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 |
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| | |
| | | | | | |
family
|
|
PR:000000022 |
ptx homeobox protein
|
NOG
|
"A protein that has a core domain composition consisting of an N-terminal K50 class Homeobox domain (Pfam:PF00046) and a C-terminal OAR domain (Pfam:PF03826). The homeobox domain consists of a self-folding, stable protein domain of 60 amino acids in which position 50 can confer a distinct DNA binding specificity. The K50 class of homeodomains recognizes a consensus DNA sequence of TAATCC. Homeodomain-containing proteins are known to play important roles in such diverse activities as embryonic pattern formation, cell-type specification, and differentiation." [PMID:15895993]
|
Yes |
|
|
|
|
|
| | | | |
| | | | |
gene
|
|
PR:000000117 |
pituitary homeobox 2
|
PITX2
|
"A ptx homeobox protein that is a translation product of the human PITX2 gene or a 1:1 ortholog thereof. The PITX2 gene contains 6 conserved exons." [PRO:CNA]
|
|
|
|
|
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|
| | | | | | |
| | |
organism-gene
|
|
PR:O93385 |
pituitary homeobox 2 (chicken)
|
chick-PITX2
|
"A pituitary homeobox 2 that is encoded in the genome of chicken." [OMA:O93385, PRO:CNA]
|
|
|
|
|
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|
| | | | | | | | |
|
organism-sequence
|
|
PR:O93385-1 |
pituitary homeobox 2 isoform Ptx2C (chicken)
|
chick-PITX2/iso:Ptx2C
|
"A pituitary homeobox 2 isoform Ptx2C that is encoded in the genome of chicken." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:O93385-2 |
pituitary homeobox 2 isoform Ptx2A (chicken)
|
chick-PITX2/iso:Ptx2A
|
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of chicken." [PRO:DNx, UniProtKB:O93385]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-gene
|
|
PR:P97474 |
pituitary homeobox 2 (mouse)
|
mPITX2
|
"A pituitary homeobox 2 that is encoded in the genome of mouse." [OMA:P97474, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:000036295 |
pituitary homeobox 2 isoform 4 (mouse)
|
mPITX2/iso:4
|
"A pituitary homeobox 2 isoform 4 that is encoded in the genome of mouse." [PMID:11948188, PRO:DAN]
|
|
|
|
|
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|
| | | | | | | | |
|
organism-sequence
|
|
PR:P97474-1 |
pituitary homeobox 2 isoform Ptx2B (mouse)
|
mPITX2/iso:Ptx2B
|
"A pituitary homeobox 2 isoform Ptx2B that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P97474]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:P97474-2 |
pituitary homeobox 2 isoform Ptx2C (mouse)
|
mPITX2/iso:Ptx2C
|
"A pituitary homeobox 2 isoform Ptx2C that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P97474]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:P97474-3 |
pituitary homeobox 2 isoform Ptx2A (mouse)
|
mPITX2/iso:Ptx2A
|
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P97474]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:P97474-4 |
pituitary homeobox 2 isoform Ptx2Calpha (mouse)
|
mPITX2/iso:Ptx2Calpha
|
"A pituitary homeobox 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97474-4." [PRO:DNx, UniProtKB:P97474]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:P97474-5 |
pituitary homeobox 2 isoform Ptx2Cbeta (mouse)
|
mPITX2/iso:Ptx2Cbeta
|
"A pituitary homeobox 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97474-5." [PRO:DNx, UniProtKB:P97474]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-gene
|
|
PR:Q99697 |
pituitary homeobox 2 (human)
|
hPITX2
|
"A pituitary homeobox 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q99697]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:000000298 |
pituitary homeobox 2 sequence variant R89W (human)
|
hPITX2/var:R89W
|
"A pituitary homeobox 2 (human) that has a Trp residue at the position equivalent to Arg-89 of the amino acid sequence represented by UniProtKB:Q99697-1. Example: UniProtKB:Q99697-1, Arg-89, CHEBI:29954." [PMID:9437321, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:000000299 |
pituitary homeobox 2 sequence variant L100Q (human)
|
hPITX2/var:L100Q
|
"A pituitary homeobox 2 (human) that has a Gln residue at the position equivalent to Leu-100 of the amino acid sequence represented by UniProtKB:Q99697-1. Example: UniProtKB:Q99697-1, Leu-100, CHEBI:30011." [PMID:8944018, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:000000300 |
pituitary homeobox 2 sequence variant T114P (human)
|
hPITX2/var:T114P
|
"A pituitary homeobox 2 (human) that has a Pro residue at the position equivalent to Thr-114 of the amino acid sequence represented by UniProtKB:Q99697-1. Example: UniProtKB:Q99697-1, Thr-114, CHEBI:50342." [PMID:8944018, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:000000301 |
pituitary homeobox 2 sequence variant R115H (human)
