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Protein Ontology report - HLH DNA-binding protein inhibitor
PR:000000003 - http://purl.obolibrary.org/obo/PR_000000003
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000003   
  PRO nameHLH DNA-binding protein inhibitor 
  Synonyms
Other: EXACT:DNA-binding protein inhibitor ID
RELATED:ID protein
  Definition"A protein that belongs to the clade D of the bHLH proteins (see PMID:20219281) with a core domain composition consisting of a helix-loop-helix DNA-binding domain (Pfam:PF00010) (HLH), common to the basic HLH family of transcription factors, but lacking the DNA binding domain to the consensus E box response element (CANNTG). By binding to basic HLH transcription factors, proteins in this class regulate gene expression." [PMID:20219281, PRO:CNA] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene4                                                  Organism-Gene 12                                        
         Sequence5                                                  Organism-Sequence 12                                        
         Modification7                                                  Organism-Modification 15                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF005808
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000000003

HLH DNA-binding protein inhibitor

HLH DNA-binding protein inhibitor


"A protein that belongs to the clade D of the bHLH proteins (see PMID:20219281) with a core domain composition consisting of a helix-loop-helix DNA-binding domain (Pfam:PF00010) (HLH), common to the basic HLH family of transcription factors, but lacking the DNA binding domain to the consensus E box response element (CANNTG). By binding to basic HLH transcription factors, proteins in this class regulate gene expression." [PMID:20219281, PRO:CNA]

Yes

gene



PR:000000039

DNA-binding protein inhibitor ID-1

ID1


"An HLH DNA-binding protein inhibitor that is a translation product of the human ID1 gene or a 1:1 ortholog thereof. This gene has two conserved protein coding exons." [PRO:CNA]

Yes

organism-gene



PR:P20067

DNA-binding protein inhibitor ID-1 (mouse)

mID1


"A DNA-binding protein inhibitor ID-1 that is encoded in the genome of mouse." [OMA:P20067, PRO:DNx]

Yes

organism-sequence



PR:P20067-1

DNA-binding protein inhibitor ID-1 isoform Long (mouse)

mID1/iso:Long


"A DNA-binding protein inhibitor ID-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20067-1." [PRO:DNx, UniProtKB:P20067]


organism-sequence



PR:P20067-2

DNA-binding protein inhibitor ID-1 isoform Short (mouse)

mID1/iso:Short


"A DNA-binding protein inhibitor ID-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-gene



PR:P41134

DNA-binding protein inhibitor ID-1 (human)

hID1


"A DNA-binding protein inhibitor ID-1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P41134]

Yes

organism-sequence



PR:P41134-1

DNA-binding protein inhibitor ID-1 isoform ID-A (human)

hID1/iso:ID-A


"A DNA-binding protein inhibitor ID-1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-sequence



PR:P41134-2

DNA-binding protein inhibitor ID-1 isoform ID-B (human)

hID1/iso:ID-B


"A DNA-binding protein inhibitor ID-1 isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000071543

DNA-binding protein inhibitor ID-1 cysteinylated 1 (human)

hID1/Cyst:1


"A DNA-binding protein inhibitor ID-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-17 of the amino acid sequence represented by UniProtKB:P41134-1. Example: UniProtKB:P41134-1, Cys-17, MOD:00765." [IEDB_epitope:874821, PRO:DNx]


organism-gene



PR:P41135

DNA-binding protein inhibitor ID-1 (rat)

rID1


"A DNA-binding protein inhibitor ID-1 that is encoded in the genome of rat." [OMA:P41135, PRO:DNx]


organism-sequence



PR:P41135-1

DNA-binding protein inhibitor ID-1 isoform Long (rat)

rID1/iso:Long


"A DNA-binding protein inhibitor ID-1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41135-1." [PRO:DNx, UniProtKB:P41135]


organism-sequence



PR:P41135-2

DNA-binding protein inhibitor ID-1 isoform Short (rat)

rID1/iso:Short


"A DNA-binding protein inhibitor ID-1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41135-2." [PRO:DNx, UniProtKB:P41135]


sequence



PR:000000171

DNA-binding protein inhibitor ID-1 isoform 1

ID1/iso:1


"A DNA-binding protein inhibitor ID-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41134-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P20067-2

DNA-binding protein inhibitor ID-1 isoform Short (mouse)

mID1/iso:Short


"A DNA-binding protein inhibitor ID-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:P41134-1

DNA-binding protein inhibitor ID-1 isoform ID-A (human)

hID1/iso:ID-A


"A DNA-binding protein inhibitor ID-1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

sequence



PR:000000172

DNA-binding protein inhibitor ID-1 isoform 2

ID1/iso:2


"A DNA-binding protein inhibitor ID-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41134-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P41134-2

