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family
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PR:000000007 |
TGF-beta superfamily receptor type-2 with activin receptor domain
|
TGFBR2
|
"A protein that is a translation product of an evolutionary-related gene with core domain composition consisting of an extracellular Activin types I and II receptor domain (Pfam:PF01064), a transmembrane domain, and a Protein kinase domain (Pfam:PF00069). The transforming growth factor-beta (TGF-beta) superfamily of receptors comprises two groups of transmembrane serine-threonine kinase receptors, so called type-1, and type-2 receptors, that are activated following engagement by members of the TGF-beta superfamily of ligands. These events specify diverse downstream responses that are differentially regulated by controlling access and activation of the ligands, their receptors and downstream substrates in different cell types." [PRO:CNA]
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Yes |
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gene
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PR:000000037 |
BMP receptor type-2
|
BMPR2
|
"A TGF-beta superfamily receptor type-2 with activin receptor domain that is a translation product of the human BMPR2 gene or a 1:1 ortholog thereof. Bone morphogenetic protein (BMP) signals are transmitted by type 2 and type 1 serine/threonine kinase receptors. Type 2 receptors phosphorylate and activate type 1 receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators." [PRO:CNA]
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Yes |
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organism-gene
|
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PR:O35607 |
bone morphogenetic protein receptor type-2 (mouse)
|
mBMPR2
|
"A BMP receptor type-2 that is encoded in the genome of mouse." [OMA:O35607, PRO:DNx]
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organism-sequence
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PR:O35607-1 |
bone morphogenetic protein receptor type-2 isoform 1 (mouse)
|
mBMPR2/iso:1
|
"A BMP receptor type-2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
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organism-gene
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PR:Q13873 |
bone morphogenetic protein receptor type-2 (human)
|
hBMPR2
|
"A BMP receptor type-2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q13873]
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organism-sequence
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PR:000000149 |
BMP receptor type-2 sequence variant C60Y (human)
|
hBMPR2/var:C60Y
|
"A bone morphogenetic protein receptor type-2 (human) that has a Tyr residue at the position equivalent to Cys-60 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-60, CHEBI:46858." [PMID:11015450, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
|
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PR:000000150 |
BMP receptor type-2 sequence variant D485G (human)
|
hBMPR2/var:D485G
|
"A bone morphogenetic protein receptor type-2 (human) that has a Gly residue at the position equivalent to Asp-485 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Asp-485, CHEBI:29947." [PMID:10973254, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
|
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PR:000000151 |
BMP receptor type-2 sequence variant R491Q (human)
|
hBMPR2/var:R491Q
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"A bone morphogenetic protein receptor type-2 (human) that has a Gln residue at the position equivalent to Arg-491 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Arg-491, CHEBI:30011." [PMID:10903931, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
|
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PR:000000152 |
BMP receptor type-2 sequence variant R491W (human)
|
hBMPR2/var:R491W
|
"A bone morphogenetic protein receptor type-2 (human) that has a Trp residue at the position equivalent to Arg-491 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Arg-491, CHEBI:29954." [PMID:10903931, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
|
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PR:000000153 |
BMP receptor type-2 sequence variant K512T (human)
|
hBMPR2/var:K512T
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"A bone morphogenetic protein receptor type-2 (human) that has a Thr residue at the position equivalent to Lys-512 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Lys-512, CHEBI:30013." [PMID:11115378, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000154 |
BMP receptor type-2 sequence variant N519K (human)
|
hBMPR2/var:N519K
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"A bone morphogenetic protein receptor type-2 (human) that has a Lys residue at the position equivalent to Asn-519 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Asn-519, CHEBI:29967." [PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000155 |
BMP receptor type-2 sequence variant C117Y (human)
|
hBMPR2/var:C117Y
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"A bone morphogenetic protein receptor type-2 (human) that has a Tyr residue at the position equivalent to Cys-117 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-117, CHEBI:46858." [PMID:11015450, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000156 |
BMP receptor type-2 sequence variant C118W (human)
