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Protein Ontology report - TGF-beta receptor type-2

PR:000000005 - http://purl.obolibrary.org/obo/PR_000000005

Protein Forms

Complex

Annotations

Ontology Information

Show OBO stanza

PAF

PRO ID

PR:000000005

PRO name

TGF-beta receptor type-2

Synonyms

PRO-Short-label:	EXACT:	TGFBR2
Other:	EXACT:	TbetaR-II \| TGF-beta receptor type II \| TGF-beta type II receptor \| TGFR-2 \| transforming growth factor-beta receptor type II

Definition

"A protein that is a translation product of the human TGFBR2 gene or a 1:1 ortholog thereof." [PRO:CNA]

Comment

The core domain organization is composed of a signal peptide followed by a Transforming growth factor beta receptor 2 ectodomain (Pfam:PF08917), a transmembrane domain and a C-terminal Protein kinase domain (Pfam:PF00069).

PRO Category

gene

Parent

PR:000000001 protein

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Gene	1	Organism-Gene	4
Sequence	2	Organism-Sequence	21
Modification	7	Organism-Modification	9

Term Hierarchy
Visualization

DAG:

OLS:

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Related Cross References
Db identifiers	PIRSF:PIRSF037393;IUPHARobj:1795

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?

gene

PR:000000005 TGF-beta receptor type-2

TGFBR2

Yes

organism-gene

PR:P37173 TGF-beta receptor type-2 (human)

hTGFBR2

organism-sequence

PR:000000050 TGF-beta receptor type-2 sequence variant L308P (human)

hTGFBR2/var:L308P

Yes

organism-sequence

PR:000000051 TGF-beta receptor type-2 sequence variant R460H (human)

hTGFBR2/var:R460H

Yes

organism-sequence

PR:000000052 TGF-beta receptor type-2 sequence variant R460C (human)

hTGFBR2/var:R460C

Yes

organism-sequence

PR:000000053 TGF-beta receptor type-2 sequence variant E526Q (human)

hTGFBR2/var:E526Q

Yes

organism-sequence

PR:000000054 TGF-beta receptor type-2 sequence variant R528C (human)

hTGFBR2/var:R528C

Yes

organism-sequence

PR:000000055 TGF-beta receptor type-2 sequence variant R528H (human)

hTGFBR2/var:R528H

Yes

organism-sequence

PR:000000056 TGF-beta receptor type-2 sequence variant R537C (human)

hTGFBR2/var:R537C

Yes

organism-sequence

PR:000000057 TGF-beta receptor type-2 sequence variant G357W (human)

hTGFBR2/var:G357W

Yes

organism-sequence

PR:000000058 TGF-beta receptor type-2 sequence variant T315M (human)

hTGFBR2/var:T315M

Yes

organism-sequence

PR:000000059 TGF-beta receptor type-2 sequence variant Y336N (human)

hTGFBR2/var:Y336N

Yes

organism-sequence

PR:000000060 TGF-beta receptor type-2 sequence variant A355P (human)

hTGFBR2/var:A355P

Yes

organism-sequence

PR:000000061 TGF-beta receptor type-2 sequence variant V387M (human)

hTGFBR2/var:V387M

Yes

organism-sequence

PR:000000062 TGF-beta receptor type-2 sequence variant N435S (human)

hTGFBR2/var:N435S

Yes

organism-sequence

PR:000000063 TGF-beta receptor type-2 sequence variant V447A (human)

hTGFBR2/var:V447A

Yes

organism-sequence

PR:000000064 TGF-beta receptor type-2 sequence variant S449F (human)

hTGFBR2/var:S449F

Yes

organism-sequence

PR:000000065 TGF-beta receptor type-2 sequence variant L452M (human)

hTGFBR2/var:L452M

Yes

organism-sequence

PR:P37173-1 TGF-beta receptor type-2 isoform RII-1 (human)

hTGFBR2/iso:RII-1

organism-modification

PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human)

hTGFBR2/iso:RII-1/SigPep-

Yes

organism-modification

PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)

hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes

organism-sequence

PR:P37173-2 TGF-beta receptor type-2 isoform RII-2 (human)

hTGFBR2/iso:RII-2

Yes

organism-sequence

PR:P37173-3 TGF-beta receptor type-2 isoform h3 (human)

hTGFBR2/iso:h3

organism-modification

PR:000085798 TGF-beta receptor type-2, signal peptide removed form (human)

hTGFBR2/SigPep-

organism-modification

PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human)

hTGFBR2/iso:RII-1/SigPep-

Yes

organism-modification

PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)

hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes

organism-modification

PR:000049434 TGF-beta receptor type-2, signal peptide removed neddylated 1 (human)

hTGFBR2/SigPep-/Nedd:1

organism-modification

PR:000060724 TGF-beta receptor type-2 sequence variant Y470D, signal peptide removed form (human)

hTGFBR2/var:Y470D/SigPep-

organism-modification

PR:000062611 TGF-beta receptor type-2 sequence variant E526Q, signal peptide removed form (human)