DNA-binding protein inhibitor ID-1 isoform ID-B (human)

hID1/iso:ID-B


"A DNA-binding protein inhibitor ID-1 isoform 2 that is encoded in the genome of human." [PRO:CNA]


gene



PR:000000040

DNA-binding protein inhibitor ID-2

ID2


"An HLH DNA-binding protein inhibitor that is a translation product of the human ID2 gene or a 1:1 ortholog thereof." [PRO:CNA]

Yes

organism-gene



PR:P41136

DNA-binding protein inhibitor ID-2 (mouse)

mID2


"A DNA-binding protein inhibitor ID-2 that is encoded in the genome of mouse." [OMA:P41136, PRO:DNx]


organism-sequence



PR:P41136-1

DNA-binding protein inhibitor ID-2 isoform 1 (mouse)

mID2/iso:1


"A DNA-binding protein inhibitor ID-2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000045376

DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 (mouse)

mID2/iso:1/UnPhos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 in mouse. UniProtKB:P41136-1, Ser-5, PR:000026291." [PRO:CNA]


organism-gene



PR:P41137

DNA-binding protein inhibitor ID-2 (rat)

rID2


"A DNA-binding protein inhibitor ID-2 that is encoded in the genome of rat." [OMA:P41137, PRO:DNx]


organism-modification



PR:000036428

DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 (rat)

rID2/iso:1/Phos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 in rat. UniProtKB:P41137-1, Ser-5, MOD:00046." [PMID:11706002, PRO:CNA]

Yes

organism-modification



PR:000045377

DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 (rat)

rID2/iso:1/UnPhos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 in rat. UniProtKB:P41137-1, Ser-5, PR:000026291." [PMID:11706002, PRO:CNA]

Yes

organism-gene



PR:Q02363

DNA-binding protein inhibitor ID-2 (human)

hID2


"A DNA-binding protein inhibitor ID-2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q02363]


organism-sequence



PR:Q02363-1

DNA-binding protein inhibitor ID-2 isoform 1 (human)

hID2/iso:1


"A DNA-binding protein inhibitor ID-2 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036427

DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 (human)

hID2/iso:1/Phos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 in human. UniProtKB:Q02363-1, Ser-5, MOD:00046." [PMID:9029153, PRO:CNA]

Yes

organism-modification



PR:000045368

DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 (human)

hID2/iso:1/UnPhos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 in human. UniProtKB:Q02363-1, Ser-5, PR:000026291." [PMID:9029153, PRO:CNA]

Yes

organism-modification



PR:000069807

DNA-binding protein inhibitor ID-2 sulfated 1 (human)

hID2/Sulf:1


"A DNA-binding protein inhibitor ID-2 (human) that has been sulfated on the residue at the position equivalent to Ser-5 of the amino acid sequence represented by UniProtKB:Q02363. UniProtKB:Q02363, Ser-5, MOD:00366." [IEDB_epitope:1392990, PRO:DNx]


organism-modification



PR:000079087

DNA-binding protein inhibitor ID-2 phosphorylated 1 (human)

hID2/Phos:1


"A DNA-binding protein inhibitor ID-2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-5 of the amino acid sequence represented by UniProtKB:Q02363. UniProtKB:Q02363, Ser-5, MOD:00046." [IEDB_epitope:845632, PRO:DNx]


sequence



PR:000000173

DNA-binding protein inhibitor ID-2 isoform 1

ID2/iso:1


"A DNA-binding protein inhibitor ID-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02363-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P41136-1

DNA-binding protein inhibitor ID-2 isoform 1 (mouse)

mID2/iso:1


"A DNA-binding protein inhibitor ID-2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000045376

DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 (mouse)

mID2/iso:1/UnPhos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 in mouse. UniProtKB:P41136-1, Ser-5, PR:000026291." [PRO:CNA]


organism-sequence



PR:Q02363-1

DNA-binding protein inhibitor ID-2 isoform 1 (human)

hID2/iso:1


"A DNA-binding protein inhibitor ID-2 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036427

DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 (human)

hID2/iso:1/Phos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 in human. UniProtKB:Q02363-1, Ser-5, MOD:00046." [PMID:9029153, PRO:CNA]

Yes

organism-modification



PR:000045368

DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 (human)

hID2/iso:1/UnPhos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 in human. UniProtKB:Q02363-1, Ser-5, PR:000026291." [PMID:9029153, PRO:CNA]

Yes

modification



PR:000000392

DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated form

ID2/iso:1/PhosRes+


"A DNA-binding protein inhibitor ID-2 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000000507

DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1

ID2/iso:1/Phos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated form in which the phosphorylation occurs at the Ser residue in the N-terminal SPVR motif. Example: UniProtKB:Q02363-1, Ser-5, MOD:00046." [PMID:9029153]


organism-modification



PR:000036427

DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 (human)

hID2/iso:1/Phos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 in human. UniProtKB:Q02363-1, Ser-5, MOD:00046." [PMID:9029153, PRO:CNA]

Yes

organism-modification



PR:000036428

DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 (rat)

rID2/iso:1/Phos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 in rat. UniProtKB:P41137-1, Ser-5, MOD:00046." [PMID:11706002, PRO:CNA]

Yes

modification



PR:000045375

DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1

ID2/iso:1/PhosRes-


"A DNA-binding protein inhibitor ID-2 isoform 1 that lacks phosphorylation on the N-terminal SPVR motif. Example: UniProtKB:Q02363-1, Ser-5, PR:000026291." [PMID:11706002, PMID:9029153, PRO:CNA]


organism-modification



PR:000045368

DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 (human)

hID2/iso:1/UnPhos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 in human. UniProtKB:Q02363-1, Ser-5, PR:000026291." [PMID:9029153, PRO:CNA]

Yes

organism-modification



PR:000045376

DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 (mouse)

mID2/iso:1/UnPhos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 in mouse. UniProtKB:P41136-1, Ser-5, PR:000026291." [PRO:CNA]


organism-modification



PR:000045377

DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 (rat)

rID2/iso:1/UnPhos:1


"A DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 in rat. UniProtKB:P41137-1, Ser-5, PR:000026291." [PMID:11706002, PRO:CNA]

Yes

gene



PR:000000041

DNA-binding protein inhibitor ID-3

ID3


"An HLH DNA-binding protein inhibitor that is a translation product of the human ID3 gene or a 1:1 ortholog thereof." [PRO:CNA]

Yes

organism-gene



PR:P41133

DNA-binding protein inhibitor ID-3 (mouse)

mID3


"A DNA-binding protein inhibitor ID-3 that is encoded in the genome of mouse." [OMA:P41133, PRO:DNx]


organism-sequence



PR:P41133-1

DNA-binding protein inhibitor ID-3 isoform 1 (mouse)

mID3/iso:1


"A DNA-binding protein inhibitor ID-3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000036430

DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated 1 (mouse)

mID3/iso:1/Ubiq:1


"A DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated 1 in mouse." [PMID:15451666, PRO:CNA]

Yes

organism-gene



PR:P41138

DNA-binding protein inhibitor ID-3 (rat)

rID3


"A DNA-binding protein inhibitor ID-3 that is encoded in the genome of rat." [OMA:P41138, PRO:DNx]


organism-gene



PR:Q02535

DNA-binding protein inhibitor ID-3 (human)

hID3


"A DNA-binding protein inhibitor ID-3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q02535]

Yes

organism-sequence



PR:Q02535-1

DNA-binding protein inhibitor ID-3 isoform 1 (human)

hID3/iso:1


"A DNA-binding protein inhibitor ID-3 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036429

DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated 1 (human)

hID3/iso:1/Phos:1


"A DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated 1 in human. UniProtKB:Q02535-1, Ser-5, MOD:00046." [PMID:9372912, PRO:CNA]

Yes

organism-modification



PR:000064894

DNA-binding protein inhibitor ID-3 methylated 1 (human)

hID3/Me:1


"A DNA-binding protein inhibitor ID-3 (human) that has been methylated on the residue at the position equivalent to Cys-47 of the amino acid sequence represented by UniProtKB:Q02535. UniProtKB:Q02535, Cys-47, MOD:00660." [IEDB_epitope:1005759, IEDB_epitope:1017395, PRO:DNx]


organism-modification



PR:000068204

DNA-binding protein inhibitor ID-3 cysteinylated 1 (human)

hID3/Cyst:1


"A DNA-binding protein inhibitor ID-3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-47 of the amino acid sequence represented by UniProtKB:Q02535. UniProtKB:Q02535, Cys-47, MOD:00765." [IEDB_epitope:1587286, IEDB_epitope:880823, IEDB_epitope:926470, PRO:DNx]


organism-modification



PR:000073735

DNA-binding protein inhibitor ID-3 methylated 2 (human)

hID3/Me:2


"A DNA-binding protein inhibitor ID-3 (human) that has been methylated on the residue at the position equivalent to Cys-10 of the amino acid sequence represented by UniProtKB:Q02535. UniProtKB:Q02535, Cys-10, MOD:00660." [IEDB_epitope:1000695, IEDB_epitope:1050989, PRO:DNx]