|
hBMPR2/var:C118W
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"A bone morphogenetic protein receptor type-2 (human) that has a Trp residue at the position equivalent to Cys-118 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-118, CHEBI:29954." [PMID:10973254, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
|
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PR:000000157 |
BMP receptor type-2 sequence variant C123R (human)
|
hBMPR2/var:C123R
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"A bone morphogenetic protein receptor type-2 (human) that has an Arg residue at the position equivalent to Cys-123 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-123, CHEBI:29952." [PMID:11115378, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
|
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PR:000000158 |
BMP receptor type-2 sequence variant C123S (human)
|
hBMPR2/var:C123S
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"A bone morphogenetic protein receptor type-2 (human) that has a Ser residue at the position equivalent to Cys-123 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-123, CHEBI:29999." [PMID:11115378, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
|
|
PR:000000159 |
BMP receptor type-2 sequence variant E224D (human)
|
hBMPR2/var:E224D
|
"A bone morphogenetic protein receptor type-2 (human) that has an Asp residue at the position equivalent to Glu-224 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Glu-224, CHEBI:29958." [PMID:11115378, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
|
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PR:000000160 |
BMP receptor type-2 sequence variant C347Y (human)
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hBMPR2/var:C347Y
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"A bone morphogenetic protein receptor type-2 (human) that has a Tyr residue at the position equivalent to Cys-347 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-347, CHEBI:46858." [PMID:10973254, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
|
|
PR:000000161 |
BMP receptor type-2 sequence variant C420R (human)
|
hBMPR2/var:C420R
|
"A bone morphogenetic protein receptor type-2 (human) that has an Arg residue at the position equivalent to Cys-420 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-420, CHEBI:29952." [PMID:11115378, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
|
|
PR:000000162 |
BMP receptor type-2 sequence variant C483R (human)
|
hBMPR2/var:C483R
|
"A bone morphogenetic protein receptor type-2 (human) that has an Arg residue at the position equivalent to Cys-483 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-483, CHEBI:29952." [PMID:11015450, PMID:12358323, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
|
|
PR:Q13873-1 |
bone morphogenetic protein receptor type-2 isoform 1 (human)
|
hBMPR2/iso:1
|
"A BMP receptor type-2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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| | |
organism-sequence
|
|
PR:Q13873-2 |
bone morphogenetic protein receptor type-2 isoform h2 (human)
|
hBMPR2/iso:h2
|
"A bone morphogenetic protein receptor type-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13873-2." [PRO:DNx, UniProtKB:Q13873]
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organism-modification
|
|
PR:000046497 |
bone morphogenetic protein receptor type-2, signal peptide removed form (human)
|
hBMPR2/SigPep-
|
"A bone morphogenetic protein receptor type-2 (human) that has had the signal peptide removed. UniProtKB:Q13873, 27-1038." [PRO:DNx, Reactome:R-HSA-201442]
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organism-modification
|
|
PR:000057061 |
bone morphogenetic protein receptor type-2 N-glycosylated 1 (human)
|
hBMPR2/NGlyco:1
|
"A bone morphogenetic protein receptor type-2 (human) that has been N-glycosylated at the residue equivalent to Asn-827 of the amino acid sequence represented by UniProtKB:Q13873-1, in which the glycan composition is represented by GlyTouCan:G10486CT. Example: UniProtKB:Q13873-1, Asn-827, MOD:00160~GNO:G10486CT." [GlyGen:Q13873-1, PMID:29671580, PRO:DNx]
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organism-modification
|
|
PR:000057062 |
bone morphogenetic protein receptor type-2 O-glycosylated 1 (human)
|
hBMPR2/OGlyco:1
|
"A bone morphogenetic protein receptor type-2 (human) that has been O-glycosylated at the residue equivalent to Thr-137 of the amino acid sequence represented by UniProtKB:Q13873-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q13873-1, Thr-137, MOD:00005~GNO:G43417UB." [GlyGen:Q13873-1, PMID:30459171, PRO:DNx]
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organism-modification
|
|
PR:000065377 |
bone morphogenetic protein receptor type-2 methylated 1 (human)
|
hBMPR2/Me:1
|
"A bone morphogenetic protein receptor type-2 (human) that has been methylated on the residue at the position equivalent to Cys-910 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Cys-910, MOD:00660." [IEDB_epitope:1035856, PRO:DNx]
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organism-modification
|
|
PR:000065967 |
bone morphogenetic protein receptor type-2 deaminated 1 (human)
|
hBMPR2/Deam:1
|
"A bone morphogenetic protein receptor type-2 (human) that has been deaminated on the residue at the position equivalent to Asn-728 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Asn-728, MOD:00684." [IEDB_epitope:1583797, PRO:DNx]