hTGFBR2/var:E526Q/SigPep-

organism-modification

PR:000062709 TGF-beta receptor type-2 sequence variant R528C, signal peptide removed form (human)

hTGFBR2/var:R528C/SigPep-

organism-modification

PR:000062958 TGF-beta receptor type-2 sequence variant D522N, signal peptide removed form (human)

hTGFBR2/var:D522N/SigPep-

organism-modification

PR:000064130 TGF-beta receptor type-2 sequence variant R528H, signal peptide removed form (human)

hTGFBR2/var:R528H/SigPep-

organism-gene

PR:P38438 TGF-beta receptor type-2 (rat)

rTGFBR2

organism-gene

PR:Q62312 TGF-beta receptor type-2 (mouse)

mTGFBR2

organism-sequence

PR:Q62312-1 TGF-beta receptor type-2 isoform RII-2 (mouse)

mTGFBR2/iso:RII-2

Yes

organism-sequence

PR:Q62312-2 TGF-beta receptor type-2 isoform RII-1 (mouse)

mTGFBR2/iso:RII-1

Yes

organism-gene

PR:Q90999 TGF-beta receptor type-2 (chicken)

chick-TGFBR2

sequence

PR:000000048 TGF-beta receptor type-2 isoform RII-1

TGFBR2/iso:RII-1

organism-sequence

PR:P37173-1 TGF-beta receptor type-2 isoform RII-1 (human)

hTGFBR2/iso:RII-1

organism-modification

PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human)

hTGFBR2/iso:RII-1/SigPep-

Yes

organism-modification

PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)

hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes

organism-sequence

PR:Q62312-2 TGF-beta receptor type-2 isoform RII-1 (mouse)

mTGFBR2/iso:RII-1

Yes

modification

PR:000000198 TGF-beta receptor type-2 isoform RII-1 phosphorylated form

TGFBR2/iso:RII-1/PhosRes+

modification

PR:000000410 TGF-beta receptor type-2 isoform RII-1 phosphorylated 1

TGFBR2/iso:RII-1/Phos:1

modification

PR:000003175 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated form

TGFBR2/iso:RII-1/SigPep-/PhosRes+

modification

PR:000003176 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1

TGFBR2/iso:RII-1/SigPep-/Phos:1

Yes

organism-modification

PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)

hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes

modification

PR:000000409 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form

TGFBR2/iso:RII-1/SigPep-

modification

PR:000003175 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated form

TGFBR2/iso:RII-1/SigPep-/PhosRes+

modification

PR:000003176 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1

TGFBR2/iso:RII-1/SigPep-/Phos:1

Yes

organism-modification

PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)

hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes

organism-modification

PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human)

hTGFBR2/iso:RII-1/SigPep-

Yes

organism-modification

PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)

hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes

sequence

PR:000000049 TGF-beta receptor type-2 isoform RII-2

TGFBR2/iso:RII-2

organism-sequence

PR:P37173-2 TGF-beta receptor type-2 isoform RII-2 (human)

hTGFBR2/iso:RII-2

Yes

organism-sequence

PR:Q62312-1 TGF-beta receptor type-2 isoform RII-2 (mouse)

mTGFBR2/iso:RII-2

Yes

modification

PR:000018266 TGF-beta receptor type-2, signal peptide removed form

TGFBR2/SigPep-

modification

PR:000000409 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form

TGFBR2/iso:RII-1/SigPep-

modification

PR:000003175 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated form

TGFBR2/iso:RII-1/SigPep-/PhosRes+

modification

PR:000003176 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1

TGFBR2/iso:RII-1/SigPep-/Phos:1

Yes

organism-modification

PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)

hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes

organism-modification

PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human)

hTGFBR2/iso:RII-1/SigPep-

Yes

organism-modification

PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)

hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes

organism-modification

PR:000085798 TGF-beta receptor type-2, signal peptide removed form (human)

hTGFBR2/SigPep-

organism-modification

PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human)

hTGFBR2/iso:RII-1/SigPep-

Yes

organism-modification

PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human)

hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes

organism-modification

PR:000049434 TGF-beta receptor type-2, signal peptide removed neddylated 1 (human)

hTGFBR2/SigPep-/Nedd:1

organism-modification

PR:000060724 TGF-beta receptor type-2 sequence variant Y470D, signal peptide removed form (human)

hTGFBR2/var:Y470D/SigPep-

organism-modification

PR:000062611 TGF-beta receptor type-2 sequence variant E526Q, signal peptide removed form (human)

hTGFBR2/var:E526Q/SigPep-

organism-modification

PR:000062709 TGF-beta receptor type-2 sequence variant R528C, signal peptide removed form (human)

hTGFBR2/var:R528C/SigPep-

organism-modification

PR:000062958 TGF-beta receptor type-2 sequence variant D522N, signal peptide removed form (human)

hTGFBR2/var:D522N/SigPep-

organism-modification

PR:000064130 TGF-beta receptor type-2 sequence variant R528H, signal peptide removed form (human)

hTGFBR2/var:R528H/SigPep-

modification

PR:000025412 TGF-beta receptor type-2 proteolytic cleavage product

TGFBR2/ClvPrd

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TGFBR2 forms found in complexes