organism-modification



PR:000081463

DNA-binding protein inhibitor ID-3 cysteinylated 2 (human)

hID3/Cyst:2


"A DNA-binding protein inhibitor ID-3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-10 of the amino acid sequence represented by UniProtKB:Q02535. UniProtKB:Q02535, Cys-10, MOD:00765." [IEDB_epitope:1000694, PRO:DNx]


organism-modification



PR:000082453

DNA-binding protein inhibitor ID-3 phosphorylated 1 (human)

hID3/Phos:1


"A DNA-binding protein inhibitor ID-3 (human) that has been phosphorylated on the residue at the position equivalent to Ser-5 of the amino acid sequence represented by UniProtKB:Q02535. UniProtKB:Q02535, Ser-5, MOD:00046." [IEDB_epitope:1626412, PRO:DNx]


sequence



PR:000000174

DNA-binding protein inhibitor ID-3 isoform 1

ID3/iso:1


"A DNA-binding protein inhibitor ID-3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02535-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:P41133-1

DNA-binding protein inhibitor ID-3 isoform 1 (mouse)

mID3/iso:1


"A DNA-binding protein inhibitor ID-3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000036430

DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated 1 (mouse)

mID3/iso:1/Ubiq:1


"A DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated 1 in mouse." [PMID:15451666, PRO:CNA]

Yes

organism-sequence



PR:Q02535-1

DNA-binding protein inhibitor ID-3 isoform 1 (human)

hID3/iso:1


"A DNA-binding protein inhibitor ID-3 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036429

DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated 1 (human)

hID3/iso:1/Phos:1


"A DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated 1 in human. UniProtKB:Q02535-1, Ser-5, MOD:00046." [PMID:9372912, PRO:CNA]

Yes

modification



PR:000000393

DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated form

ID3/iso:1/PhosRes+


"A DNA-binding protein inhibitor ID-3 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000000508

DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated 1

ID3/iso:1/Phos:1


"A DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated form in which the phosphorylation occurs at the Ser residue in the N-terminal SPVR motif. Example: UniProtKB:Q02535-1, Ser-5, MOD:00046." [PRO:CNA, PRO:DAN]


organism-modification



PR:000036429

DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated 1 (human)

hID3/iso:1/Phos:1


"A DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated 1 in human. UniProtKB:Q02535-1, Ser-5, MOD:00046." [PMID:9372912, PRO:CNA]

Yes

modification



PR:000000394

DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated form

ID3/iso:1/UbiqLys+


"A DNA-binding protein inhibitor ID-3 isoform 1 that includes at least one ubiquitinated lysine." [PRO:CNA]


modification



PR:000000509

DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated 1

ID3/iso:1/Ubiq:1


"A DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated form that has been ubiquitinated by COP9 signalosome complex for degradation." [PMID:15451666, PRO:CNA]


organism-modification



PR:000036430

DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated 1 (mouse)

mID3/iso:1/Ubiq:1


"A DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated 1 in mouse." [PMID:15451666, PRO:CNA]

Yes

gene



PR:000000042

DNA-binding protein inhibitor ID-4

ID4


"An HLH DNA-binding protein inhibitor that is a translation product of the human ID4 gene or a 1:1 ortholog thereof." [PRO:CNA]

Yes

organism-gene



PR:P41139

DNA-binding protein inhibitor ID-4 (mouse)

mID4


"A DNA-binding protein inhibitor ID-4 that is encoded in the genome of mouse." [OMA:P41139, PRO:DNx]


organism-sequence



PR:P41139-1

DNA-binding protein inhibitor ID-4 isoform 1 (mouse)

mID4/iso:1


"A DNA-binding protein inhibitor ID-4 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-gene



PR:P47928

DNA-binding protein inhibitor ID-4 (human)

hID4


"A DNA-binding protein inhibitor ID-4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P47928]


organism-sequence



PR:P47928-1

DNA-binding protein inhibitor ID-4 isoform 1 (human)

hID4/iso:1


"A DNA-binding protein inhibitor ID-4 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-gene



PR:Q90X12

helix-loop-helix protein (chicken)

chick-ID4


"A DNA-binding protein inhibitor ID-4 that is encoded in the genome of chicken." [PANTHER:PTHR11723:SF6, PRO:DNx]


sequence



PR:000000175

DNA-binding protein inhibitor ID-4 isoform 1

ID4/iso:1


"A DNA-binding protein inhibitor ID-4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47928-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:P41139-1

DNA-binding protein inhibitor ID-4 isoform 1 (mouse)

mID4/iso:1


"A DNA-binding protein inhibitor ID-4 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:P47928-1

