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 |
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| | |
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family
|
|
PR:000000023 |
retinoblastoma-like protein
|
NOG
|
"A protein that has a core domain composition consisting of a Retinoblastoma-associated protein A domain (Pfam:PF01858) followed by a Retinoblastoma-associated protein B domain (Pfam:PF01857). The retinoblastoma-like proteins are key regulators of entry into cell division. They are directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | |
| | | | | | |
gene
|
|
PR:000000118 |
retinoblastoma-like protein 1
|
RBL1
|
"A retinoblastoma-like protein that is a translation product of the human RBL1 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:D3ZS28 |
retinoblastoma-like protein 1 (rat)
|
rRBL1
|
"A retinoblastoma-like protein 1 that is encoded in the genome of rat." [OMA:D3ZS28, PRO:DNx]
|
|
|
|
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|
| | | | | | |
| | | | |
organism-gene
|
|
PR:P28749 |
retinoblastoma-like protein 1 (human)
|
hRBL1
|
"A retinoblastoma-like protein 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P28749]
|
|
|
|
|
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|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P28749-1 |
retinoblastoma-like protein 1 isoform 1 (human)
|
hRBL1/iso:1
|
"A retinoblastoma-like protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036470 |
retinoblastoma-like protein 1 isoform 1 phosphorylated 1 (human)
|
hRBL1/iso:1/Phos:1
|
"A retinoblastoma-like protein 1 isoform 1 phosphorylated 1 in human. UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046." [PMID:11884610, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P28749-2 |
retinoblastoma-like protein 1 isoform 2 (human)
|
hRBL1/iso:2
|
"A retinoblastoma-like protein 1 isoform 2 that is encoded in the genome of human." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000049024 |
retinoblastoma-like protein 1 phosphorylated 1 (human)
|
hRBL1/Phos:1
|
"A retinoblastoma-like protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-369, and phosphoserine at positions 640, 964 and 975 of the amino acid sequence represented by UniProtKB:P28749. UniProtKB:P28749, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046." [PRO:DNx, Reactome:R-HSA-1226085]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:Q24472 |
retinoblastoma family protein (fruit fly)
|
fly-RBL1
|
"A retinoblastoma-like protein 1 that is encoded in the genome of fruit fly." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:Q64701 |
retinoblastoma-like protein 1 (mouse)
|
mRBL1
|
"A retinoblastoma-like protein 1 that is encoded in the genome of mouse." [OMA:Q64701, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q64701-1 |
retinoblastoma-like protein 1 isoform Long (mouse)
|
mRBL1/iso:Long
|
"A retinoblastoma-like protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q64701-2 |
retinoblastoma-like protein 1 isoform Short (mouse)
|
mRBL1/iso:Short
|
"A retinoblastoma-like protein 1 isoform 3 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
sequence
|
|
PR:000000303 |
retinoblastoma-like protein 1 isoform 1
|
RBL1/iso:1
|
"A retinoblastoma-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28749-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P28749-1 |
retinoblastoma-like protein 1 isoform 1 (human)
|
hRBL1/iso:1
|
"A retinoblastoma-like protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036470 |
retinoblastoma-like protein 1 isoform 1 phosphorylated 1 (human)
|
hRBL1/iso:1/Phos:1
|
"A retinoblastoma-like protein 1 isoform 1 phosphorylated 1 in human. UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046." [PMID:11884610, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q64701-1 |
retinoblastoma-like protein 1 isoform Long (mouse)
|
mRBL1/iso:Long
|
"A retinoblastoma-like protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000458 |
retinoblastoma-like protein 1 isoform 1 phosphorylated form
|
RBL1/iso:1/PhosRes+
|
"A retinoblastoma-like protein 1 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000559 |
retinoblastoma-like protein 1 isoform 1 phosphorylated 1
|
RBL1/iso:1/Phos:1
|
"A retinoblastoma-like protein 1 isoform 1 phosphorylated form in which the phosphorylation occurs in an RxL motif-dependent fashion by cyclin Cdk4. Example: UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046." [PMID:11884610, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036470 |
retinoblastoma-like protein 1 isoform 1 phosphorylated 1 (human)
|
hRBL1/iso:1/Phos:1
|