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organism-modification
|
|
PR:000073289 |
bone morphogenetic protein receptor type-2 deaminated 2 (human)
|
hBMPR2/Deam:2
|
"A bone morphogenetic protein receptor type-2 (human) that has been deaminated on the residue at the position equivalent to Asn-861 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Asn-861, MOD:00684." [IEDB_epitope:1738174, PRO:DNx]
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organism-modification
|
|
PR:000081621 |
bone morphogenetic protein receptor type-2 deaminated 3 (human)
|
hBMPR2/Deam:3
|
"A bone morphogenetic protein receptor type-2 (human) that has been deaminated on the residue at the position equivalent to Asn-827 of the amino acid sequence represented by UniProtKB:Q13873-1. Example: UniProtKB:Q13873-1, Asn-827, MOD:00684." [IEDB_epitope:1591068, PRO:DNx]
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|
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sequence
|
|
PR:000000148 |
BMP receptor type-2 isoform 1
|
BMPR2/iso:1
|
"A BMP receptor type-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13873-1 or a 1:1 ortholog thereof." [PRO:CNA]
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| | |
organism-sequence
|
|
PR:O35607-1 |
bone morphogenetic protein receptor type-2 isoform 1 (mouse)
|
mBMPR2/iso:1
|
"A BMP receptor type-2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
|
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| | |
organism-sequence
|
|
PR:Q13873-1 |
bone morphogenetic protein receptor type-2 isoform 1 (human)
|
hBMPR2/iso:1
|
"A BMP receptor type-2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
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gene
|
|
PR:000000070 |
activin receptor type-2A
|
ACVR2A
|
"A TGF-beta superfamily receptor type-2 with activin receptor domain that is a translation product of the human ACVR2A gene or a 1:1 ortholog thereof." [PRO:CNA]
|
Yes |
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organism-gene
|
|
PR:P27037 |
activin receptor type-2A (human)
|
hACVR2A
|
"An activin receptor type-2A that is encoded in the genome of human." [PRO:CNA, UniProtKB:P27037]
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organism-sequence
|
|
PR:P27037-1 |
activin receptor type-2A isoform 1 (human)
|
hACVR2A/iso:1
|
"An activin receptor type-2A isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P27037]
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organism-modification
|
|
PR:000036441 |
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (human)
|
hACVR2A/iso:1/GlycoPhos:1
|
"An activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 in human." [PMID:12665502, PMID:1314589, PMID:8622651, PRO:CNA]
|
Yes |
|
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| | |
organism-sequence
|
|
PR:P27037-2 |
activin receptor type-2A isoform h2 (human)
|
hACVR2A/iso:h2
|
"An activin receptor type-2A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27037-2." [PRO:DNx, UniProtKB:P27037]
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| | |
organism-modification
|
|
PR:000046258 |
activin receptor type-2A, signal peptide removed form (human)
|
hACVR2A/SigPep-
|
"An activin receptor type-2A (human) that has had the signal peptide removed. UniProtKB:P27037, 20-513." [PRO:DNx, Reactome:R-HSA-201659]
|
|
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organism-gene
|
|
PR:P27038 |
activin receptor type-2A (mouse)
|
mACVR2A
|
"An activin receptor type-2A that is encoded in the genome of mouse." [OMA:P27038, PRO:DNx]
|
|
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| | |
organism-sequence
|
|
PR:P27038-1 |
activin receptor type-2A isoform 1 (mouse)
|
mACVR2A/iso:1
|
"An activin receptor type-2A isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P27038]
|
Yes |
|
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|
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|
organism-modification
|
|
PR:000036440 |
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse)
|
mACVR2A/iso:1/GlycoPhos:1
|
"An activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 in mouse." [PMID:10452853, PMID:11459935, PMID:12414726, PMID:16991118, PMID:7885474, PMID:8395525, PMID:8612709, PRO:CNA]
|
Yes |
|
|
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|
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| | | | |
organism-gene
|
|
PR:P38444 |
activin receptor type-2A (rat)
|
rACVR2A
|
"An activin receptor type-2A that is encoded in the genome of rat." [OMA:P38444, PRO:DNx]
|
|
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organism-gene
|
|
PR:Q90669 |
activin receptor type-2A (chicken)
|
chick-ACVR2A
|
"An activin receptor type-2A that is encoded in the genome of chicken." [OMA:Q90669, PRO:DNx]
|
|
|
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|
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sequence
|
|
PR:000000208 |
activin receptor type-2A isoform 1
|
ACVR2A/iso:1
|
"An activin receptor type-2A that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27038-1 or a 1:1 ortholog thereof." [PMID:8395525, PRO:CNA, PRO:DAN]
|
|
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|
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| | |
organism-sequence
|
|
PR:P27037-1 |
activin receptor type-2A isoform 1 (human)
|
hACVR2A/iso:1
|
"An activin receptor type-2A isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P27037]
