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gene
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PR:000000037 |
BMP receptor type-2
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BMPR2
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"A TGF-beta superfamily receptor type-2 with activin receptor domain that is a translation product of the human BMPR2 gene or a 1:1 ortholog thereof. Bone morphogenetic protein (BMP) signals are transmitted by type 2 and type 1 serine/threonine kinase receptors. Type 2 receptors phosphorylate and activate type 1 receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators." [PRO:CNA]
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Yes |
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organism-gene
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PR:O35607 |
bone morphogenetic protein receptor type-2 (mouse)
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mBMPR2
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"A BMP receptor type-2 that is encoded in the genome of mouse." [OMA:O35607, PRO:DNx]
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organism-sequence
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PR:O35607-1 |
bone morphogenetic protein receptor type-2 isoform 1 (mouse)
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mBMPR2/iso:1
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"A BMP receptor type-2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-gene
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PR:Q13873 |
bone morphogenetic protein receptor type-2 (human)
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hBMPR2
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"A BMP receptor type-2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q13873]
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organism-sequence
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PR:000000149 |
BMP receptor type-2 sequence variant C60Y (human)
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hBMPR2/var:C60Y
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"A bone morphogenetic protein receptor type-2 (human) that has a Tyr residue at the position equivalent to Cys-60 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-60, CHEBI:46858." [PMID:11015450, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000150 |
BMP receptor type-2 sequence variant D485G (human)
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hBMPR2/var:D485G
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"A bone morphogenetic protein receptor type-2 (human) that has a Gly residue at the position equivalent to Asp-485 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Asp-485, CHEBI:29947." [PMID:10973254, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000151 |
BMP receptor type-2 sequence variant R491Q (human)
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hBMPR2/var:R491Q
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"A bone morphogenetic protein receptor type-2 (human) that has a Gln residue at the position equivalent to Arg-491 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Arg-491, CHEBI:30011." [PMID:10903931, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000152 |
BMP receptor type-2 sequence variant R491W (human)
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hBMPR2/var:R491W
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"A bone morphogenetic protein receptor type-2 (human) that has a Trp residue at the position equivalent to Arg-491 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Arg-491, CHEBI:29954." [PMID:10903931, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000153 |
BMP receptor type-2 sequence variant K512T (human)
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hBMPR2/var:K512T
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"A bone morphogenetic protein receptor type-2 (human) that has a Thr residue at the position equivalent to Lys-512 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Lys-512, CHEBI:30013." [PMID:11115378, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000154 |
BMP receptor type-2 sequence variant N519K (human)
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hBMPR2/var:N519K
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"A bone morphogenetic protein receptor type-2 (human) that has a Lys residue at the position equivalent to Asn-519 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Asn-519, CHEBI:29967." [PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000155 |
BMP receptor type-2 sequence variant C117Y (human)
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hBMPR2/var:C117Y
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"A bone morphogenetic protein receptor type-2 (human) that has a Tyr residue at the position equivalent to Cys-117 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-117, CHEBI:46858." [PMID:11015450, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000156 |
BMP receptor type-2 sequence variant C118W (human)
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hBMPR2/var:C118W
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"A bone morphogenetic protein receptor type-2 (human) that has a Trp residue at the position equivalent to Cys-118 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-118, CHEBI:29954." [PMID:10973254, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000157 |
BMP receptor type-2 sequence variant C123R (human)
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hBMPR2/var:C123R
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"A bone morphogenetic protein receptor type-2 (human) that has an Arg residue at the position equivalent to Cys-123 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-123, CHEBI:29952." [PMID:11115378, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000158 |
BMP receptor type-2 sequence variant C123S (human)
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hBMPR2/var:C123S
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"A bone morphogenetic protein receptor type-2 (human) that has a Ser residue at the position equivalent to Cys-123 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-123, CHEBI:29999." [PMID:11115378, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000159 |
BMP receptor type-2 sequence variant E224D (human)
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hBMPR2/var:E224D
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"A bone morphogenetic protein receptor type-2 (human) that has an Asp residue at the position equivalent to Glu-224 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Glu-224, CHEBI:29958." [PMID:11115378, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000160 |
BMP receptor type-2 sequence variant C347Y (human)
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hBMPR2/var:C347Y