"A retinoblastoma-like protein 1 isoform 1 phosphorylated 1 in human. UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046." [PMID:11884610, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
sequence
|
|
PR:000000304 |
retinoblastoma-like protein 1 isoform 2
|
RBL1/iso:2
|
"A retinoblastoma-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28749-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P28749-2 |
retinoblastoma-like protein 1 isoform 2 (human)
|
hRBL1/iso:2
|
"A retinoblastoma-like protein 1 isoform 2 that is encoded in the genome of human." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
sequence
|
|
PR:000000305 |
retinoblastoma-like protein 1 isoform 3
|
RBL1/iso:3
|
"A retinoblastoma-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64701-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q64701-2 |
retinoblastoma-like protein 1 isoform Short (mouse)
|
mRBL1/iso:Short
|
"A retinoblastoma-like protein 1 isoform 3 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | |
| | | | | | |
gene
|
|
PR:000000119 |
retinoblastoma-like protein 2
|
RBL2
|
"A retinoblastoma-like protein that is a translation product of the human RBL2 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:O55081 |
retinoblastoma-like protein 2 (rat)
|
rRBL2
|
"A retinoblastoma-like protein 2 that is encoded in the genome of rat." [OMA:O55081, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:Q08999 |
retinoblastoma-like protein 2 (human)
|
hRBL2
|
"A retinoblastoma-like protein 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q08999]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q08999-1 |
retinoblastoma-like protein 2 isoform 1 (human)
|
hRBL2/iso:1
|
"A retinoblastoma-like protein 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036471 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 1 (human)
|
hRBL2/iso:1/Phos:1
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 1 in human. UniProtKB:Q08999-1, Thr-401/Thr-417/Thr-642/Thr-694/Thr-986/Thr-1097, MOD:00047|Ser-413/Ser-639/Ser-662/Ser-672/Ser-688/Ser-948/Ser-952/Ser-962/Ser-966/Ser-973/Ser-982/Ser-1035/Ser-1044/Ser-1068/Ser-1080/Ser-1112, MOD:00046." [PMID:11042701, PMID:11157749, PMID:8710362, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036472 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 2 (human)
|
hRBL2/iso:1/Phos:2
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 2 in human. UniProtKB:Q08999-1, Ser-672, MOD:00046." [PMID:12006580, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036473 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (human)
|
hRBL2/iso:1/Phos:3
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 3 in human. UniProtKB:Q08999-1, Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047." [PMID:11042701, PMID:11157749, PMID:8710362, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q08999-2 |
retinoblastoma-like protein 2 isoform h2 (human)
|
hRBL2/iso:h2
|
"A retinoblastoma-like protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08999-2." [PRO:DNx, UniProtKB:Q08999]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000049025 |
retinoblastoma-like protein 2 phosphorylated 4 (human)
|
hRBL2/Phos:4
|
"A retinoblastoma-like protein 2 (human) that has been phosphorylated on the residue at the position equivalent to Thr-401, and phosphoserine at positions 672 and 1035 of the amino acid sequence represented by UniProtKB:Q08999. UniProtKB:Q08999, Thr-401, MOD:00047|Ser-672/Ser-1035, MOD:00046." [PRO:DNx, Reactome:R-HSA-1226084]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000068308 |
retinoblastoma-like protein 2 phosphorylated 1 (human)
|
hRBL2/Phos:1
|
"A retinoblastoma-like protein 2 (human) that has been phosphorylated on the residue at the position equivalent to Thr-401 of the amino acid sequence represented by UniProtKB:Q08999-1. Example: UniProtKB:Q08999-1, Thr-401, MOD:00047." [IEDB_epitope:1368331, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:Q64700 |
retinoblastoma-like protein 2 (mouse)
|
mRBL2
|
"A retinoblastoma-like protein 2 that is encoded in the genome of mouse." [OMA:Q64700, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q64700-1 |
retinoblastoma-like protein 2 isoform 1 (mouse)
|
mRBL2/iso:1
|
"A retinoblastoma-like protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036474 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (mouse)
|
mRBL2/iso:1/Phos:3
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 3 in mouse." [PMID:10082561, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
sequence
|
|
PR:000000306 |
retinoblastoma-like protein 2 isoform 1
|
RBL2/iso:1
|