|
hPITX2/var:R115H
|
"A pituitary homeobox 2 (human) that has a His residue at the position equivalent to Arg-115 of the amino acid sequence represented by UniProtKB:Q99697-1. Example: UniProtKB:Q99697-1, Arg-115, CHEBI:29979." [PMID:9618168, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:000000302 |
pituitary homeobox 2 sequence variant R137P (human)
|
hPITX2/var:R137P
|
"A pituitary homeobox 2 (human) that has a Pro residue at the position equivalent to Arg-137 of the amino acid sequence represented by UniProtKB:Q99697-1. Example: UniProtKB:Q99697-1, Arg-137, CHEBI:50342." [PMID:8944018, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:000036294 |
pituitary homeobox 2 isoform 4 (human)
|
hPITX2/iso:4
|
"A pituitary homeobox 2 isoform 4 that is encoded in the genome of human." [PMID:11948188, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:Q99697-1 |
pituitary homeobox 2 isoform Ptx2B (human)
|
hPITX2/iso:Ptx2B
|
"A pituitary homeobox 2 isoform Ptx2B that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99697]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:Q99697-2 |
pituitary homeobox 2 isoform Ptx2C (human)
|
hPITX2/iso:Ptx2C
|
"A pituitary homeobox 2 isoform Ptx2C that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99697]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:Q99697-3 |
pituitary homeobox 2 isoform Ptx2A (human)
|
hPITX2/iso:Ptx2A
|
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99697]
|
Yes |
|
|
|
|
|
| | | | | | |
| | |
organism-gene
|
|
PR:Q9R0W1 |
pituitary homeobox 2 (rat)
|
rPITX2
|
"A pituitary homeobox 2 that is encoded in the genome of rat." [OMA:Q9R0W1, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:Q9R0W1-1 |
pituitary homeobox 2 isoform Ptx2C (rat)
|
rPITX2/iso:Ptx2C
|
"A pituitary homeobox 2 isoform Ptx2C that is encoded in the genome of rat." [PRO:DNx, UniProtKB:Q9R0W1]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:Q9R0W1-2 |
pituitary homeobox 2 isoform Ptx2A (rat)
|
rPITX2/iso:Ptx2A
|
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of rat." [PRO:DNx, UniProtKB:Q9R0W1]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-gene
|
|
PR:Q9W5Z2 |
pituitary homeobox 2 (zebrafish)
|
z-PITX2
|
"A pituitary homeobox 2 that is encoded in the genome of zebrafish." [OMA:Q9W5Z2, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:Q9W5Z2-1 |
pituitary homeobox 2 isoform c (zebrafish)
|
z-PITX2/iso:c
|
"A pituitary homeobox 2 (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9W5Z2-1." [PRO:DNx, UniProtKB:Q9W5Z2]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:Q9W5Z2-2 |
pituitary homeobox 2 isoform a (zebrafish)
|
z-PITX2/iso:a
|
"A pituitary homeobox 2 (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9W5Z2-2." [PRO:DNx, UniProtKB:Q9W5Z2]
|
|
|
|
|
|
|
| | | | | | |
| | |
sequence
|
|
PR:000000294 |
pituitary homeobox 2 isoform Ptx2A
|
PITX2/iso:Ptx2A
|
"A pituitary homeobox 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99697-3 or a 1:1 ortholog thereof." [PMID:10585561, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:O93385-2 |
pituitary homeobox 2 isoform Ptx2A (chicken)
|
chick-PITX2/iso:Ptx2A
|
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of chicken." [PRO:DNx, UniProtKB:O93385]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:P97474-3 |
pituitary homeobox 2 isoform Ptx2A (mouse)
|
mPITX2/iso:Ptx2A
|
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P97474]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:Q99697-3 |
pituitary homeobox 2 isoform Ptx2A (human)
|
hPITX2/iso:Ptx2A
|
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99697]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:Q9R0W1-2 |
pituitary homeobox 2 isoform Ptx2A (rat)
|
rPITX2/iso:Ptx2A
|
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of rat." [PRO:DNx, UniProtKB:Q9R0W1]
|
|
|
|
|
|
|
| | | | | | |
| | |
sequence
|
|
PR:000000295 |
pituitary homeobox 2 isoform Ptx2B
|
PITX2/iso:Ptx2B
|
"A pituitary homeobox 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99697-1 or a 1:1 ortholog thereof." [PMID:10585561, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:P97474-1 |
pituitary homeobox 2 isoform Ptx2B (mouse)
|
mPITX2/iso:Ptx2B
|
"A pituitary homeobox 2 isoform Ptx2B that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P97474]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:Q99697-1 |
pituitary homeobox 2 isoform Ptx2B (human)
|
hPITX2/iso:Ptx2B
|
"A pituitary homeobox 2 isoform Ptx2B that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99697]
|
Yes |
|
|
|
|
|
| | | | | | |
| | |
sequence
|
|
PR:000000296 |
pituitary homeobox 2 isoform Ptx2C
|
PITX2/iso:Ptx2C
|