DNA-binding protein inhibitor ID-4 isoform 1 (human)

hID4/iso:1


"A DNA-binding protein inhibitor ID-4 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000003 HLH DNA-binding protein inhibitor
By binding to basic HLH transcription factors, proteins in this class regulate gene expression
acts_upstream_of_or_withinGO:0006355 regulation of DNA-templated transcription PIRSF:PIRSF005808
enablesGO:0003700 DNA-binding transcription factor activity PIRSF:PIRSF005808
PR:000000039 ID1
This gene has two conserved protein coding exons
enablesGO:0046983 protein dimerization activity PANTHER:PTHR11723; PIRSF:PIRSF500477
PR:000000040 ID2 acts_upstream_of_or_withinGO:0045892 negative regulation of DNA-templated transcription PIRSF:PIRSF500478
PR:000000041 ID3 acts_upstream_of_or_withinGO:0045892 negative regulation of DNA-templated transcription PIRSF:PIRSF500479
PR:000000042 ID4 acts_upstream_of_or_withinGO:0045892 negative regulation of DNA-templated transcription PIRSF:PIRSF500478
PR:000036427 hID2/iso:1/Phos:1
UniProtKB:Q02363-1, Ser-5, MOD:00046
acts_upstream_of_or_withinGO:0051726 regulation of cell cycle PMID:9029153
PR:000036428 rID2/iso:1/Phos:1
UniProtKB:P41137-1, Ser-5, MOD:00046
located_inGO:0005634 nucleus PMID:11706002
PR:000036429 hID3/iso:1/Phos:1
UniProtKB:Q02535-1, Ser-5, MOD:00046
acts_upstream_of_or_withinGO:0051726 regulation of cell cycle PMID:9372912
PR:000036430 mID3/iso:1/Ubiq:1 located_inGO:0005737 cytoplasm PMID:15451666
PR:000045368 hID2/iso:1/UnPhos:1
UniProtKB:Q02363-1, Ser-5, PR:000026291
acts_upstream_of_or_withinGO:0045892 negative regulation of DNA-templated transcription PMID:14627819; PMID:9029153
PR:000045377 rID2/iso:1/UnPhos:1
UniProtKB:P41137-1, Ser-5, PR:000026291
located_inGO:0005737 cytoplasm PMID:11706002
PR:P20067 mID1 acts_upstream_of_or_withinGO:0000122 negative regulation of transcription by RNA polymerase II PMID:12498716
GO:0030509 BMP signaling pathway PMID:15820682
PR:P41133-1 mID3/iso:1 acts_upstream_of_or_withinGO:0000122 negative regulation of transcription by RNA polymerase II PMID:2000388
located_inGO:0005634 nucleus PMID:15451666
PR:P41134 hID1 acts_upstream_of_or_withinGO:0045892 negative regulation of DNA-templated transcription PMID:15138269
located_inGO:0005634 nucleus PMID:15138269
PR:P41134-1 hID1/iso:ID-A acts_upstream_of_or_withinGO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction PMID:17855368
enablesGO:0005515 protein binding with PR:Q03135 CAV PMID:17855368
located_inGO:0005737 cytoplasm PMID:17855368
PR:P41136-1 mID2/iso:1 enablesGO:0046983 protein dimerization activity PMID:10891368
located_inGO:0005634 nucleus PMID:12878164
GO:0005737 cytoplasm PMID:12878164; PMID:15563451
PR:P41139-1 mID4/iso:1 acts_upstream_of_or_withinGO:0008284 positive regulation of cell population proliferation PMID:15882580
GO:0030509 BMP signaling pathway PMID:15280210
GO:0045665 negative regulation of neuron differentiation PMID:15882580
GO:0045892 negative regulation of DNA-templated transcription PMID:8139914
enablesGO:0005515 protein binding with PR:Q03135 CAV PMID:15280210
GO:0005515 protein binding with PR:Q9JKN5 mOLIG1 PMID:15280210
located_inGO:0005737 cytoplasm PMID:15280210
PR:P47928-1 hID4/iso:1 acts_upstream_of_or_withinGO:0045892 negative regulation of DNA-templated transcription PMID:11136250
PR:Q02535 hID3 acts_upstream_of_or_withinGO:0045892 negative regulation of DNA-templated transcription PMID:14627819
PR:Q02535-1 hID3/iso:1 acts_upstream_of_or_withinGO:0007275 multicellular organism development PMID:1628620
GO:0045892 negative regulation of DNA-templated transcription PMID:8437843
enablesGO:0003714 transcription corepressor activity PMID:8437843