"A retinoblastoma-like protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08999-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q08999-1 |
retinoblastoma-like protein 2 isoform 1 (human)
|
hRBL2/iso:1
|
"A retinoblastoma-like protein 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036471 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 1 (human)
|
hRBL2/iso:1/Phos:1
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 1 in human. UniProtKB:Q08999-1, Thr-401/Thr-417/Thr-642/Thr-694/Thr-986/Thr-1097, MOD:00047|Ser-413/Ser-639/Ser-662/Ser-672/Ser-688/Ser-948/Ser-952/Ser-962/Ser-966/Ser-973/Ser-982/Ser-1035/Ser-1044/Ser-1068/Ser-1080/Ser-1112, MOD:00046." [PMID:11042701, PMID:11157749, PMID:8710362, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036472 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 2 (human)
|
hRBL2/iso:1/Phos:2
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 2 in human. UniProtKB:Q08999-1, Ser-672, MOD:00046." [PMID:12006580, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036473 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (human)
|
hRBL2/iso:1/Phos:3
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 3 in human. UniProtKB:Q08999-1, Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047." [PMID:11042701, PMID:11157749, PMID:8710362, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q64700-1 |
retinoblastoma-like protein 2 isoform 1 (mouse)
|
mRBL2/iso:1
|
"A retinoblastoma-like protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036474 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (mouse)
|
mRBL2/iso:1/Phos:3
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 3 in mouse." [PMID:10082561, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000459 |
retinoblastoma-like protein 2 isoform 1 phosphorylated form
|
RBL2/iso:1/PhosRes+
|
"A retinoblastoma-like protein 2 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000560 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 1
|
RBL2/iso:1/Phos:1
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated form in which the phosphorylation occurs during Go/G1-S phase progression. Example: UniProtKB:Q08999-1, Thr-401/Thr-417/Thr-642/Thr-694/Thr-986/Thr-1097, MOD:00047|Ser-413/Ser-639/Ser-662/Ser-672/Ser-688/Ser-948/Ser-952/Ser-962/Ser-966/Ser-973/Ser-982/Ser-1035/Ser-1044/Ser-1068/Ser-1080/Ser-1112, MOD:00046." [PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036471 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 1 (human)
|
hRBL2/iso:1/Phos:1
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 1 in human. UniProtKB:Q08999-1, Thr-401/Thr-417/Thr-642/Thr-694/Thr-986/Thr-1097, MOD:00047|Ser-413/Ser-639/Ser-662/Ser-672/Ser-688/Ser-948/Ser-952/Ser-962/Ser-966/Ser-973/Ser-982/Ser-1035/Ser-1044/Ser-1068/Ser-1080/Ser-1112, MOD:00046." [PMID:11042701, PMID:11157749, PMID:8710362, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000561 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 2
|
RBL2/iso:1/Phos:2
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated form that has Cdk-dependent G1 phosphorylation, and additionally phosphorylated on a Ser residue within the region linking the retinoblastoma-associated protein A and B domains, by cyclin Cdk4(6). This phosphorylation leads to ubiquitin-dependent proteolysis." [PMID:12006580, PMID:12435635]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036472 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 2 (human)
|
hRBL2/iso:1/Phos:2
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 2 in human. UniProtKB:Q08999-1, Ser-672, MOD:00046." [PMID:12006580, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000562 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 3
|
RBL2/iso:1/Phos:3
|
"A retinoblastoma-like protein 2 isoform 1 that has been phosphorylated on residues at positions equivalent to Ser-639, Ser-952, Ser-966, Ser-971, Ser-972, Ser-973, Thr-974, Ser-981, Ser-982, and Thr-986 of the amino acid sequence represented by UniProtKB:Q08999-1 or a 1:1 ortholog thereof. Example: UniProtKB:Q08999-1, Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047." [PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036473 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (human)
|
hRBL2/iso:1/Phos:3
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 3 in human. UniProtKB:Q08999-1, Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047." [PMID:11042701, PMID:11157749, PMID:8710362, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036474 |
retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (mouse)
|
mRBL2/iso:1/Phos:3
|
"A retinoblastoma-like protein 2 isoform 1 phosphorylated 3 in mouse." [PMID:10082561, PRO:CNA]
|
Yes |
|
|
|