|
|
|
|
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|
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|
organism-modification
|
|
PR:000036441 |
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (human)
|
hACVR2A/iso:1/GlycoPhos:1
|
"An activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 in human." [PMID:12665502, PMID:1314589, PMID:8622651, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P27038-1 |
activin receptor type-2A isoform 1 (mouse)
|
mACVR2A/iso:1
|
"An activin receptor type-2A isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P27038]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036440 |
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse)
|
mACVR2A/iso:1/GlycoPhos:1
|
"An activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 in mouse." [PMID:10452853, PMID:11459935, PMID:12414726, PMID:16991118, PMID:7885474, PMID:8395525, PMID:8612709, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000414 |
activin receptor type-2A isoform 1 glycosylated and phosphorylated form
|
ACVR2A/iso:1/GlycoPhos+
|
"An activin receptor type-2A isoform 1 that includes at least one glycosylated residue and at least one phosphorylated residue." [PRO:CNA]
|
|
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|
|
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|
| | | | | | | | | | |
|
modification
|
|
PR:000000528 |
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1
|
ACVR2A/iso:1/GlycoPhos:1
|
"An activin receptor type-2A isoform 1 glycosylated and phosphorylated form in which the phosphorylation occurs at Ser/Thr residues. This constitutes the active receptor subunit." [PMID:8395525]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036440 |
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse)
|
mACVR2A/iso:1/GlycoPhos:1
|
"An activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 in mouse." [PMID:10452853, PMID:11459935, PMID:12414726, PMID:16991118, PMID:7885474, PMID:8395525, PMID:8612709, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036441 |
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (human)
|
hACVR2A/iso:1/GlycoPhos:1
|
"An activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 in human." [PMID:12665502, PMID:1314589, PMID:8622651, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | |
| | | | | | |
gene
|
|
PR:000000071 |
activin receptor type-2B
|
ACVR2B
|
"A TGF-beta superfamily receptor type-2 with activin receptor domain that is a translation product of the human ACVR2B gene or a 1:1 ortholog thereof." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:P27040 |
activin receptor type-2B (mouse)
|
mACVR2B
|
"An activin receptor type-2B that is encoded in the genome of mouse." [OMA:P27040, PRO:DNx]
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organism-sequence
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PR:P27040-1 |
activin receptor type-2B isoform ActR-IIB1 (mouse)
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mACVR2B/iso:ActR-IIB1
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"An activin receptor type-2B isoform ActR-IIB1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-sequence
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PR:P27040-2 |
activin receptor type-2B isoform ActR-IIB2 (mouse)
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mACVR2B/iso:ActR-IIB2
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"An activin receptor type-2B isoform ActR-IIB2 that is encoded in the genome of mouse." [PRO:CNA]
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organism-modification
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PR:000036442 |
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse)
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mACVR2B/iso:ActR-IIB2/NGlycoPhos:1
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"An activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 in mouse." [PMID:10452853, PMID:11459935, PMID:12414726, PMID:1326537, PMID:16991118, PMID:8721982, PRO:CNA]
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Yes |
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organism-sequence
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PR:P27040-3 |
activin receptor type-2B isoform ActR-IIB3 (mouse)
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mACVR2B/iso:ActR-IIB3
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"An activin receptor type-2B isoform ActR-IIB3 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-sequence
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PR:P27040-4 |
activin receptor type-2B isoform ActR-IIB4 (mouse)
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mACVR2B/iso:ActR-IIB4
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"An activin receptor type-2B isoform ActR-IIB4 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-gene
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PR:P38445 |
activin receptor type-2B (rat)
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rACVR2B
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"An activin receptor type-2B that is encoded in the genome of rat." [OMA:P38445, PRO:DNx]
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organism-gene
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PR:Q13705 |
activin receptor type-2B (human)
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hACVR2B
