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Protein Ontology report - decorin
PR:000000094 - http://purl.obolibrary.org/obo/PR_000000094
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000094   
  PRO namedecorin 
  Synonyms
PRO-Short-label: EXACT:DCN
Gene-based: RELATED:SLRR1B
Other: EXACT:bone proteoglycan II | PG-S2 | PG40
  Definition"A class 1 small leucine-rich proteoglycan that is a translation product of the human DCN gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000011 class 1 small leucine-rich proteoglycan
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence5                                                  Organism-Sequence 5                                        
         Modification6                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000000094

decorin

DCN


"A class 1 small leucine-rich proteoglycan that is a translation product of the human DCN gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P07585

decorin (human)

hDCN


"A decorin that is encoded in the genome of human." [PRO:CNA, UniProtKB:P07585]


organism-sequence



PR:P07585-1

decorin isoform A (human)

hDCN/iso:A


"A decorin isoform A that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036456

decorin isoform A, mature form (human)

hDCN/iso:A/mature


"A decorin isoform A, mature form in human. UniProtKB:P07585-1, 31-359." [PMID:17651433, PMID:9988678, PRO:CNA]

Yes

organism-modification



PR:000036457

decorin isoform A cleaved and glycosylated 1 (human)

hDCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated 1 in human. UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PMID:17651433, PMID:9988678, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036460

decorin isoform A cleaved 2 (human)

hDCN/iso:A/Clv:2


"A decorin isoform A cleaved 2 in human. UniProtKB:P07585-1, 31-170." [PMID:12621051, PMID:20947661, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:P07585-2

decorin isoform B (human)

hDCN/iso:B


"A decorin isoform B that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07585]


organism-sequence



PR:P07585-3

decorin isoform C (human)

hDCN/iso:C


"A decorin isoform C that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07585]


organism-sequence



PR:P07585-4

decorin isoform D (human)

hDCN/iso:D


"A decorin isoform D that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07585]


organism-sequence



PR:P07585-5

decorin isoform E (human)

hDCN/iso:E


"A decorin isoform E that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07585]


organism-modification



PR:000070796

decorin, mature xylosylserine form (human)

hDCN/mature/XylSer+


"A decorin (human) that has had the signal peptide and propeptide removed, and that includes at least one xylosylserine. Example: UniProtKB:P07585-1, 31-359, MOD:00814." [PRO:DNx, Reactome:R-HSA-2064097]


organism-modification



PR:000036457

decorin isoform A cleaved and glycosylated 1 (human)

hDCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated 1 in human. UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PMID:17651433, PMID:9988678, PRO:CNA, PRO:DAN]

Yes

organism-gene



PR:P28654

decorin (mouse)

mDCN


"A decorin that is encoded in the genome of mouse." [OMA:P28654, PRO:DNx]


organism-gene



PR:P28675

decorin (chicken)

chick-DCN


"A decorin that is encoded in the genome of chicken." [OMA:P28675, PRO:DNx]


organism-gene



PR:Q01129

decorin (rat)

rDCN


"A decorin that is encoded in the genome of rat." [OMA:Q01129, PRO:DNx]


sequence



PR:000000271

decorin isoform A

DCN/iso:A


"A decorin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07585-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P07585-1

decorin isoform A (human)

hDCN/iso:A


"A decorin isoform A that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036456

decorin isoform A, mature form (human)

hDCN/iso:A/mature


"A decorin isoform A, mature form in human. UniProtKB:P07585-1, 31-359." [PMID:17651433, PMID:9988678, PRO:CNA]

Yes

organism-modification



PR:000036457

decorin isoform A cleaved and glycosylated 1 (human)

hDCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated 1 in human. UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PMID:17651433, PMID:9988678, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036460

decorin isoform A cleaved 2 (human)

hDCN/iso:A/Clv:2


"A decorin isoform A cleaved 2 in human. UniProtKB:P07585-1, 31-170." [PMID:12621051, PMID:20947661, PRO:CNA, PRO:DAN]

Yes

modification



PR:000000550

decorin isoform A cleaved 2

DCN/iso:A/Clv:2


"A decorin isoform A that has been cleaved after the Phe residue within the F[NS]GLN motif as a result of the catabolic processing of decorin. This form lacks most of the leucine-rich domains and is abundant in adult skin tissue." [PMID:12621051]


organism-modification



PR:000036460

decorin isoform A cleaved 2 (human)

hDCN/iso:A/Clv:2


"A decorin isoform A cleaved 2 in human. UniProtKB:P07585-1, 31-170." [PMID:12621051, PMID:20947661, PRO:CNA, PRO:DAN]