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"A bone morphogenetic protein receptor type-2 (human) that has a Tyr residue at the position equivalent to Cys-347 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-347, CHEBI:46858." [PMID:10973254, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000161 |
BMP receptor type-2 sequence variant C420R (human)
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hBMPR2/var:C420R
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"A bone morphogenetic protein receptor type-2 (human) that has an Arg residue at the position equivalent to Cys-420 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-420, CHEBI:29952." [PMID:11115378, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000162 |
BMP receptor type-2 sequence variant C483R (human)
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hBMPR2/var:C483R
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"A bone morphogenetic protein receptor type-2 (human) that has an Arg residue at the position equivalent to Cys-483 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-483, CHEBI:29952." [PMID:11015450, PMID:12358323, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:Q13873-1 |
bone morphogenetic protein receptor type-2 isoform 1 (human)
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hBMPR2/iso:1
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"A BMP receptor type-2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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organism-sequence
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PR:Q13873-2 |
bone morphogenetic protein receptor type-2 isoform h2 (human)
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hBMPR2/iso:h2
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"A bone morphogenetic protein receptor type-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13873-2." [PRO:DNx, UniProtKB:Q13873]
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organism-modification
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PR:000046497 |
bone morphogenetic protein receptor type-2, signal peptide removed form (human)
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hBMPR2/SigPep-
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"A bone morphogenetic protein receptor type-2 (human) that has had the signal peptide removed. UniProtKB:Q13873, 27-1038." [PRO:DNx, Reactome:R-HSA-201442]
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organism-modification
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PR:000057061 |
bone morphogenetic protein receptor type-2 N-glycosylated 1 (human)
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hBMPR2/NGlyco:1
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"A bone morphogenetic protein receptor type-2 (human) that has been N-glycosylated at the residue equivalent to Asn-827 of the amino acid sequence represented by UniProtKB:Q13873-1, in which the glycan composition is represented by GlyTouCan:G10486CT. Example: UniProtKB:Q13873-1, Asn-827, MOD:00160~GNO:G10486CT." [GlyGen:Q13873-1, PMID:29671580, PRO:DNx]
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organism-modification
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PR:000057062 |
bone morphogenetic protein receptor type-2 O-glycosylated 1 (human)
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hBMPR2/OGlyco:1
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"A bone morphogenetic protein receptor type-2 (human) that has been O-glycosylated at the residue equivalent to Thr-137 of the amino acid sequence represented by UniProtKB:Q13873-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q13873-1, Thr-137, MOD:00005~GNO:G43417UB." [GlyGen:Q13873-1, PMID:30459171, PRO:DNx]
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organism-modification
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PR:000065377 |
bone morphogenetic protein receptor type-2 methylated 1 (human)
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hBMPR2/Me:1
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"A bone morphogenetic protein receptor type-2 (human) that has been methylated on the residue at the position equivalent to Cys-910 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-910, MOD:00660." [IEDB_epitope:1035856, PRO:DNx]
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organism-modification
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PR:000065967 |
bone morphogenetic protein receptor type-2 deaminated 1 (human)
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hBMPR2/Deam:1
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"A bone morphogenetic protein receptor type-2 (human) that has been deaminated on the residue at the position equivalent to Asn-728 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Asn-728, MOD:00684." [IEDB_epitope:1583797, PRO:DNx]
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organism-modification
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PR:000073289 |
bone morphogenetic protein receptor type-2 deaminated 2 (human)
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hBMPR2/Deam:2
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"A bone morphogenetic protein receptor type-2 (human) that has been deaminated on the residue at the position equivalent to Asn-861 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Asn-861, MOD:00684." [IEDB_epitope:1738174, PRO:DNx]
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organism-modification
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PR:000081621 |
bone morphogenetic protein receptor type-2 deaminated 3 (human)
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hBMPR2/Deam:3
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"A bone morphogenetic protein receptor type-2 (human) that has been deaminated on the residue at the position equivalent to Asn-827 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Asn-827, MOD:00684." [IEDB_epitope:1591068, PRO:DNx]
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sequence
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PR:000000148 |
BMP receptor type-2 isoform 1
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BMPR2/iso:1
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"A BMP receptor type-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13873-1 or a 1:1 ortholog thereof." [PRO:CNA]
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organism-sequence
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PR:O35607-1 |
bone morphogenetic protein receptor type-2 isoform 1 (mouse)
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mBMPR2/iso:1
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"A BMP receptor type-2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-sequence
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PR:Q13873-1 |
bone morphogenetic protein receptor type-2 isoform 1 (human)
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hBMPR2/iso:1
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"A BMP receptor type-2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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