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"An activin receptor type-2B that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q13705]
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organism-sequence
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PR:000000214 |
activin receptor type-2B sequence variant R40H (human)
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hACVR2B/var:R40H
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"An activin receptor type-2B (human) that has a His residue at the position equivalent to Arg-40 of the amino acid sequence represented by UniProtKB:Q13705-1. This variation is within the extracellular domain. Example: UniProtKB:Q13705-1, Arg-40, CHEBI:29979." [PMID:9916847, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000215 |
activin receptor type-2B sequence variant V494I (human)
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hACVR2B/var:V494I
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"An activin receptor type-2B (human) that has an Ile residue at the position equivalent to Val-494 of the amino acid sequence represented by UniProtKB:Q13705-1. Example: UniProtKB:Q13705-1, Val-494, CHEBI:30009." [PMID:9916847, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:Q13705-1 |
activin receptor type-2B isoform ActR-IIB2 (human)
|
hACVR2B/iso:ActR-IIB2
|
"An activin receptor type-2B isoform ActR-IIB2 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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organism-modification
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PR:000036443 |
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (human)
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hACVR2B/iso:ActR-IIB2/NGlycoPhos:1
|
"An activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 in human." [PMID:11279102, PMID:24337809, PMID:8161782, PMID:8622651, PMID:9872992, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:Q13705-2 |
activin receptor type-2B isoform ActR-IIBtrunc (human)
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hACVR2B/iso:ActR-IIB1
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"An activin receptor type-2B isoform ActR-IIBtrunc that is encoded in the genome of human." [PMID:9916847, PRO:DNx, UniProtKB:Q13705]
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Yes |
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organism-modification
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PR:000046259 |
activin receptor type-2B, signal peptide removed form (human)
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hACVR2B/SigPep-
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"An activin receptor type-2B (human) that has had the signal peptide removed. UniProtKB:Q13705, 19-512." [PRO:DNx, Reactome:R-HSA-201656]
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organism-modification
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PR:000076998 |
activin receptor type-2B phosphorylated 1 (human)
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hACVR2B/Phos:1
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"An activin receptor type-2B (human) that has been phosphorylated on the residue at the position equivalent to Tyr-387 of the amino acid sequence represented by UniProtKB:Q13705-1. Example: UniProtKB:Q13705-1, Tyr-387, MOD:00048." [IEDB_epitope:2146498, PRO:DNx]
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organism-gene
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PR:Q90670 |
activin receptor type-2B (chicken)
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chick-ACVR2B
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"An activin receptor type-2B that is encoded in the genome of chicken." [OMA:Q90670, PRO:DNx]
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organism-sequence
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PR:Q90670-1 |
activin receptor type-2B isoform ActR-IIB2 (chicken)
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chick-ACVR2B/iso:ActR-IIB2
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"An activin receptor type-2B isoform ActR-IIB2 that is encoded in the genome of chicken." [PRO:CNA]
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sequence
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PR:000000209 |
activin receptor type-2B isoform ActR-IIB2
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ACVR2B/iso:ActR-IIB2
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"An activin receptor type-2B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27040-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:P27040-2 |
activin receptor type-2B isoform ActR-IIB2 (mouse)
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mACVR2B/iso:ActR-IIB2
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"An activin receptor type-2B isoform ActR-IIB2 that is encoded in the genome of mouse." [PRO:CNA]
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organism-modification
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PR:000036442 |
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse)
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mACVR2B/iso:ActR-IIB2/NGlycoPhos:1
|
"An activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 in mouse." [PMID:10452853, PMID:11459935, PMID:12414726, PMID:1326537, PMID:16991118, PMID:8721982, PRO:CNA]
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Yes |
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organism-sequence