TGFBR2 Component	Complexes
PR:000003176 TGFBR2/iso:RII-1/SigPep-/Phos:1	PR:000025976 transforming growth factor beta type II receptor homodimeric complex phosphorylated form
PR:000025962 hTGFBR2/iso:RII-1/SigPep-/Phos:1	PR:000025963 transforming growth factor beta type II receptor homodimeric complex phosphorylated form (human)

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Functional Annotation (GO-centric view)

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Biological Process GO Term	Protein Forms & Complexes	Evidence
GO:0006468 protein phosphorylation	PR:000000005 TGFBR2	PIRSF:PIRSF037393
GO:0007179 transforming growth factor beta receptor signaling pathway	PR:000000005 TGFBR2	PIRSF:PIRSF037393
	PR:000000060 hTGFBR2/var:A355P	PMID:15731757
	PR:000000061 hTGFBR2/var:V387M	PMID:11212236
	PR:000000062 hTGFBR2/var:N435S	PMID:11212236
	PR:000000063 hTGFBR2/var:V447A	PMID:11212236
	PR:000000065 hTGFBR2/var:L452M	PMID:11212236
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:11483955
	PR:P37173-2 hTGFBR2/iso:RII-2	PMID:7959019; PMID:8635485
GO:0007181 transforming growth factor beta receptor complex assembly	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1310899; PMID:8774881
GO:0008284 positive regulation of cell population proliferation	PR:000000058 hTGFBR2/var:T315M	PMID:9590282
	PR:P37173-2 hTGFBR2/iso:RII-2	PMID:7959019
GO:0042127 regulation of cell population proliferation	PR:000000005 TGFBR2	PIRSF:PIRSF037393
Disease Associated GO Term	Protein Forms & Complexes	Evidence
DO:0050466 Loeys-Dietz syndrome	PR:000000050 hTGFBR2/var:L308P	PMID:15235604
	PR:000000051 hTGFBR2/var:R460H	PMID:15731757
	PR:000000052 hTGFBR2/var:R460C	PMID:15731757
	PR:000000054 hTGFBR2/var:R528C	PMID:15731757
	PR:000000055 hTGFBR2/var:R528H	PMID:15731757
	PR:000000056 hTGFBR2/var:R537C	PMID:15235604
	PR:000000057 hTGFBR2/var:G357W	PMID:15731757
	PR:000000059 hTGFBR2/var:Y336N	PMID:15731757
	PR:000000060 hTGFBR2/var:A355P	PMID:15731757
	PR:000000064 hTGFBR2/var:S449F	PMID:15235604
DO:3748 esophagus squamous cell carcinoma	PR:000000053 hTGFBR2/var:E526Q	PMID:10789724
DO:3883 Lynch syndrome	PR:000000058 hTGFBR2/var:T315M	PMID:9590282
Molecular Function GO Term	Protein Forms & Complexes	Evidence
GO:0004672 protein kinase activity	PR:000000005 TGFBR2	PIRSF:PIRSF037393
GO:0005026 transforming growth factor beta receptor activity, type II	PR:000000061 hTGFBR2/var:V387M	PMID:11212236
	PR:000000062 hTGFBR2/var:N435S	PMID:11212236
	PR:000000063 hTGFBR2/var:V447A	PMID:11212236
	PR:000000065 hTGFBR2/var:L452M	PMID:11212236
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:11483955
	PR:P37173-2 hTGFBR2/iso:RII-2	PMID:7959019; PMID:8635485
NOT GO:0005026 transforming growth factor beta receptor activity, type II	PR:000000050 hTGFBR2/var:L308P	PMID:15235604
	PR:000000053 hTGFBR2/var:E526Q	PMID:10789724
	PR:000000056 hTGFBR2/var:R537C	PMID:15235604
	PR:000000064 hTGFBR2/var:S449F	PMID:15235604
GO:0005515 protein binding	PR:000000005 TGFBR2	PIRSF:PIRSF037393
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1850637
GO:0050431 transforming growth factor beta binding	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:11850637; PMID:1310899
	PR:P37173-2 hTGFBR2/iso:RII-2	PMID:8635485
	PR:Q62312-1 mTGFBR2/iso:RII-2	PMID:7957954
Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0016020 membrane	PR:000000060 hTGFBR2/var:A355P	PMID:15731757
	PR:000000061 hTGFBR2/var:V387M	PMID:11212236
	PR:000000063 hTGFBR2/var:V447A	PMID:11212236
	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1310899
	PR:Q62312-1 mTGFBR2/iso:RII-2	PMID:7959019
	PR:Q62312-2 mTGFBR2/iso:RII-1	PMID:7957954