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 |
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| | |
| | | | | | | | |
family
|
|
PR:000000024 |
Rho-associated protein kinase
|
NOG
|
"A protein that is a translation product of an evolutionary-related gene with core domain composition consisting of an N-terminal Protein kinase domain (Pfam:PF00069), a Rho Binding domain (Pfam:PF08912), and a PH domain (Pfam:PF00169) and a Phorbol esters/diacylglycerol binding domain (C1 domain) (Pfam:PF00130) at the C-terminus. Rho-associated protein kinases are mediators of many cellular processes by being effectors of the small GTP-binding protein Rho." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | |
| | | | | | |
gene
|
|
PR:000000120 |
Rho-associated protein kinase 1
|
ROCK1
|
"A Rho-associated protein kinase that is a translation product of the human ROCK1 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:P70335 |
Rho-associated protein kinase 1 (mouse)
|
mROCK1
|
"A Rho-associated protein kinase 1 that is encoded in the genome of mouse." [OMA:P70335, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P70335-1 |
Rho-associated protein kinase 1 isoform 1 (mouse)
|
mROCK1/iso:1
|
"A Rho-associated protein kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036476 |
Rho-associated protein kinase 1 isoform 1 cleaved 1 (mouse)
|
mROCK1/iso:1/Clv:1
|
"A Rho-associated protein kinase 1 isoform 1 cleaved 1 in mouse. UniProtKB:P70335-1, 1-1113." [PMID:11283607, PMID:16983089, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P70335-2 |
Rho-associated protein kinase 1 isoform m2 (mouse)
|
mROCK1/iso:m2
|
"A Rho-associated protein kinase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70335-2." [PRO:DNx, UniProtKB:P70335]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:Q13464 |
Rho-associated protein kinase 1 (human)
|
hROCK1
|
"A Rho-associated protein kinase 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q13464]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q13464-1 |
Rho-associated protein kinase 1 isoform 1 (human)
|
hROCK1/iso:1
|
"A Rho-associated protein kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000026340 |
Rho-associated protein kinase 1 isoform 1 cleaved 1 (human)
|
hROCK1/iso:1/Clv:1
|
"A Rho-associated protein kinase 1 isoform 1 cleaved 1 in human. UniProtKB:Q13464-1, 1-1113." [PRO:DNx, UniProtKB:Q13464]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000044586 |
Rho-associated protein kinase 1 isoform 1 unmodified form (human)
|
hROCK1/iso:1/UnMod
|
"A Rho-associated protein kinase 1 isoform 1 unmodified form in human." [PRO:DNx]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000061208 |
Rho-associated protein kinase 1, initiator methionine removed form (human)
|
hROCK1/InitMet-
|
"A Rho-associated protein kinase 1 (human) that has had the initiator methionine removed. UniProtKB:Q13464, 2-1354." [PRO:DNx, Reactome:R-HSA-212509, Reactome:R-HSA-6804967, Reactome:R-HSA-6806527]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000070060 |
Rho-associated protein kinase 1 deaminated 1 (human)
|
hROCK1/Deam:1
|
"A Rho-associated protein kinase 1 (human) that has been deaminated on the residue at the position equivalent to Gln-787 of the amino acid sequence represented by UniProtKB:Q13464. UniProtKB:Q13464, Gln-787, MOD:00685." [IEDB_epitope:1987374, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000070524 |
Rho-associated protein kinase 1 phosphorylated 1 (human)
|
hROCK1/Phos:1
|
"A Rho-associated protein kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-1301 of the amino acid sequence represented by UniProtKB:Q13464. UniProtKB:Q13464, Ser-1301, MOD:00046." [IEDB_epitope:1360482, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000082399 |
Rho-associated protein kinase 1 deaminated 2 (human)
|
hROCK1/Deam:2
|
"A Rho-associated protein kinase 1 (human) that has been deaminated on the residue at the position equivalent to Asn-644 of the amino acid sequence represented by UniProtKB:Q13464. UniProtKB:Q13464, Asn-644, MOD:00684." [IEDB_epitope:1981270, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:Q63644 |
Rho-associated protein kinase 1 (rat)
|
rROCK1
|
"A Rho-associated protein kinase 1 that is encoded in the genome of rat." [OMA:Q63644, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q63644-1 |
Rho-associated protein kinase 1 isoform r1 (rat)
|
rROCK1/iso:r1
|
"A Rho-associated protein kinase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63644-1." [PRO:DNx, UniProtKB:Q63644]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q63644-2 |
Rho-associated protein kinase 1 isoform r2 (rat)
|
rROCK1/iso:r2
|
"A Rho-associated protein kinase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63644-2." [PRO:DNx, UniProtKB:Q63644]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