"A pituitary homeobox 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99697-2 or a 1:1 ortholog thereof." [PMID:10585561, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:O93385-1 |
pituitary homeobox 2 isoform Ptx2C (chicken)
|
chick-PITX2/iso:Ptx2C
|
"A pituitary homeobox 2 isoform Ptx2C that is encoded in the genome of chicken." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:P97474-2 |
pituitary homeobox 2 isoform Ptx2C (mouse)
|
mPITX2/iso:Ptx2C
|
"A pituitary homeobox 2 isoform Ptx2C that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P97474]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:Q99697-2 |
pituitary homeobox 2 isoform Ptx2C (human)
|
hPITX2/iso:Ptx2C
|
"A pituitary homeobox 2 isoform Ptx2C that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99697]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:Q9R0W1-1 |
pituitary homeobox 2 isoform Ptx2C (rat)
|
rPITX2/iso:Ptx2C
|
"A pituitary homeobox 2 isoform Ptx2C that is encoded in the genome of rat." [PRO:DNx, UniProtKB:Q9R0W1]
|
|
|
|
|
|
|
| | | | | | |
| | |
sequence
|
|
PR:000000297 |
pituitary homeobox 2 isoform 4
|
PITX2/iso:4
|
"A pituitary homeobox 2 that is a translation product of a transcript that uses an alternative promoter and that results from splicing of exon 4a to a cryptic 3'-splice site in exon 5, which produces a truncated homeodomain and complete C-terminal tail." [PMID:11948188, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:000036294 |
pituitary homeobox 2 isoform 4 (human)
|
hPITX2/iso:4
|
"A pituitary homeobox 2 isoform 4 that is encoded in the genome of human." [PMID:11948188, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:000036295 |
pituitary homeobox 2 isoform 4 (mouse)
|
mPITX2/iso:4
|
"A pituitary homeobox 2 isoform 4 that is encoded in the genome of mouse." [PMID:11948188, PRO:DAN]
|
|
|
|
|
|
|
| | | | |
| | | | |
gene
|
|
PR:000012760 |
pituitary homeobox 1
|
PITX1
|
"A ptx homeobox protein that is a translation product of the human PITX1 gene or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-gene
|
|
PR:P70314 |
pituitary homeobox 1 (mouse)
|
mPITX1
|
"A pituitary homeobox 1 that is encoded in the genome of mouse." [OMA:P70314, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-gene
|
|
PR:P78337 |
pituitary homeobox 1 (human)
|
hPITX1
|
"A pituitary homeobox 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P78337]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-gene
|
|
PR:Q99NA7 |
pituitary homeobox 1 (rat)
|
rPITX1
|
"A pituitary homeobox 1 that is encoded in the genome of rat." [OMA:Q99NA7, PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | |
gene
|
|
PR:000012761 |
pituitary homeobox 3
|
PITX3
|
"A ptx homeobox protein that is a translation product of the human PITX3 gene or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-gene
|
|
PR:O35160 |
pituitary homeobox 3 (mouse)
|
mPITX3
|
"A pituitary homeobox 3 that is encoded in the genome of mouse." [OMA:O35160, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:O35160-1 |
pituitary homeobox 3 isoform 1 (mouse)
|
mPITX3/iso:1
|
"A pituitary homeobox 3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-gene
|
|
PR:O75364 |
pituitary homeobox 3 (human)
|
hPITX3
|
"A pituitary homeobox 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O75364]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:O75364-1 |
pituitary homeobox 3 isoform 1 (human)
|
hPITX3/iso:1
|
"A pituitary homeobox 3 isoform 1 that is encoded in the genome of human." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-gene
|
|
PR:P81062 |
pituitary homeobox 3 (rat)
|
rPITX3
|
"A pituitary homeobox 3 that is encoded in the genome of rat." [OMA:P81062, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:P81062-1 |
pituitary homeobox 3 isoform 1 (rat)
|
rPITX3/iso:1
|
"A pituitary homeobox 3 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-gene
|
|
PR:Q24256 |
homeobox protein B-H2 (fruit fly)
|
fly-PITX3
|
"A pituitary homeobox 3 that is encoded in the genome of fruit fly." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | |
sequence
|
|
PR:000038343 |
pituitary homeobox 3 isoform 1
|
PITX3/iso:1
|
"A pituitary homeobox 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75364-1 or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:O35160-1 |
pituitary homeobox 3 isoform 1 (mouse)
|
mPITX3/iso:1
|
"A pituitary homeobox 3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:O75364-1 |
pituitary homeobox 3 isoform 1 (human)
|
hPITX3/iso:1
|
"A pituitary homeobox 3 isoform 1 that is encoded in the genome of human." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-sequence
|
|
PR:P81062-1 |
pituitary homeobox 3 isoform 1 (rat)
|
rPITX3/iso:1
|
"A pituitary homeobox 3 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
|
|
|
|
|
