/SigPep-/NGlyco:1

Yes

organism-modification

PR:000036418 interferon gamma isoform 1, signal peptide removed form (mouse)

mIFNG/iso:1/SigPep-

Yes

organism-modification

PR:000036407 interferon gamma isoform 1, signal peptide removed glycosylated form (mouse)

mIFNG/iso:1/SigPep-/GlycoRes+

Yes

Back to top

Functional Annotation (GO-centric view)

Switch to PRO Centric View

Biological Process GO Term	Protein Forms & Complexes	Evidence
GO:0032722 positive regulation of chemokine production	PR:P01580-1 mIFNG/iso:1	PMID:12925700
GO:0042742 defense response to bacterium	PR:P01580-1 mIFNG/iso:1	PMID:17661079
GO:0050776 regulation of immune response	PR:000036407 mIFNG/iso:1/SigPep-/GlycoRes+	PMID:12882831
GO:0050776 regulation of immune response	PR:000036418 mIFNG/iso:1/SigPep-	PMID:11441112
Molecular Function GO Term	Protein Forms & Complexes	Evidence
GO:0005125 cytokine activity	PR:000036407 mIFNG/iso:1/SigPep-/GlycoRes+	PMID:11027433; PMID:12925700; PMID:15240719
GO:0005125 cytokine activity	PR:000036418 mIFNG/iso:1/SigPep-	PMID:11441112
GO:0005133 type II interferon receptor binding	PR:000036419 hIFNG/iso:1/SigPep-/NGlyco:1	PMID:10986460
GO:0042803 protein homodimerization activity	PR:000036419 hIFNG/iso:1/SigPep-/NGlyco:1	PMID:3109913
GO:0042803 protein homodimerization activity	PR:000036420 hIFNG/iso:1/ClvNGlyco:2	PMID:1902591
Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005615 extracellular space	PR:000036407 mIFNG/iso:1/SigPep-/GlycoRes+	PMID:11057672; PMID:11728336; PMID:15240714
GO:0005615 extracellular space	PR:000036419 hIFNG/iso:1/SigPep-/NGlyco:1	PMID:6427223