sequence
|
|
PR:000000307 |
Rho-associated protein kinase 1 isoform 1
|
ROCK1/iso:1
|
"A Rho-associated protein kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13464-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P70335-1 |
Rho-associated protein kinase 1 isoform 1 (mouse)
|
mROCK1/iso:1
|
"A Rho-associated protein kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036476 |
Rho-associated protein kinase 1 isoform 1 cleaved 1 (mouse)
|
mROCK1/iso:1/Clv:1
|
"A Rho-associated protein kinase 1 isoform 1 cleaved 1 in mouse. UniProtKB:P70335-1, 1-1113." [PMID:11283607, PMID:16983089, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q13464-1 |
Rho-associated protein kinase 1 isoform 1 (human)
|
hROCK1/iso:1
|
"A Rho-associated protein kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000026340 |
Rho-associated protein kinase 1 isoform 1 cleaved 1 (human)
|
hROCK1/iso:1/Clv:1
|
"A Rho-associated protein kinase 1 isoform 1 cleaved 1 in human. UniProtKB:Q13464-1, 1-1113." [PRO:DNx, UniProtKB:Q13464]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000044586 |
Rho-associated protein kinase 1 isoform 1 unmodified form (human)
|
hROCK1/iso:1/UnMod
|
"A Rho-associated protein kinase 1 isoform 1 unmodified form in human." [PRO:DNx]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000563 |
Rho-associated protein kinase 1 isoform 1 cleaved 1
|
ROCK1/iso:1/Clv:1
|
"A Rho-associated protein kinase 1 isoform 1 that has been processed by caspase-3 downstream the sequence motif DETD, removing the inhibitory C-terminus." [PMID:11283607, PMID:16983089]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000026340 |
Rho-associated protein kinase 1 isoform 1 cleaved 1 (human)
|
hROCK1/iso:1/Clv:1
|
"A Rho-associated protein kinase 1 isoform 1 cleaved 1 in human. UniProtKB:Q13464-1, 1-1113." [PRO:DNx, UniProtKB:Q13464]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036476 |
Rho-associated protein kinase 1 isoform 1 cleaved 1 (mouse)
|
mROCK1/iso:1/Clv:1
|
"A Rho-associated protein kinase 1 isoform 1 cleaved 1 in mouse. UniProtKB:P70335-1, 1-1113." [PMID:11283607, PMID:16983089, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000002529 |
Rho-associated protein kinase 1 isoform 1 unmodified form
|
ROCK1/iso:1/UnMod
|
"A Rho-associated protein kinase 1 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000044586 |
Rho-associated protein kinase 1 isoform 1 unmodified form (human)
|
hROCK1/iso:1/UnMod
|
"A Rho-associated protein kinase 1 isoform 1 unmodified form in human." [PRO:DNx]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000026574 |
Rho-associated protein kinase 1 isoform 1, initiator methionine removed form
|
ROCK1/iso:1/InitMet-
|
"A Rho-associated protein kinase 1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
modification
|
|
PR:000018280 |
Rho-associated protein kinase 1, initiator methionine removed form
|
ROCK1/InitMet-
|
"A Rho-associated protein kinase 1 that has had the initiator methionine removed." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000026574 |
Rho-associated protein kinase 1 isoform 1, initiator methionine removed form
|
ROCK1/iso:1/InitMet-
|
"A Rho-associated protein kinase 1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000061208 |
Rho-associated protein kinase 1, initiator methionine removed form (human)
|
hROCK1/InitMet-
|
"A Rho-associated protein kinase 1 (human) that has had the initiator methionine removed. UniProtKB:Q13464, 2-1354." [PRO:DNx, Reactome:R-HSA-212509, Reactome:R-HSA-6804967, Reactome:R-HSA-6806527]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
modification
|
|
PR:000025435 |
Rho-associated protein kinase 1 proteolytic cleavage product
|
ROCK1/ClvPrd
|
"A Rho-associated protein kinase 1 that has been processed by proteolytic cleavage." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000563 |
Rho-associated protein kinase 1 isoform 1 cleaved 1
|
ROCK1/iso:1/Clv:1
|
"A Rho-associated protein kinase 1 isoform 1 that has been processed by caspase-3 downstream the sequence motif DETD, removing the inhibitory C-terminus." [PMID:11283607, PMID:16983089]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000026340 |
Rho-associated protein kinase 1 isoform 1 cleaved 1 (human)
|
hROCK1/iso:1/Clv:1
|
"A Rho-associated protein kinase 1 isoform 1 cleaved 1 in human. UniProtKB:Q13464-1, 1-1113." [PRO:DNx, UniProtKB:Q13464]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036476 |
Rho-associated protein kinase 1 isoform 1 cleaved 1 (mouse)
|
mROCK1/iso:1/Clv:1
|
"A Rho-associated protein kinase 1 isoform 1 cleaved 1 in mouse. UniProtKB:P70335-1, 1-1113." [PMID:11283607, PMID:16983089, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | |
| | | | | | |
gene
|
|
PR:000000121 |
Rho-associated protein kinase 2
|
ROCK2