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PR:Q13705-1 |
activin receptor type-2B isoform ActR-IIB2 (human)
|
hACVR2B/iso:ActR-IIB2
|
"An activin receptor type-2B isoform ActR-IIB2 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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organism-modification
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PR:000036443 |
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (human)
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hACVR2B/iso:ActR-IIB2/NGlycoPhos:1
|
"An activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 in human." [PMID:11279102, PMID:24337809, PMID:8161782, PMID:8622651, PMID:9872992, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:Q90670-1 |
activin receptor type-2B isoform ActR-IIB2 (chicken)
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chick-ACVR2B/iso:ActR-IIB2
|
"An activin receptor type-2B isoform ActR-IIB2 that is encoded in the genome of chicken." [PRO:CNA]
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modification
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PR:000000415 |
activin receptor type-2B isoform ActR-IIB2 glycosylated and phosphorylated form
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ACVR2B/iso:ActR-IIB2/GlycoPhos+
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"An activin receptor type-2B isoform ActR-IIB2 that includes at least one glycosylated residue and at least one phosphorylated residue." [PRO:CNA]
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modification
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PR:000000529 |
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1
|
ACVR2B/iso:ActR-IIB2/NGlycoPhos:1
|
"An activin receptor type-2B isoform ActR-IIB2 glycosylated and phosphorylated form in which the phosphorylation occurs at Ser/Thr residues within the GS-motif, and constitutes an active activin receptor subunit." [PRO:CNA]
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organism-modification
|
|
PR:000036442 |
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse)
|
mACVR2B/iso:ActR-IIB2/NGlycoPhos:1
|
"An activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 in mouse." [PMID:10452853, PMID:11459935, PMID:12414726, PMID:1326537, PMID:16991118, PMID:8721982, PRO:CNA]
|
Yes |
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organism-modification
|
|
PR:000036443 |
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (human)
|
hACVR2B/iso:ActR-IIB2/NGlycoPhos:1
|
"An activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 in human." [PMID:11279102, PMID:24337809, PMID:8161782, PMID:8622651, PMID:9872992, PRO:CNA, PRO:DAN]
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Yes |
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sequence
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PR:000000210 |
activin receptor type-2B isoform ActR-IIBtrunc
|
ACVR2B/iso:ActR-IIBtrunc
|
"An activin receptor type-2B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13705-2 or a 1:1 ortholog thereof." [PMID:9916847, PRO:CNA, PRO:DAN]
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organism-sequence
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PR:Q13705-2 |
activin receptor type-2B isoform ActR-IIBtrunc (human)
|
hACVR2B/iso:ActR-IIB1
|
"An activin receptor type-2B isoform ActR-IIBtrunc that is encoded in the genome of human." [PMID:9916847, PRO:DNx, UniProtKB:Q13705]
|
Yes |
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sequence
|
|
PR:000000211 |
activin receptor type-2B isoform ActR-IIB1
|
ACVR2B/iso:ActR-IIB1
|
"An activin receptor type-2B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27040-1 or a 1:1 ortholog thereof." [PMID:1310075, PRO:CNA, PRO:DAN]
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organism-sequence
|
|
PR:P27040-1 |
activin receptor type-2B isoform ActR-IIB1 (mouse)
|
mACVR2B/iso:ActR-IIB1
|
"An activin receptor type-2B isoform ActR-IIB1 that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
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sequence
|
|
PR:000000212 |
activin receptor type-2B isoform ActR-IIB3
|
ACVR2B/iso:ActR-IIB3
|
"An activin receptor type-2B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27040-3 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
|
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PR:P27040-3 |
activin receptor type-2B isoform ActR-IIB3 (mouse)
|
mACVR2B/iso:ActR-IIB3
|
"An activin receptor type-2B isoform ActR-IIB3 that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
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sequence
|
|
PR:000000213 |
activin receptor type-2B isoform ActR-IIB4
|
ACVR2B/iso:ActR-IIB4
|
"An activin receptor type-2B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27040-4 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
|
|
PR:P27040-4 |
activin receptor type-2B isoform ActR-IIB4 (mouse)
|
mACVR2B/iso:ActR-IIB4
|
"An activin receptor type-2B isoform ActR-IIB4 that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
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organism-gene
|
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PR:A0A0G2KN81 |
serine/threonine-protein kinase receptor (zebrafish)
|
z-ACVR2B
|
"A TGF-beta superfamily receptor type-2 with activin receptor domain that is a translation product of the acvr2b gene in zebrafish." [PRO:CNA, PRO:DAN]
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