Yes

modification



PR:000021897

decorin isoform A, signal peptide removed form

DCN/iso:A/SigPep-


"A decorin isoform A that has had the signal peptide removed." [PRO:DNx]


modification



PR:000000429

decorin isoform A cleaved and glycosylated form

DCN/iso:A/ClvGlyco+


"A decorin isoform A, signal peptide removed form that has had the propeptide removed and that includes at least one glycosylated residue." [PRO:CNA, PRO:DAN]


modification



PR:000000545

decorin isoform A cleaved and glycosylated 1

DCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated form that has been modified with O-linked glycosaminoglycan at the most N-terminal SG site and additional N-linked glycosylated Asn residues. Example: UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PRO:CNA, PRO:DAN]


organism-modification



PR:000036457

decorin isoform A cleaved and glycosylated 1 (human)

hDCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated 1 in human. UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PMID:17651433, PMID:9988678, PRO:CNA, PRO:DAN]

Yes

modification



PR:000000544

decorin isoform A, mature form

DCN/iso:A/mature


"A decorin isoform A, signal peptide removed form that has been processed by subsequent removal of the propeptide, rendering the mature decorin protein core." [PRO:CNA]


modification



PR:000000429

decorin isoform A cleaved and glycosylated form

DCN/iso:A/ClvGlyco+


"A decorin isoform A, signal peptide removed form that has had the propeptide removed and that includes at least one glycosylated residue." [PRO:CNA, PRO:DAN]


modification



PR:000000545

decorin isoform A cleaved and glycosylated 1

DCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated form that has been modified with O-linked glycosaminoglycan at the most N-terminal SG site and additional N-linked glycosylated Asn residues. Example: UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PRO:CNA, PRO:DAN]


organism-modification



PR:000036457

decorin isoform A cleaved and glycosylated 1 (human)

hDCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated 1 in human. UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PMID:17651433, PMID:9988678, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036456

decorin isoform A, mature form (human)

hDCN/iso:A/mature


"A decorin isoform A, mature form in human. UniProtKB:P07585-1, 31-359." [PMID:17651433, PMID:9988678, PRO:CNA]

Yes

organism-modification



PR:000036457

decorin isoform A cleaved and glycosylated 1 (human)

hDCN/iso:A/ClvGlyco:1


"A decorin isoform A cleaved and glycosylated 1 in human. UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PMID:17651433, PMID:9988678, PRO:CNA, PRO:DAN]

Yes

sequence



PR:000000272

decorin isoform B

DCN/iso:B


"A decorin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07585-2 or a 1:1 ortholog thereof." [NCBIGene:1634, PRO:CNA, PRO:DAN]


organism-sequence



PR:P07585-2

decorin isoform B (human)

hDCN/iso:B


"A decorin isoform B that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07585]


sequence



PR:000000273

decorin isoform C

DCN/iso:C


"A decorin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07585-3 or a 1:1 ortholog thereof." [NCBIGene:1634, PRO:CNA, PRO:DAN]


organism-sequence



PR:P07585-3

decorin isoform C (human)

hDCN/iso:C


"A decorin isoform C that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07585]


sequence



PR:000000274

decorin isoform D

DCN/iso:D


"A decorin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07585-4 or a 1:1 ortholog thereof." [NCBIGene:1634, PRO:CNA, PRO:DAN]


organism-sequence



PR:P07585-4

decorin isoform D (human)

hDCN/iso:D


"A decorin isoform D that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07585]


sequence



PR:000000275

decorin isoform E

DCN/iso:E


"A decorin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07585-5 or a 1:1 ortholog thereof." [NCBIGene:1634, PRO:CNA, PRO:DAN]


organism-sequence



PR:P07585-5

decorin isoform E (human)

hDCN/iso:E


"A decorin isoform E that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07585]


modification



PR:000018276

decorin proteolytic cleavage product

DCN/ClvPrd


"A decorin that has been processed by proteolytic cleavage." [PRO:DNx]


modification



PR:000000550

decorin isoform A cleaved 2

DCN/iso:A/Clv:2


"A decorin isoform A that has been cleaved after the Phe residue within the F[NS]GLN motif as a result of the catabolic processing of decorin. This form lacks most of the leucine-rich domains and is abundant in adult skin tissue." [PMID:12621051]


organism-modification



PR:000036460

decorin isoform A cleaved 2 (human)

hDCN/iso:A/Clv:2


"A decorin isoform A cleaved 2 in human. UniProtKB:P07585-1, 31-170." [PMID:12621051, PMID:20947661, PRO:CNA, PRO:DAN]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036456 hDCN/iso:A/mature
UniProtKB:P07585-1, 31-359
acts_upstream_of_or_withinGO:0030199 collagen fibril organization PMID:17651433
enablesGO:0005154 epidermal growth factor receptor binding PMID:9988678
located_inGO:0031012 extracellular matrix PMID:17651433
PR:000036457 hDCN/iso:A/ClvGlyco:1
UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160
acts_upstream_of_or_withinGO:0030199 collagen fibril organization PMID:17651433
enablesGO:0005154 epidermal growth factor receptor binding PMID:9988678
located_inGO:0031012 extracellular matrix PMID:17651433; PMID:9988678
PR:000036460 hDCN/iso:A/Clv:2
UniProtKB:P07585-1, 31-170
located_inGO:0031012 extracellular matrix PMID:12621051
PR:P07585-1 hDCN/iso:A acts_upstream_of_or_withinGO:0030199 collagen fibril organization PMID:17651433
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PMID:11879191