|
"A Rho-associated protein kinase that is a translation product of the human ROCK2 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:O75116 |
Rho-associated protein kinase 2 (human)
|
hROCK2
|
"A Rho-associated protein kinase 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O75116]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:O75116-1 |
Rho-associated protein kinase 2 isoform 1 (human)
|
hROCK2/iso:1
|
"A Rho-associated protein kinase 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036477 |
Rho-associated protein kinase 2 isoform 1 cleaved 1 (human)
|
hROCK2/iso:1/Clv:1
|
"A Rho-associated protein kinase 2 isoform 1 cleaved 1 in human. UniProtKB:O75116-1, 1-1131." [PMID:15699075, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036478 |
Rho-associated protein kinase 2 isoform 1 phosphorylated 1 (human)
|
hROCK2/iso:1/Phos:1
|
"A Rho-associated protein kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:O75116-1, Ser-1134/Ser-1137, MOD:00046." [PMID:15302935, PMID:17446864, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036479 |
Rho-associated protein kinase 2 isoform 1 phosphorylated 2 (human)
|
hROCK2/iso:1/Phos:2
|
"A Rho-associated protein kinase 2 isoform 1 phosphorylated 2 in human. UniProtKB:O75116-1, Thr-1078, MOD:00047." [PMID:17525332, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000066276 |
Rho-associated protein kinase 2 methylated 1 (human)
|
hROCK2/Me:1
|
"A Rho-associated protein kinase 2 (human) that has been methylated on the residue at the position equivalent to Cys-236 of the amino acid sequence represented by UniProtKB:O75116. UniProtKB:O75116, Cys-236, MOD:00660." [IEDB_epitope:1024569, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000071951 |
Rho-associated protein kinase 2 methylated 2 (human)
|
hROCK2/Me:2
|
"A Rho-associated protein kinase 2 (human) that has been methylated on the residue at the position equivalent to Cys-1315 of the amino acid sequence represented by UniProtKB:O75116. UniProtKB:O75116, Cys-1315, MOD:00660." [IEDB_epitope:1020710, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000074887 |
Rho-associated protein kinase 2 phosphorylated 1 (human)
|
hROCK2/Phos:1
|
"A Rho-associated protein kinase 2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-1379 of the amino acid sequence represented by UniProtKB:O75116. UniProtKB:O75116, Ser-1379, MOD:00046." [IEDB_epitope:2147201, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:P70336 |
Rho-associated protein kinase 2 (mouse)
|
mROCK2
|
"A Rho-associated protein kinase 2 that is encoded in the genome of mouse." [OMA:P70336, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P70336-1 |
Rho-associated protein kinase 2 isoform 1 (mouse)
|
mROCK2/iso:1
|
"A Rho-associated protein kinase 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P70336-2 |
Rho-associated protein kinase 2 isoform 2 (mouse)
|
mROCK2/iso:2
|
"A Rho-associated protein kinase 2 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:Q62868 |
Rho-associated protein kinase 2 (rat)
|
rROCK2
|
"A Rho-associated protein kinase 2 that is encoded in the genome of rat." [OMA:Q62868, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
sequence
|
|
PR:000000308 |
Rho-associated protein kinase 2 isoform 1
|
ROCK2/iso:1
|
"A Rho-associated protein kinase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75116-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:O75116-1 |
Rho-associated protein kinase 2 isoform 1 (human)
|
hROCK2/iso:1
|
"A Rho-associated protein kinase 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036477 |
Rho-associated protein kinase 2 isoform 1 cleaved 1 (human)
|
hROCK2/iso:1/Clv:1
|
"A Rho-associated protein kinase 2 isoform 1 cleaved 1 in human. UniProtKB:O75116-1, 1-1131." [PMID:15699075, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036478 |
Rho-associated protein kinase 2 isoform 1 phosphorylated 1 (human)
|
hROCK2/iso:1/Phos:1
|
"A Rho-associated protein kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:O75116-1, Ser-1134/Ser-1137, MOD:00046." [PMID:15302935, PMID:17446864, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036479 |
Rho-associated protein kinase 2 isoform 1 phosphorylated 2 (human)
|
hROCK2/iso:1/Phos:2
|
"A Rho-associated protein kinase 2 isoform 1 phosphorylated 2 in human. UniProtKB:O75116-1, Thr-1078, MOD:00047." [PMID:17525332, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P70336-1 |
Rho-associated protein kinase 2 isoform 1 (mouse)
|
mROCK2/iso:1
|
"A Rho-associated protein kinase 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000462 |
Rho-associated protein kinase 2 isoform 1 phosphorylated form
|
ROCK2/iso:1/PhosRes+
|
"A Rho-associated protein kinase 2 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000565 |
Rho-associated protein kinase 2 isoform 1 phosphorylated 1
