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Protein Ontology report - TGF-beta receptor type-2 isoform RII-1
PR:000000048 - http://purl.obolibrary.org/obo/PR_000000048
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000048   
  PRO nameTGF-beta receptor type-2 isoform RII-1 
  Synonyms
PRO-Short-label: EXACT:TGFBR2/iso:RII-1
Other: EXACT:TGF-beta receptor isoform 1 | TGFBR2 isoform 1
  Definition"A TGF-beta receptor type-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62312-2 or a 1:1 ortholog thereof." [PMID:7957954, PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000005 TGF-beta receptor type-2
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification5                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?
sequence



PR:000000048 TGF-beta receptor type-2 isoform RII-1

TGFBR2/iso:RII-1


organism-sequence



PR:P37173-1 TGF-beta receptor type-2 isoform RII-1 (human)

hTGFBR2/iso:RII-1


organism-modification



PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human)

hTGFBR2/iso:RII-1/SigPep-

Yes

organism-modification



PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)

hTGFBR2/iso:RII-1/SigPep-/Phos:1


Yes
organism-sequence



PR:Q62312-2 TGF-beta receptor type-2 isoform RII-1 (mouse)

mTGFBR2/iso:RII-1

Yes

modification



PR:000000198 TGF-beta receptor type-2 isoform RII-1 phosphorylated form

TGFBR2/iso:RII-1/PhosRes+


modification



PR:000000410 TGF-beta receptor type-2 isoform RII-1 phosphorylated 1

TGFBR2/iso:RII-1/Phos:1


modification



PR:000003175 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated form

TGFBR2/iso:RII-1/SigPep-/PhosRes+


modification



PR:000003176 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1

TGFBR2/iso:RII-1/SigPep-/Phos:1


Yes
organism-modification



PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)

hTGFBR2/iso:RII-1/SigPep-/Phos:1


Yes
modification



PR:000000409 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form

TGFBR2/iso:RII-1/SigPep-


modification



PR:000003175 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated form

TGFBR2/iso:RII-1/SigPep-/PhosRes+


modification



PR:000003176 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1

TGFBR2/iso:RII-1/SigPep-/Phos:1


Yes
organism-modification



PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)

hTGFBR2/iso:RII-1/SigPep-/Phos:1


Yes
organism-modification



PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human)

hTGFBR2/iso:RII-1/SigPep-

Yes

organism-modification



PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)

hTGFBR2/iso:RII-1/SigPep-/Phos:1


Yes
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TGFBR2/iso:RII-1 forms found in complexes   

TGFBR2/iso:RII-1 Component
Complexes
PR:000003176 TGFBR2/iso:RII-1/SigPep-/Phos:1 PR:000025976 transforming growth factor beta type II receptor homodimeric complex phosphorylated form
PR:000025962 hTGFBR2/iso:RII-1/SigPep-/Phos:1 PR:000025963 transforming growth factor beta type II receptor homodimeric complex phosphorylated form (human)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0007179 transforming growth factor beta receptor signaling pathwayPR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:11483955
GO:0007181 transforming growth factor beta receptor complex assemblyPR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1310899; PMID:8774881

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0005026 transforming growth factor beta receptor activity, type IIPR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:11483955
GO:0005515 protein bindingPR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1850637
GO:0050431 transforming growth factor beta bindingPR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:11850637; PMID:1310899

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0016020 membranePR:000036408 hTGFBR2/iso:RII-1/SigPep- PMID:1310899
PR:Q62312-2 mTGFBR2/iso:RII-1 PMID:7957954