|
ROCK2/iso:1/Phos:1
|
"A Rho-associated protein kinase 2 isoform 1 phosphorylated form in which the phosphorylation occurs within the C-terminal region by the action of serine/threonine-protein kinase PLK1." [PMID:17446864]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036478 |
Rho-associated protein kinase 2 isoform 1 phosphorylated 1 (human)
|
hROCK2/iso:1/Phos:1
|
"A Rho-associated protein kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:O75116-1, Ser-1134/Ser-1137, MOD:00046." [PMID:15302935, PMID:17446864, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000566 |
Rho-associated protein kinase 2 isoform 1 phosphorylated 2
|
ROCK2/iso:1/Phos:2
|
"A Rho-associated protein kinase 2 isoform 1 phosphorylated form that has been induced by DNA damage. Example: UniProtKB:O75116-1, Thr-1078, MOD:00047." [PMID:17525332, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036479 |
Rho-associated protein kinase 2 isoform 1 phosphorylated 2 (human)
|
hROCK2/iso:1/Phos:2
|
"A Rho-associated protein kinase 2 isoform 1 phosphorylated 2 in human. UniProtKB:O75116-1, Thr-1078, MOD:00047." [PMID:17525332, PRO:CNA]
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Yes |
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modification
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PR:000000564 |
Rho-associated protein kinase 2 isoform 1 cleaved 1
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ROCK2/iso:1/Clv:1
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"A Rho-associated protein kinase 2 isoform 1 that has been cleaved in the granzyme B consensus motif [IVL][GE]xD located between the Rho binding and the PH domains, removing the C-terminus." [PRO:CNA]
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organism-modification
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PR:000036477 |
Rho-associated protein kinase 2 isoform 1 cleaved 1 (human)
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hROCK2/iso:1/Clv:1
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"A Rho-associated protein kinase 2 isoform 1 cleaved 1 in human. UniProtKB:O75116-1, 1-1131." [PMID:15699075, PRO:CNA]
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Yes |
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modification
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PR:000002530 |
Rho-associated protein kinase 2 isoform 1 unmodified form
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ROCK2/iso:1/UnMod
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"A Rho-associated protein kinase 2 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
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sequence
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PR:000000309 |
Rho-associated protein kinase 2 isoform 2
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ROCK2/iso:2
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"A Rho-associated protein kinase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70336-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:P70336-2 |
Rho-associated protein kinase 2 isoform 2 (mouse)
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mROCK2/iso:2
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"A Rho-associated protein kinase 2 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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modification
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PR:000025436 |
Rho-associated protein kinase 2 proteolytic cleavage product
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ROCK2/ClvPrd
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"A Rho-associated protein kinase 2 that has been processed by proteolytic cleavage." [PRO:DNx]
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modification
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PR:000000564 |
Rho-associated protein kinase 2 isoform 1 cleaved 1
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ROCK2/iso:1/Clv:1
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"A Rho-associated protein kinase 2 isoform 1 that has been cleaved in the granzyme B consensus motif [IVL][GE]xD located between the Rho binding and the PH domains, removing the C-terminus." [PRO:CNA]
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organism-modification
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PR:000036477 |
Rho-associated protein kinase 2 isoform 1 cleaved 1 (human)
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hROCK2/iso:1/Clv:1
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"A Rho-associated protein kinase 2 isoform 1 cleaved 1 in human. UniProtKB:O75116-1, 1-1131." [PMID:15699075, PRO:CNA]
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Yes |
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